Inhibition of IRGM establishes a robust antiviral immune state to restrict pathogenic viruses
Report
[키워드] Antigen presentation
Antiviral
Cell
cells
Chikungunya
CHIKV
conditions
Coronaviridae
Defense
expression
FIVE
Herpesviridae
highlight
Host
human IRGM
IFITMs
IFN
IFN response
immune
immunology
Infection
inhibition
IRGM
IRGM1
knockout mice
Microbiology, Virology & Host Pathogen Interaction
PAMP
pathogenic virus
promote
regulate
regulated
remained
restrict
restriction factor
Rhabdoviridae
robust
SAMHD1
SARS‐CoV‐2
SARS‑CoV2
SARS‐CoV‐2
Seven
Signal transduction
Signaling
Stress
therapeutic target
Togaviridae
Trigger
type I interferon
viral infection
virus
viruses
Zika virus
ZIKV
[DOI] 10.15252/embr.202152948 PMC 바로가기 [Article Type] Report
[DOI] 10.15252/embr.202152948 PMC 바로가기 [Article Type] Report