Overcoming Challenges for CD3-Bispecific Antibody Therapy in Solid TumorsReview Published on 2021-01-142023-08-30 Journal: Cancers [Category] E형 간염, [키워드] Antibody therapy CD3-bispecific antibody Immuno-oncology on-target off-tumor toxicity solid tumors T-cell co-stimulation T-cell engager tumor-associated antigens [DOI] 10.3390/cancers13020287 PMC 바로가기 [Article Type] Review
The effect of anticancer treatment on cancer patients with COVID‐19: A systematic review and meta‐analysisReview Published on 2020-12-312022-10-31 Journal: Cancer Medicine [Category] COVID-19, MERS, SARS, [키워드] addition adopted Analysis analyzed anticancer Anticancer therapy Cancer cancer patient Characteristics Chemotherapy CNKI Cochrane Library conducted COVID‐19 COVID‐19 Effect Egger forest plot had no Hematological malignancies Hematological malignancy Hypothesis ICU admission inclusion criteria Mortality negative influence no significant difference NOS outcome pandemic Patient Patients with cancer Prospective Study receiving reported Respiratory Support Result significant difference solid tumor solid tumors Support systematic review the patient Treatment VIP were assessed [DOI] 10.1002/cam4.3692 PMC 바로가기 [Article Type] Review
Clinical characteristics, outcomes, and risk factors for mortality in hospitalized patients with COVID-19 and cancer history: a propensity score-matched studyResearch Article Published on 2020-12-172022-10-30 Journal: Infectious Agents and Cancer [Category] COVID-19, [키워드] 95% confidence interval age Analysis Cancer case control study case-control study caused Characteristics Chest computed tomography chest CT scan clinical Clinical data Comorbidities conducted confounders consequence controls COVID-19 COVID-19 adult patient COVID-19 patient death demographic determine Diabetes Mellitus Diagnosis Dyspnea Features female Fever Gender hematologic Hematologic malignancy hospital Hospital stay hospitalized patient hypertension IHD increased risk Infection ischemic heart disease Laboratory Leukocytosis Logistic regression Medical conditions Mortality mortality rate non-cancerous Older outcomes Patient patients patients’ medical records PCR-confirmed COVID-19 Poisson regression predict presenting symptom prognosis of patient propensity score matching recruited Result risk factor severe clinical events significantly solid tumor solid tumors survival survived Symptoms Tachycardia tachypnea underlying disease vital signs was used with COVID-19 [DOI] 10.1186/s13027-020-00339-y PMC 바로가기 [Article Type] Research Article
Older cancer patients and COVID‐19 outbreak: Practical considerations and recommendationsReview Published on 2020-11-212022-10-31 Journal: Cancer Medicine [Category] COVID-19, MERS, SARS, [키워드] addressed affecting Cancer cancer patient Care Chemotherapy consensus paper COVID‐19 COVID‐19 death disease elderly Evidence greater guidelines Hematological malignancies individual individuals lack maintain management manuscript Older older patient outbreak Palliative care promote provide recommendation resource risk seasonal flu solid tumors specific disease treated Treatment vaccination [DOI] 10.1002/cam4.3517 PMC 바로가기 [Article Type] Review
COVID-19 in cancer patients: clinical characteristics and outcome—an analysis of the LEOSS registry암 환자의 COVID-19: 임상 특성 및 결과 - LEOSS 레지스트리 분석Multicenter Study Published on 2020-11-072022-09-10 Journal: Annals of Hematology [Category] MERS, SARS, 치료기술, [키워드] active malignancy Adjusted analysis advanced age age age distribution Analysis analyzed anti-cancer treatments assumed Cancer cancer patient Cancer patients Clinical characteristics Cohort cohort study collected Comorbidities Comorbidity comparable conditions Course COVID-19 death rates determine distribution Endpoint enrolled European feature female higher risk ICU admission Infection LEOSS leukemia lymphoma majority Male sex malignancy mild symptoms Mortality mortality rate open outcome p value pandemic Patient patients primary endpoint Result Risk factors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic severe COVID-19 Sex significantly Solid solid tumors supplementary material survey the early SARS-CoV-2 Tumor tumors was performed [DOI] 10.1007/s00277-020-04328-4 PMC 바로가기 [Article Type] Multicenter Study
Comparative analysis of SARS-CoV-2 receptor ACE2 expression in multiple solid tumors and matched non-diseased tissues다발성 고형종양 및 비병적 조직에서 SARS-CoV-2 수용체 ACE2 발현 비교 분석Comparative Study Published on 2020-11-012022-09-12 Journal: Infection, genetics and evolution : journal of mol [Category] 진단, [키워드] ACE2 ACE2 expression ACE2 mRNA acute respiratory syndrome Cancer cellular entry characterized Comparative analysis coronavirus eight expression global public health high risk host cell receptor lung Non-diseased tissues Patient SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 receptor severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Solid solid tumor solid tumors tissue tissue sample tissues Treatment tumors [DOI] 10.1016/j.meegid.2020.104428 PMC 바로가기 [Article Type] Comparative Study
Cancer inpatients with COVID-19: A report from the Brazilian National Cancer InstituteResearch Article Published on 2020-10-262022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] accounted Acute kidney injury Admission age Analysis Antibiotics C-reactive protein Cancer cancer patient Chemotherapy Clinical characteristics clinical outcomes Cohort Complication COVID-19 COVID-19 complications death disease electronic medical record Hematological malignancies higher risk Inpatient leukemia lung lymphoma metastatic Mortality mortality rate National Cancer Institute objective patients patients died patients with COVID-19 prevalent Respiratory failure Result retrospective RT-PCR Septic shock significantly solid tumor solid tumors supportive care symptoms of COVID-19 Treatment Univariate analysis with COVID-19 [DOI] 10.1371/journal.pone.0241261 PMC 바로가기 [Article Type] Research Article
Impact of hematologic malignancy and type of cancer therapy on COVID-19 severity and mortality: lessons from a large population-based registry studyResearch Published on 2020-10-082022-10-29 Journal: Journal of Hematology & Oncology [Category] COVID-19, MERS, SARS, [키워드] active cancer acute respiratory syndrome adjusted age all-cause mortality analyses Analysis Antiviral antiviral therapy association Cancer Cancer therapy case sery Chemotherapy clinical Clinical characteristics Clinical severity collected combination therapy Comorbidities Comorbidity Coronavirus-2 COVID-19 COVID-19 in patient COVID-19 severity Cox regression criteria Cutoff develop died disease severity evaluate Health Service healthcare Hematologic malignancy hematologic neoplasms Hematological malignancy higher risk hospital Immunosuppression Impact Infection IQR leukemia Long-term follow-up lower mortality lymphoid male monoclonal antibody Mortality myeloid malignancies myeloproliferative neoplasm Non-Hodgkin Lymphoma outcome Patient patients patients with COVID-19 Prognostic factor reported required respiratory viral infection Result risk stratification SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) severity of COVID-19 Sex shown solid tumors Spain therapy Treatment [DOI] 10.1186/s13045-020-00970-7 PMC 바로가기 [Article Type] Research
Screening and Prophylaxis to Prevent Hepatitis B Reactivation: Patients with Hematological and Solid Tumor MalignanciesReview Published on 2019-08-012023-06-18 Journal: Clinics in Liver Disease [Category] B형 간염, [키워드] Cancer Hematological malignancy hepatitis B Prophylaxis Reactivation rituximab solid tumors [DOI] 10.1016/j.cld.2019.04.011 [Article Type] Review
CAR T Cells for Solid Tumors: New Strategies for Finding, Infiltrating, and Surviving in the Tumor MicroenvironmentReview Published on 2019-02-052023-08-30 Journal: Frontiers in Immunology [Category] E형 간염, [키워드] adoptive T cell immunotherapy chimeric antigen receptor engineered T cells solid tumors T cell [DOI] 10.3389/fimmu.2019.00128 PMC 바로가기 [Article Type] Review