virus variants – Page 5 – Communicable Diseases Research

Mitigating Covid-19 in the face of emerging virus variants, breakthrough infections and vaccine hesitancy

새로운 바이러스 변종, 획기적인 감염 및 백신 주저에 직면하여 Covid-19 완화

Review

Published on 2022-02-012022-09-11
Journal: Journal of autoimmunity [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial

보조제 서브유닛 단백질 COVID-19 백신, SCB-2019의 효능: 2상 및 3상 다기관, 이중 맹검, 무작위 배정, 위약 대조 시험

Clinical Trial

Published on 2022-01-292022-09-11
Journal: Lancet (London, England) [Category] 변종, 임상,

[키워드] 1:1 95% CI alum assigned baseline Belgium biopharmaceutical Brazil caused chloride circulating Clover Coalition country COVID 19 COVID-19 COVID-19 case COVID-19 vaccine CpG Cutoff dose doses double-blind effective vaccine Effective vaccines Efficacy efficacy analysis elicited Endpoint enrolled EudraCT exclusion FIVE follow-up period groups Health health condition injection injection site pain intramuscular dose Local median Mild-to-moderate moderate-to-severe COVID-19 MOST multicentre notable Older pandemic participant per-protocol per-protocol population Phase 2 Placebo placebo recipients placebo-controlled trial predominant primary endpoints Protein provide randomisation randomised Randomly receive Registered RT-PCR Safe SAR-CoV-2 SARS CoV SARS-CoV-2 SCB-2019 second dose seronegative participant Seropositivity severe COVID-19 severity Sodium chloride South Africa subset subunit systemic adverse event systemic adverse events Vaccine vaccine efficacy vaccinee vaccinees variant virus virus variants viruses was done
[DOI] 10.1016/S0140-6736(22)00055-1 PMC 바로가기 [Article Type] Clinical Trial

The Petasites hybridus CO 2 Extract (Ze 339) Blocks SARS-CoV-2 Replication In Vitro

Article

Published on 2022-01-072022-10-28
Journal: Viruses [Category] COVID-19, SARS,

International Nonproprietary Names (INN) for novel vaccine substances: A matter of safety

새로운 백신 물질에 대한 INN(International Nonproprietary Names): 안전성 문제

Review

Published on 2022-01-032022-09-11
Journal: Vaccine [Category] SARS, 변종,

[키워드] applicability assigned Biological Biological Standardization Committee COVID-19 COVID-19 pandemic criteria ENhance exchange expert explain facilitate Health Organization inactivated information ingredient International Nonproprietary Names live-attenuated vaccine live-attenuated vaccines mRNA vaccines name novel Novel vaccine substances novel vaccines nucleic acid nucleic acids patient safety pharmacovigilance recipients Recombinant protein recombinant proteins Safe SARS-CoV-2 SARS-CoV-2 vaccine the WHO Traditional unique Vaccine Vaccines Viral vector vaccines virus variant virus variants WHO World Health Organization
[DOI] 10.1016/j.vaccine.2021.11.054 PMC 바로가기 [Article Type] Review

Neutralization of SARS-CoV-2 requires antibodies against conformational receptor-binding domain epitopes

SARS-CoV-2의 중화에는 구조적 수용체 결합 도메인 에피토프에 대한 항체가 필요합니다

Article

Published on 2022-01-012022-09-11
Journal: Allergy [Category] SARS, 변종, 진단,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antibody antibody repertoire Antibody Response Antibody responses clinically conformational conformational epitopes coronavirus correlated COVID-19 Critical determinant determinants domain effective vaccine Effective vaccines epitope Epitopes exposure to humoral immune response IgG IgG antibodies IgG antibody Immunity immunization Immunoglobulin Immunoglobulin G increasingly induce likelihood Mild natural infection Neutralizing antibodies Patient peptide peptide epitope peptide epitopes peptides polyclonal polyclonal antibody Prevent Protective protective immunity RBD RBD binding RBD-specific IgG receptor Receptor-binding domain required respiratory SARS-CoV-2 SARS-CoV-2 proteins SARS-CoV-2-neutralizing antibodies SARS-CoV-2-neutralizing antibody sera severe acute respiratory syndrome Coronavirus severe COVID-19 Spike protein sterilizing immunity suppression the receptor-binding domain the SARS-CoV-2 vaccination Vaccine Vaccines variant virus Virus neutralization virus variants virus-neutralizing
[DOI] 10.1111/all.15066 PMC 바로가기 [Article Type] Article

SARS-CoV-2 infection among hospitalised pregnant women and impact of different viral strains on COVID-19 severity in Italy: a national prospective population-based cohort study

입원한 임산부의 SARS-CoV-2 감염과 이탈리아의 COVID-19 심각도에 대한 다양한 바이러스 균주의 영향: 국가 전향적 인구 기반 코호트 연구

Article

Published on 2022-01-012022-09-11
Journal: BJOG : an international journal of obstetrics and [Category] SARS, 변종,

[키워드] 95% CI Admission age Asymptomatic Birth rate citizenship clinician Cohort Cohort studies Comorbidity country COVID-19 COVID-19 disease COVID-19 illness COVID-19 pneumonia COVID-19 severity death described Hospital admission hospitalised hospitals ICU ICU admission intensive care intensive care unit Italian Italy Maternal maternal age Migration mode multivariate analyses National Neonatal Neonatal Mortality obesity Occurrence outcome outcomes Pneumonia population-based cohort Pregnancy pregnant women Preterm birth prospective cohort study remained reported required Research risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral severe COVID-19 disease severe COVID-19 illness severity significant increase Stillbirth strain ventilatory support viral strain virus variant virus variants wild-type women
[DOI] 10.1111/1471-0528.16980 PMC 바로가기 [Article Type] Article

Iota-Carrageenan Inhibits Replication of SARS-CoV-2 and the Respective Variants of Concern Alpha, Beta, Gamma and Delta

Iota-Carrageenan은 SARS-CoV-2 및 우려되는 알파, 베타, 감마 및 델타의 각 변종 복제를 억제합니다

Article

Published on 2021-12-082022-09-10
Journal: International Journal of Molecular Sciences [Category] SARS, 변종, 치료제,

[키워드] age Alpha antiviral activity Antiviral effect Beta Calu Calu-3 can not carrageenan carrageenan types Carrageenans comparable concern contribute coronavirus COVID-19 COVID-19 pandemic Defense Delta effective exhibit Gamma human lung cell human lung cells independent independent of infect Infection inhibit investigated Iota iota-carrageenan kappa-carrageenan lack Lambda lambda-carrageenan lentivirus nasal Particle Prophylaxis pseudotyped pseudotyping public health threat reduce SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 spike Spread SSPL sulfated polymer sulfated polysaccharide sulfated polysaccharides supply the SARS-CoV-2 TMPRSS2 transgenic transmission of SARS-CoV-2 transmitted Treatment vaccination Vaccine Vaccine-induced immunity variants variants of concern Viral Viral transmission virulent virus variants VoC VOCs Wuhan
[DOI] 10.3390/ijms222413202 PMC 바로가기 [Article Type] Article

Raman Molecular Fingerprints of SARS‐CoV‐2 British Variant and the Concept of Raman Barcode

SARS -COV -2 영국 변형의 라만 분자 지문 및 라만 바코드의 개념

Research Article

Published on 2021-12-072022-09-01
Journal: Advanced Science [Category] SARS, 변종, 진단, 치료법,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affinity Amino acid antibody resistance barcode BOLD building Characteristics collected concept conformational coronavirus Coronavirus disease 2019 COVID‐19 detrimental diagnostic diagnostic sensitivity diagnostics facilitate fingerprint fingerprints fraction functional Host receptors hydrophobic hydrophobic interaction hydrophobic interactions information isomerism Japan Japanese molecular multiple mutation multiple mutations Mutation Nucleocapsid proteins phenol Protein purine purines pyrimidines Raman Raman spectroscopy respiratory RNA SARS‐CoV‐2 SARS‐CoV‐2 scrutiny secondary structures sensitivity severe acute respiratory syndrome Coronavirus spike and nucleocapsid proteins Spike proteins statistical sulfur Support translate tyrosine variant variants virus virus variant virus variants while
[DOI] 10.1002/advs.202103287 PMC 바로가기 [Article Type] Research Article

The rationale of ethanol inhalation for disinfection of the respiratory tract in SARS-CoV-2-positive asymptomatic subjects

SARS-COV-2- 양성 무증상 피험자에서 호흡기 소독을위한 에탄올 흡입의 이론적 근거

Perspectives

Published on 2021-12-042022-09-10
Journal: The Pan African Medical Journal [Category] MERS, SARS, 변종,

[키워드] acute respiratory syndrome coronavirus affecting antibody approach asymptomatic subject benefit carried carrier clinical trial contagious diseases coronavirus coronavirus 2 COVID-19 determine dimension drug Effect Efficiency Ethanol EtOH for disinfection Health health benefits Hypothesis identify individual inhalation Inhaled knowledge limit Local monoclonal antibodies nonspecific pandemic paper PAS positive problem public health rationale respiratory respiratory tract SARS-CoV-2 SARS-CoV-2 entry Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus 2 Support surgical the healthy therapeutic therapeutic window Toxicity treat Treatment virucidal virus variant virus variants
[DOI] 10.11604/pamj.2021.40.201.31211 PMC 바로가기 [Article Type] Perspectives

Vaccines and Vaccination against SARS-CoV-2: Considerations for the Older Population

Review

Published on 2021-12-042022-10-28
Journal: Vaccines [Category] COVID-19,