stem cell – Page 5 – Communicable Diseases Research

Stem cell therapy for COVID-19 pneumonia

Review

Published on 2022-02-172022-10-30
Journal: Molecular Biomedicine [Category] COVID-19,

Neurogenesis and Viral Infection

Immunology

Published on 2022-02-172022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, MERS,

Application of Wharton jelly-derived mesenchymal stem cells in patients with pulmonary fibrosis

Review

Published on 2022-02-152023-06-12
Journal: Stem Cell Research & Therapy [Category] MERS,

[키워드] Cell-based therapy pulmonary fibrosis stem cell WJ-MSC
[DOI] 10.1186/s13287-022-02746-x PMC 바로가기 [Article Type] Review

E-series resolvin metabolome, biosynthesis and critical role of stereochemistry of specialized pro-resolving mediators (SPMs) in inflammation-resolution: Preparing SPMs for long COVID-19, human clinical trials, and targeted precision nutrition

Review article

Published on 2022-02-012022-10-05
Journal: Seminars in Immunology [Category] 임상,

[키워드] absorbance activate activating Acute inflammation acute inflammatory response adaptive apoptotic cells approach B-cells biosynthesized blood clot caused cellular response clinical study clinical trials Complete COVID-19 COVID-19 infection COVID-19 pandemic Critical defined disease Disease model docosahexaenoic acid (DHA) Eicosapentaenoic acid (EPA) EPA essential fatty acid Evidence excessive inflammation Fatty acid function functional Health homeostasis human clinical trials Human phagocytes human tissue Immune cell Inflammation Inflammatory innate immune cell Interaction International Ligand local inflammation loci lymphocyte M2 macrophages Macrophage Maresin mechanism mechanisms metabolome MS2 Neutrophils omega-3 Omega-3 polyunsaturated fatty acids organ Pathogens phagocyte physical Precision precursor Preparing Protective raised required Resolvin Specific stem cell stimulate Structure structures subset surface receptor T-cell Tandem mass spectrometry tissue regeneration unique
[DOI] 10.1016/j.smim.2022.101597 [Article Type] Review article

Cardiovascular events and safety outcomes associated with remdesivir using a World Health Organization international pharmacovigilance database

세계보건기구(WHO) 국제 약물감시 데이터베이스를 사용한 렘데시비르와 관련된 심혈관 사건 및 안전성 결과

Article

Published on 2022-02-012022-09-11
Journal: Clinical and translational science [Category] COVID19(2023년), SARS, 치료제,

[키워드] 95% CI 95% confidence interval adjusted odds ratio ADRS Adverse drug reaction Adverse drug reactions Analysis approved bradycardia Cardiac arrest Cardiotoxicity cardiovascular Cell cell viability components conducted confounders consequence coronavirus disease Coronavirus disease 2019 COVID-19 database demonstrated dose-dependent drug Effects event FDA food Health Organization Hypotension in vitro experiment information International maintain Odds ratio outcome patients with COVID-19 performed physician reduced Remdesivir reported safety margin stem cell tolerable toxicities Toxicity Treatment US Food and Drug Administration viability WHO World Health Organization
[DOI] 10.1111/cts.13168 PMC 바로가기 [Article Type] Article

Cytokine Storm in COVID-19: Immunopathogenesis and Therapy

COVID-19의 사이토카인 폭풍: 면역 병인 및 치료

Review

Published on 2022-01-182022-09-12
Journal: Medicina [Category] SARS, 진단,

[키워드] administration affected Allogeneic allogeneic hematopoietic stem cell transplantation Anakinra antibody autoinflammatory disease CAR Care clinically Coagulopathy conditions coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients Critically ill critically ill patients cytokine cytokine inhibitors Cytokine storm Cytokines death deregulated disease disease severity effective effort excessive production of cytokines glucocorticoid Glucocorticoids GM-CSF Graft Graft-versus-host disease Hematopoietic stem cell hemophagocytic lymphohistiocytosis Hope hyperinflammatory state IFN-γ IL-1 IL-10 IL-2 IL-6 immune cells immune system IP-10 jak inhibitors leading MCP-1 Methylene blue mitigate multi-organ failure Novel coronavirus novel coronavirus disease overcome pandemic Pathogenesis Patient Plasmapheresis pro-inflammatory cytokines reducing mortality secondary hemophagocytic lymphohistiocytosis secondary to Sepsis severe cases stem cell Stem cell transplantation storm syndrome T-cell tested the cytokine storm the disease therapeutic strategy therapy TNF-α to define Tocilizumab
[DOI] 10.3390/medicina58020144 PMC 바로가기 [Article Type] Review

Direct comparison of different therapeutic cell types susceptibility to inflammatory cytokines associated with COVID-19 acute lung injury

COVID-19 급성 폐 손상과 관련된 염증성 사이토카인에 대한 다양한 치료 세포 유형 감수성의 직접 비교

Research

Published on 2022-01-152022-09-10
Journal: Stem Cell Research & Therapy [Category] SARS, 유전자 메커니즘, 진단,

[키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome Alter Analysis ARDS ARDS patients Bone marrow Cell Cell therapy cell type cell viability cells characterized clinical evaluation clinical trial clinically Combination conditioned media COVID-19 COVID-19 ARDS patient cytokine Cytokine storm Cytokines Cytometry deleterious effect determine Direct Disease progression dose doses dysregulated immune response evaluate the effect excluded expression Extracellular Extracellular vesicles Flow flow cytometry greater high risk IL-6 immunomodulatory implicated Infection Inflammatory cytokine Inflammatory cytokines inflammatory mediator Inflammatory mediators mediators Mesenchymal stromal cells Mild Mortality not altered Novel coronavirus paracrine pathology Patient pro-inflammatory mediator pro-inflammatory mediators progression proteomic receptor receptors respiratory distress Respiratory distress syndrome Result severe ARDS severe COVID-19 stem cell stem cells stromal cells supplementary material survival susceptibility syndrome the cell therapeutic therapeutic efficacy therapy Treatment umbilical Vesicle viability were assessed widespread with COVID-19
[DOI] 10.1186/s13287-021-02699-7 PMC 바로가기 [Article Type] Research

Pulmonary Mesenchymal Stem Cells in Mild Cases of COVID-19 Are Dedicated to Proliferation; In Severe Cases, They Control Inflammation, Make Cell Dispersion, and Tissue Regeneration

Immunology

Published on 2022-01-132022-11-01
Journal: Frontiers in Immunology [Category] COVID-19,

[키워드] “cytokine storm” affected Alter Analysis biological function bronchoalveolar lavage sample CD40 Cell cell proliferation Cell therapy cell types chemotaxis clinical conditions Control COVID-19 COVID-19 patient Cytokine storm cytoplasmic Data analysis dispersion FHL2 Genes IFNGR1 IFNGR2 immune individual individuals induce inhibitor involved lung marker MDA5 mesenchymal stem cell Mild mild case mild COVID-19 patients MSC MSCs Necrosis NF-κB NFKBIA not express OPTN overexpression paracrine Patient performed PKR PPP2CB promote inflammation pulmonary receptors regeneration RNA secretion sequence Severe case severe COVID-19 single cell RNA sequencing single-cell RNA-seq STEM stem cell Target genes therapeutic therapeutic potential therapy for COVID-19 these cell tissue tlr-3 TLRs TNFR1 TNFR2 Transcription transcriptionally treat triggered upregulated upregulated gene upstream virus virus load
[DOI] 10.3389/fimmu.2021.780900 PMC 바로가기 [Article Type] Immunology

New Translational Trends in Personalized Medicine: Autologous Peripheral Blood Stem Cells and Plasma for COVID-19 Patient

Case Report

Published on 2022-01-102022-10-30
Journal: Journal of Personalized Medicine [Category] COVID-19,

[키워드] acute respiratory distress Allograft ARDS arterial blood gas (ABG) autologous autologous plasma and peripheral blood stem cells benefit Blood caused clinical biochemistry and molecular clinical biology Clinical stages Community coronavirus 2 country COVID-19 COVID-19 infection COVID-19 pandemic Critical death deaths disease effective Health Health authority ICU Inconclusive individual infected patient intensive care unit involved Italy Laboratory medicine MOF mortality rate multiple organ failure New Patient peripheral Peripheral blood plasma Protective antibody protocol reported respiratory SARS-CoV-2 Sepsis specific treatment STEM stem cell stem cells survivor Survivors syndrome the vaccine therapeutic Therapies thromboembolic to define Treatment trend Vascular
[DOI] 10.3390/jpm12010085 PMC 바로가기 [Article Type] Case Report

When stem cells meet COVID-19: recent advances, challenges and future perspectives

Review

Published on 2022-01-102022-10-29
Journal: Stem Cell Research & Therapy [Category] COVID-19, SARS,