Optimizing use of theranostic nanoparticles as a life-saving strategy for treating COVID-19 patientsReview Published on 2020-05-012022-10-28 Journal: Theranostics [Category] COVID-19, MERS, SARS, [키워드] addition administration approved benefit carrier caused cells clinical trial Concentration coronavirus 2 COVID-19 disease drug drug delivery systems drugs effective expected globe help immune indication Infection Infectious disease intranasal investigated mucosal nanomedicine noninvasive offer overcome peptide pulmonary diseases reported respiratory SARS-CoV-2 Side effect SIREN siRNA specific treatment theranostic nanoparticles therapeutic therapeutic agent treating COVID-19 patient Treatment response Vaccines while World Health Organization [DOI] 10.7150/thno.46691 PMC 바로가기 [Article Type] Review
CT Scans of Patients with 2019 Novel Coronavirus (COVID-19) PneumoniaResearch Paper Published on 2020-03-152022-10-28 Journal: Theranostics [Category] COVID-19, MERS, [키워드] 2019 novel coronavirus change China Clinical characteristics Clinical outcome Clinical treatment COVID-19 COVID-19 pneumonia CT scan defined died discharged evaluate Features follow up Follow-up help hospital Hospital stay investigated median MOST novel outcome outcomes Patient Pneumonia progressed progression remained response Risk factors single-center study Symptom Treatment Treatment response [DOI] 10.7150/thno.45016 PMC 바로가기 [Article Type] Research Paper
CD4+ T Cell Recovery and Hepatitis B Virus Coinfection in HIV-Infected Patients from Côte d’Ivoire Initiating Antiretroviral TherapyRandomized Controlled Trial Published on 2018-05-012023-06-16 Journal: AIDS research and human retroviruses [Category] B형 간염, [키워드] Antiretroviral therapy immune restoration sub-Saharan Africa Treatment response viral replication. [DOI] 10.1089/AID.2017.0272 PMC 바로가기 [Article Type] Randomized Controlled Trial
Predictive role of serum HBsAg and HBcrAg kinetics in patients with HBeAg-negative chronic hepatitis B receiving pegylated interferon-based therapyRandomized Controlled Trial Published on 2018-03-012023-06-19 Journal: Clinical microbiology and infection : the official [Category] B형 간염, [키워드] cccDNA. Chronic Hepatitis B HBcrAg HBsAg Hepatitis B core-related antigen Hepatitis B virus Pegylated interferon predictor stopping rule Treatment response [DOI] 10.1016/j.cmi.2017.07.016 PMC 바로가기 [Article Type] Randomized Controlled Trial
Telbivudine therapy for chronic hepatitis B: A journey to identify super-responders and to optimize treatment using the roadmap modelReview Published on 2017-01-012023-06-18 Journal: Journal of gastroenterology and hepatology [Category] B형 간염, [키워드] Hepatitis B virus infection nucleos(t)ides analogs prediction Treatment response Viral load. [DOI] 10.1111/jgh.13512 PMC 바로가기 [Article Type] Review
Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases기능성 IL6R 358Ala 대립유전자는 전통적인 IL-6 수용체 신호 전달을 손상시키고 다양한 염증성 질환의 위험에 영향을 미칩니다Research Article Published on 2013-04-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] 358Ala Abdominal aortic aneurysm affecting allele analyzed aortic aneurysm approach Arthritis Asp358Ala association Asthma Atrial fibrillation Author balance benefit Cambridge BioResource causal variant CD4+ T cell CD4+ T cells CHD Chronic diseases circulating cleavage clinical trial clinical trials common diseases complex complex diseases Concentration Control copy Coronary heart disease Critical cytokine diabete diabetes etiology Evidence expression functional Genetic genetic association Genetic variation heart disease human disease identify IL-6 IL-6 receptor IL-6 signaling IL-6R IL-6R signaling IL-6R signaling pathway IL6R Immune cell immune cells impairment implicated implication increase increase in independent Inflammatory Inflammatory responses influence interleukin interleukin-6 isoform mechanism membrane-bound molecular mechanism monocyte Monocytes mononuclear cell mononuclear cells Non-synonymous nucleotide Patient PBMCs Peripheral blood Peripheral blood mononuclear cells Phosphorylation polymorphism Population protein level protein levels RA reduce reduced reduction regulated Regulation rheumatoid arthritis risk rs2228145 Signaling sIL-6R single nucleotide Single nucleotide polymorphism soluble IL-6R Stat1 STAT3 Stimulation suggested surface expression surface receptor susceptibility T cells T1D therapeutic intervention therapy These data Transcription transcription factor transcription factors translate Treatment response Type 1 diabetes variant Variation Volunteer [DOI] 10.1371/journal.pgen.1003444 PMC 바로가기 [Article Type] Research Article