Distinguishing SARS-CoV-2 bonafide re-infection from pre-existing minor variant reactivationSARS-CoV-2 보나파이드 재감염과 기존의 마이너 변이체 재활성화 구별Case Reports Published on 2021-06-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] MERS, SARS, 바이오마커, 변종, 치료기술, [키워드] Analysis complex interplay Consensus Course disease distinguishing event evidenced explained FIVE Frequency group highlight Infection Intrahost variation Multiple Multiple infection National Cancer Institute new virus Next-generation sequencing nucleotide observation Patient PCR amplification PCR tests Population Re-infection Reactivation Reinfection reported RT-PCR tests SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 sequence SARS-CoV-2 sequences sequence sequenced Single nucleotide variant SNV SNVs timepoint variant variants Viral viral reactivation viral shedding virus viruses [DOI] 10.1016/j.meegid.2021.104772 PMC 바로가기 [Article Type] Case Reports
Exploring the Impact of COVID-19 Response on Population Health in Saudi Arabia: Results from the “Sharik” Health Indicators Surveillance System during 2020Article Published on 2021-05-162022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] activities adjusted odds ratio age Analysis AOR Cancer change chronic disease Chronic diseases chronic respiratory diseases conducted continuous monitoring COVID-19 cross-sectional demographic data diabete diabetes disease Effect Evidence exhibited female Health hypertension Impact increases in Indicator Mortality Participants physical activity Population Population health potential participant Prevalence Prevent reductions in Region response Result risk factor Risk factors Saudi Arabia significant increase significant increases in Significant reduction stroke Surveillance System timepoint [DOI] 10.3390/ijerph18105291 PMC 바로가기 [Article Type] Article
covid19census: U.S. and Italy COVID-19 metrics and other epidemiological dataOriginal Article Published on 2021-05-152022-11-01 Journal: Database: The Journal of Biological Databases and [Category] COVID-19, SARS, [키워드] can be used confirmed case coronavirus COVID-19 COVID-19 mortality deaths diabete Effects epidemiological epidemiological data estimate function functions heterogenous Italy Metrics morbidity and mortality offer other variable outcomes pandemic R package Repository researcher resources the disease timepoint USA utility variable variables [DOI] 10.1093/database/baab027 PMC 바로가기 [Article Type] Original Article
Maternal depressive and anxiety symptoms before and during the COVID-19 pandemic in Canada: a longitudinal analysisObservational Study Published on 2021-05-012022-10-05 Journal: The lancet. Psychiatry [Category] Fulltext, SARS, 임상, [키워드] 95% CI Anxiety anxiety symptom Canada center changes in clinically Cohort collected Comparisons Complete COVID-19 COVID-19 pandemic cross-sectional cross-sectional analysis demonstrated Depression depression score depressive depressive symptom eligible estimate estimates family financial support Follow-up foundation greater health-care increases in individual level inventory key priority longitudinal analysis Maternal mental health problem mother parent Pregnancy Prevalence proportion Psychological distress Regression model Research Schools solution Symptom team timepoint timepoints were assessed were excluded white women [DOI] 10.1016/S2215-0366(21)00074-2 PMC 바로가기 [Article Type] Observational Study
Parents Are Stressed! Patterns of Parent Stress Across COVID-19Psychiatry Published on 2021-04-082022-10-31 Journal: Frontiers in Psychiatry [Category] COVID-19, [키워드] activity analysis of variance caused changes in children common contribute coronavirus COVID-19 Deleterious described effective strategy elevated examined female Health impacted Intervention long-lasting measure mental health mitigate MOST pandemic parent parent coping parenting stress parents pattern Perceived Stress Scale PSS Public question remained reported resource retrospective returned Stress Stress management Stressor survey timepoint viral pandemic [DOI] 10.3389/fpsyt.2021.626456 PMC 바로가기 [Article Type] Psychiatry
Invasive pulmonary aspergillosis in critically ill patients with severe COVID-19 pneumonia: Results from the prospective AspCOVID-19 study중증 COVID-19 폐렴이 있는 중환자의 침습성 폐 아스페르길루스증: 전향적 AspCOVID-19 연구 결과Research Article Published on 2021-03-172022-09-10 Journal: PLoS ONE [Category] SARS, 치료기술, [키워드] affected age Analysis APACHE II score approach both groups bronchial lavage clinical parameter Clinical parameters Cohort collected Combination Complication controls COVID-19 COVID-19 cohort COVID-19 pneumonia Critically ill Critically ill patient critically ill patients defined diagnosed diagnostic early stage evaluate finding galactomannan help high mortality rate ICU ICU admission identify incidence invasive Invasive pulmonary aspergillosis IPA Laboratory Logistic regression Logistic regression analyses matched controls mechanical ventilation median Mortality not different outcome Patient Pneumonia prevalent pulmonary aspergillosis regression analysis Result risk factor Risk factors screened severe COVID-19 Severe COVID-19 pneumonia severe viral pneumonia Study protocol timepoint Viral Viral pneumonia Virological [DOI] 10.1371/journal.pone.0238825 PMC 바로가기 [Article Type] Research Article
Longitudinal SARS-CoV-2 antibody study using the Easy Check COVID-19 IgM/IgG™ lateral flow assayEasy Check COVID-19 IgM/IgG™ lateral flow assay를 사용한 종방향 SARS-CoV-2 항체 연구Research Article Published on 2021-03-042022-09-12 Journal: PLoS ONE [Category] SARS, 진단, [키워드] anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgM antibody Antibody Response check collected COVID-19 decrease detect determine Disease progression Donor Efficacy Evidence IgG antibodies IgG antibody IgM antibody IgM antibody levels immune response immune responses initial lateral flow Longevity longitudinal MONITOR Novel coronavirus novel coronavirus SARS-CoV-2 Pathogenesis Patient patients PCR-confirmed COVID-19 patient plasma sample plasma samples post-symptom onset Protective PSO Re-infection required researcher Result SARS-CoV-2 SARS-CoV-2 antibody Seroconversion shift sustained tested the antibody response timepoint Treatment strategies Vaccine Vaccine development [DOI] 10.1371/journal.pone.0247797 PMC 바로가기 [Article Type] Research Article
Inclusion of pregnant women in COVID-19 treatment trials: a review and global call to actionCOVID-19 치료 시험에 임산부 포함: 검토 및 글로벌 행동 촉구Review Published on 2021-03-012022-09-11 Journal: The Lancet. Global health [Category] Fulltext, SARS, 임상, 치료법, [키워드] Chloroquine Clinical treatment clinical trial clinical trial registry clinical trials Corticosteroids COVID-19 criterion drug during pregnancy effective effective therapy evaluated excluded exclusion Health High-dose Hydroxychloroquine identify IMPROVE Inclusion interferon beta International Ivermectin Lopinavir Lopinavir-ritonavir outcomes Pregnancy pregnant women proportion recommendation Remdesivir Ritonavir timepoint Treatment treatment for COVID-19 treatment trial treatment trials Trial Vitamin [DOI] 10.1016/S2214-109X(20)30484-8 PMC 바로가기 [Article Type] Review
Impact of intravenous lidocaine on clinical outcomes of patients with ARDS during COVID-19 pandemia (LidoCovid): A structured summary of a study protocol for a randomised controlled trialCOVID-19 대유행 중 ARDS 환자의 임상 결과에 대한 정맥내 리도카인의 영향(LidoCovid): 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-02-112022-09-10 Journal: Trials [Category] MERS, 임상, [키워드] 1:1 24 hour 24 hours acute renal failure acute respiratory distress acute respiratory distress syndrome Admission adverse event adverse events age albumin All participant All participants Anti-inflammatory effects approved aPTT ARDS Atrial fibrillation Bacterial Berlin Beta Bicarbonate biological sample biological samples blinded Blinding blockers blood count bolus bronchospasm cardiac rhythm Cardiogenic shock Care care providers Child bearing clinical Clinical data Clinical outcome clinical study collected Commission comparator complete blood count Complication computer-generated Concentration conducted Consumption control group cough COVID-19 COVID-19 pneumonia Covid-19 subgroup CRP D-dimers delirium diagnostic Disease progression disorders dissemination distribution Distribution ratio dosage Effect element ethics committee evaluate the effect evaluated Evolution experimental group extubation ferritin fibrinogen FiO2 followed by following form France French Gas exchange HCG Hospitalized hypnotics ICU IL-6 Ileus Impact incidence include inclusion criteria Inflammation Inflammatory marker inflammatory markers intensive care intensive care unit interval intervention group intravenous Intubated investigator LDH Length lidocaine Local local anaesthetics Local anesthetics Lymphocytes moderate moderate to severe Modification molecular mechanisms of pharmacological action Mortality NaCl number objective Older opioids outcome Pandemia PaO2 PaO2/FiO2 ratio parallel group participant Patient patients with ARDS PCT Phase 3 Placebo placebo-controlled Platelets Pneumonia pneumopathy Pneumothorax Prevent Primary outcome protection Protective protocol QTc random randomisation randomised randomised controlled trial randomize Randomized Randomly receive Recovery time recruitment Registered Renal Dialysis renal failure report respiratory distress RT-PCR Sample size SARS-CoV2 infection secondary endpoint Secondary endpoints sedated Severe acute respiratory syndrome severe ARDS Shock Social Security Social security system sore throat status Stratification stroke Study protocol supplementary material surgical syndrome tetraplegia thromboembolic Thromboembolic event timepoint Toxicity Treatment Trial Trial registration triglycerides troponin two group two groups university vasopressors Ventilation ventilator ventilator-free day Ventilator-free days website women written Informed Consent [DOI] 10.1186/s13063-021-05095-x PMC 바로가기 [Article Type] Letter
Navigating the Quagmire: Comparison and Interpretation of COVID-19 Vaccine Phase 1/2 Clinical TrialsReview Published on 2020-12-092022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] adverse event adverse events antibody Antibody titers assays candidate clinical Clinical outcome clinical trials comparison COVID-19 Critical Determination Efficacy follow-up time harmonization highest immunogenicity methodological nine outcome outlined pandemic phase phase 3 trial Phase 3 trials profile Protective public health response robust SARS-CoV-2 Serious Adverse Event Study design the vaccine timepoint Vaccine Vaccines Variation [DOI] 10.3390/vaccines8040746 PMC 바로가기 [Article Type] Review