the strongest – Page 5 – Communicable Diseases Research

Prevalence of comorbidity in Chinese patients with COVID-19: systematic review and meta-analysis of risk factors

중국 코로나19 환자의 동반질환 유병률: 위험인자에 대한 체계적인 검토 및 메타분석

Meta-Analysis

Published on 2021-02-222022-09-01
Journal: BMC Infectious Diseases
[Category] MERS, 진단,

Evaluating the effects of cardiometabolic exposures on circulating proteins which may contribute to severe SARS-CoV-2

심각한 SARS-CoV-2에 기여할 수 있는 순환 단백질에 대한 심혈관 대사 노출의 영향 평가

Research Paper

Published on 2021-02-032022-09-11
Journal: EBioMedicine
[Category] MERS, 바이오마커, 변종,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis antibody applied approach BMI body mass body mass index C-reactive protein cardiometabolic cardiometabolic exposure cardiometabolic risk factor Cardiometabolic risk factors caused circulating Circulating proteins conducted contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 disease COVID-19 progression COVID19 Critical cytokine Cytokines determine Developing disease Effect evaluate the effect Evaluating Evidence evidence of example finding foundation functions funding Future Genetic genomic location global pandemic glycoprotein heart help highlight host protein host response Immunoglobulin Immunoglobulin G independent Infection Inflammatory marker inflammatory markers Inflammatory response initial Innovation interleukin interleukin-6 involved IVW Medical Research Council mendelian randomization multiple testing Multivariable MR overcome Pathogenesis predicted progression proportion Protein provided raised receptor receptor antagonist replicate Research respiratory responsible risk risk factor Risk factors robust SARS-CoV-2 SARS-COV-2 infection sensitivity severe acute respiratory syndrome Coronavirus severe COVID-19 disease severe SARS severe SARS-CoV-2 smoking Standard deviation systemically the strongest Therapeutic strategies therapeutic strategy Triglyceride triglycerides turn variant variety Wellcome Trust
[DOI] 10.1016/j.ebiom.2021.103228 PMC 바로가기 [Article Type] Research Paper

Could COVID-19 anosmia and olfactory dysfunction trigger an increased risk of future dementia in patients with ApoE4?

COVID-19 후각 기능 장애와 ApoE4 환자에서 향후 치매 위험이 증가할 수 있습니까?

Article

Published on 2021-02-012022-09-11
Journal: Medical Hypotheses
[Category] 유전자 메커니즘,

[키워드] acute illness acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected Alzheimer's disease Anosmia APOE4 carriers Apolipoprotein Apolipoprotein e approved association best Brain carrier Central nervous system Complication coronavirus coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients Dementia disease dysfunction e4 allele early stage early stages genetic risk factor Haplotype Hypothesis identify increased risk increasingly Infection involved knowledge Lewy Bodies) load mechanism Modification nasal neurodegenerative neurological Neuropsychiatric olfactory olfactory dysfunction olfactory nerve open Patient question reported respiratory risk SARS-CoV-2 SARS-CoV-2. severe acute respiratory syndrome Coronavirus short duration speculation Stage subject Symptom Symptoms the strongest Therapies unique working hypothesis
[DOI] 10.1016/j.mehy.2020.110479 PMC 바로가기 [Article Type] Article

Oxygen metabolism markers as predictors of mortality in severe COVID-19

심각한 COVID-19에서 사망의 예측인자로서의 산소 대사 마커

Observational Study

Published on 2021-02-012022-09-11
Journal: International Journal of Infectious Diseases
[Category] MERS, SARS, 바이오마커, 임상,

[키워드] addition All participants Analysis ARDS arterial blood AUC Blood characteristic coronavirus disease Coronavirus disease 2019 COVID-19 Critically ill Critically ill patient critically ill patients cut-off cut-off point Deceased determinant Determinants of mortality had no healthy index individual marker medical record medical records metabolism Mortality oxygen Oxygen consumption Oxygen metabolism oxygen saturation oxygen) PaO partial pressure Participants Patient patients with COVID-19 predictor random number generator receiver operating characteristic respiratory Respiratory failure respiratory failure. respiratory index Retrospective analysis selected severe coronavirus disease severe COVID-19 Significant significant differences survivor Survivors the strongest venous venous blood was determined with COVID-19
[DOI] 10.1016/j.ijid.2020.12.012 PMC 바로가기 [Article Type] Observational Study

Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients

중환자 코로나19 환자의 혈장 사이토카인 수치 증가 및 장기 부전 및 30일 사망률과의 상관관계

Article

Published on 2021-02-012022-09-11
Journal: Cytokine
[Category] SARS, 바이오마커,

[키워드] 30-Day mortality abdominal surgery Acute kidney injury Admission Biomarkers Care caused Cohort controls Corona virus correlated correlation COVID-19 Critically ill critically ill COVID-19 patients cytokine cytokine expression cytokine response Cytokine storm Cytokine storm syndrome Cytokines death demonstrated expression IL-17A IL-1ra IL-4 IL-6 IL-8 increase increase in Increased induce Infection Inflammation inflammatory markers inflammatory mediator Inflammatory mediators Inflammatory response Informed consent initial symptoms intensive care Intensive care. IP-10 kidney Kidney injury MCP-1 median mediators moderate Mortality organ damage Organ failure Patient patients PCR-confirmed PCR-confirmed COVID-19 plasma Plasma cytokine plasma sample quantified Respiratory failure SARS CoV SARS CoV-2 SOFA score the strongest was obtained
[DOI] 10.1016/j.cyto.2020.155389 PMC 바로가기 [Article Type] Article

COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation

COVID-19 및 Toll-Like Receptor 4(TLR4): SARS-CoV-2는 TLR4에 결합하고 활성화하여 ACE2 발현을 증가시켜 진입을 촉진하고 과염증을 유발할 수 있습니다

Review

Published on 2021-01-142022-09-10
Journal: Mediators of Inflammation
[Category] 치료제,

[키워드] ACE2 activate Activation alveolar cell antagonist Antiviral appear ARDS bind binding cause causes causing Cell cell surface cells clinical trial contribute COVID-19 COVID-19 patients Cytokines decrease entry receptor Evidence expressed expression Facilitating heart failure hyperinflammation Immune cell immune cells include increase Infection Inflammation Injury innate immune innate immune response interferons lung Lungs Mortality multiorgan failure multiple-organ myocarditis PAMPs pathogen pathogen-associated molecular pattern pathogen-associated molecular patterns Pathogenesis pathogenesis of SARS-CoV-2 pathophysiological Proinflammatory cytokine proinflammatory cytokines promise protein-protein interaction Pulmonary surfactants receptor recognize reported Respiratory failure SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 spike glycoprotein secrete Sepsis severe COVID-19 significantly spike glycoprotein Spike protein surface tension tension the cell the SARS-CoV-2 the spike protein the strongest therapeutic target TLR4 Treatment Trigger triggers type I interferon type I interferons Viral Viral protein Viral proteins
[DOI] 10.1155/2021/8874339 PMC 바로가기 [Article Type] Review

Impact of population density and weather on COVID-19 pandemic and SARS-CoV-2 mutation frequency in Bangladesh

방글라데시에서 인구 밀도와 날씨가 COVID-19 전염병 및 SARS-CoV-2 돌연변이 빈도에 미치는 영향

Original Paper

Published on 2021-01-072022-09-11
Journal: Epidemiology and Infection
[Category] 변종,

The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2

SARS-CoV-2와 관련된 인간 폐의 노화 전사체 및 세포 경관

Article

Published on 2021-01-042022-09-10
Journal: Nature Communications
[Category] MERS, 유전자 메커니즘, 진단,

[키워드] age airway smooth muscle alveolar Analysis analysis basal cells Cell cells cellular change characterized contribute coronavirus coronavirus disease COVID-19 Data integration deconvolution analysis decrease dendritic cell dendritic cells dysregulated Endothelial cell endothelial cells Factor feature fibroblasts goblet cells human lung identify IGSF21 Immunogenetics in vitro lung Mitochondria Older Patient pericytes populations proportion proportions proteome reduced Replication responses reveal risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infection in vitro SARS-CoV-2 proteome severe coronavirus disease severe COVID-19 severity of COVID-19 smooth muscle Stress stress responses the SARS-CoV-2 the strongest transcriptional transcriptionally Transcriptome transcriptomes viral infection
[DOI] 10.1038/s41467-020-20323-9 PMC 바로가기 [Article Type] Article

The spread of SARS-CoV-2 in Spain: Hygiene habits, sociodemographic profile, mobility patterns and comorbidities

스페인의 SARS-CoV-2 확산: 위생 습관, 사회인구학적 프로필, 이동 패턴 및 동반 질환

Article

Published on 2021-01-012022-09-11
Journal: Environmental research
[Category] SARS, 치료기술,

[키워드] analyzed bleaching chose Comorbidities Comorbidity conducted confinement Contagion COVID-19 COVID-19 patient Critical critical points detect Disinfection dogs effective Effectiveness Ethanol exposure to hygiene increase in increased the risk market Masks measure Measures Metro Mobility modality pandemic Pandemics Prevalence prevention strategies public health reduce reduced reducing risk Risk factors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2. shown Sociodemographic Sociodemographic characteristics Spain Spanish Spread the disease the strongest Transmission variable virus wearing masks Workplace
[DOI] 10.1016/j.envres.2020.110223 PMC 바로가기 [Article Type] Article

Correlation between laboratory parameters on admission and outcome of COVID-19 in maintenance hemodialysis patients

유지 혈액 투석 환자에서 입원에 대한 실험실 매개 변수와 COVID-19의 결과 사이의 상관 관계

Comparative Study

Published on 2021-01-012022-09-11
Journal: International urology and nephrology
[Category] SARS, 바이오마커,

[키워드] Admission age albumin Analysis AUC blood cell C-reactive protein Clinical data clinical evaluation Clinical outcome collected coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus pneumonia COVID-19 CRP disease evaluate fatality general condition groups Hemodialysis hospital infected with COVID-19 Intervention Laboratory laboratory parameter Laboratory parameters Lactate lactate dehydrogenase LDH Maintenance hemodialysis Measures neutrophil neutrophil count novel Novel coronavirus novel coronavirus pneumonia Novel coronavirus pneumonia. on admission outcome parameter Patient patients patients with COVID-19 Pneumonia Predictive procalcitonin Prognosis receiver operating characteristic Retrospective analysis ROC significant difference survival group the patient the strongest was performed was used White blood cell white blood cell count
[DOI] 10.1007/s11255-020-02646-0 PMC 바로가기 [Article Type] Comparative Study