Substantial Decline in Use of HIV Preexposure Prophylaxis Following Introduction of COVID-19 Physical Distancing Restrictions in Australia: Results From a Prospective Observational Study of Gay and Bisexual MenObservational Study Published on 2021-01-012022-10-05 Journal: Journal of acquired immune deficiency syndromes (1 [Category] 임상, [키워드] 95% CI 95% confidence interval adjusted odds ratio age Binary logistic changes in cohort study Coverage COVID-19 Decline Discontinuing dosing regimen fluctuation gay HIV HIV infection HIV-negative Impact information introduced investigated less men Multiple regression novel coronavirus disease pandemic participant physical distancing preexposure prophylaxis Prospective public health public health measures questionnaire reduced reduction in reported restriction Result risk Sex tested was used [DOI] 10.1097/QAI.0000000000002514 PMC 바로가기 [Article Type] Observational Study
Aspergillosis Complicating Severe Coronavirus Disease심각한 코로나바이러스 질병을 복잡하게 만드는 아스페르길루스증Review Published on 2021-01-012022-09-10 Journal: Emerging Infectious Diseases [Category] MERS, SARS, 치료기술, [키워드] abnormality airway aspergillosis Aspergillus Case series case sery classic clearance Combined complications constellation coronavirus coronavirus disease COVID-19 Diagnosis disease epithelial Europe fungal infections fungi Immunocompromised Immunosuppression IMPROVE increasingly Influenza influenza infection invasive killing Lung disease neutropenia outcome outcomes Pathologies pathophysiology Patient Prospective pulmonary aspergillosis respiratory infections risk SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 severe viral pneumonia syndrome therapy Viral viral infection viral infections virus zoonoses [DOI] 10.3201/eid2701.202896 PMC 바로가기 [Article Type] Review
Six-Month Pulmonary Impairment after Severe COVID-19: A Prospective, Multicentre Follow-Up StudyObservational Study Published on 2021-01-012022-10-05 Journal: Respiration [Category] 임상, [키워드] 6-min walking test Abnormalities acute respiratory syndrome administration age airway Asthma caused chest imaging chest X-ray collected Comorbidity coronavirus coronavirus disease COVID-19 defined Diagnosis diffusion capacity discharge Dyspnoea enrolled Follow-up functional Future highest Hospitalization identify impairment interquartile range invasive logistic regression model Lung disease median Medical Research Council mMRC MONITOR multicentre observation Observational cohort study parameter Patient patients patients hospitalized Physical examination Pneumonia positive Prophylactic Prospective protective factor pulmonary pulmonary fibrosis radiological radiology Radiology and other imaging reported Respiratory function tests SARS-CoV-2 SARS-CoV-2 pneumonia stratified ventilatory ventilatory support [DOI] 10.1159/000518141 PMC 바로가기 [Article Type] Observational Study
Prospective Sero-epidemiological Evaluation of SARS-CoV-2 among Health Care Workers in a German Secondary Care Hospital독일 이차 치료 병원의 의료 종사자 중 SARS-CoV-2의 전향적 혈청 역학 평가Article Published on 2021-01-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus analyzed anti-SARS-CoV-2 anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies antibody Blood blood sample Blood samples Care cause Combination coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 detect Effectiveness enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay Epidemiology example HCW HCWs Health Health care health care facilities Health care system health care systems Health care worker Health status hospital hospitals hygiene IgG IgG antibodies IgG antibody Immunoglobulin Immunoglobulin G longitudinal study oropharyngeal swab pandemic participant Participants participated Prevalence prevalence of COVID-19 Prospective protocol protocols pulmonary disease respiratory RT-PCR RT-PCR testing SARS CoV SARS CoV-2 SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 virus secondary severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specific antibodies specific antibody Spread study period Study protocol sustainability the SARS-CoV-2 virus worker [DOI] 10.1016/j.ijid.2020.10.026 PMC 바로가기 [Article Type] Article
Effect of Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia: A Randomized Clinical TrialCOVID-19 폐렴으로 입원한 환자의 임상 악화에 대한 Tocilizumab 대 표준 치료의 효과: 무작위 임상 시험Randomized Controlled Trial Published on 2021-01-012022-09-12 Journal: JAMA Internal Medicine [Category] 임상, 진단, [키워드] 95% CI age benefit blinded C-reactive protein causes clinical Clinical Center control arm control group coronavirus disease COVID-19 criteria death defined died Disease progression Effect elevated EudraCT evaluate evaluate the effect experimental arm experimental group Fever fraction groups hospital Hospitalized inflammatory phenotype intensive care Intention-to-treat analyses interim analysis interquartile range intravenous tocilizumab Intubated Invasive mechanical ventilation Italy less majority male median Nasopharyngeal swab NCT04346355 Open-label outcome oxygen pandemic Patient patients hospitalized patients with COVID-19 placebo-controlled Pneumonia polymerase chain Prospective protocol radiologic imaging randomization Randomized randomized clinical trial randomized patient receive Retrospective study safety profile second dose shown Stage Standard standard care standard care group Standard of care Standard therapy supportive care the disease therapy Tocilizumab tocilizumab administration Trial Two patient with COVID-19 worsening [DOI] 10.1001/jamainternmed.2020.6615 PMC 바로가기 [Article Type] Randomized Controlled Trial
A prospective multicentre external validation study of the Liverpool Peritonsillar abscess Score (LPS) with a no-examination COVID-19 modification비검사 COVID-19 변형을 사용한 리버풀 복막 농양 점수(LPS)의 전향적 다기관 외부 검증 연구Multicenter Study Published on 2021-01-012022-09-11 Journal: Clinical otolaryngology : official journal of ENT- [Category] SARS, 변종, [키워드] abscess Accuracy AUROC calculated COVID-19 COVID-19 pandemic Diagnosis Dysphagia External external validation independent indicate LPS Modification modify multicentre Negative predictive value NPV oral examination outcome patient cohort Peritonsillar Peritonsillar abscess Positive predictive value PPV Predictive value Prospective receiver operating characteristic referred to ROC score secondary care Sensitivity and specificity sore throat specificity Support swallowing swallowing. tonsillitis United Kingdom variant [DOI] 10.1111/coa.13652 PMC 바로가기 [Article Type] Multicenter Study
Significantly Decreased Mortality in a Large Cohort of Coronavirus Disease 2019 (COVID-19) Patients Transfused Early with Convalescent Plasma Containing High-Titer Anti-Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein IgG고역가 항중증급성호흡기증후군 코로나바이러스 2(SARS-CoV-2) 스파이크 단백질 IgG를 포함하는 회복기 혈장으로 조기에 수혈된 환자Article Published on 2021-01-012022-09-12 Journal: The American journal of pathology [Category] SARS, 진단, [키워드] aggregate Analysis Anti-RBD IgG Anti-spike authorization Cohort Containing convalescent plasma coronavirus 2 Coronavirus disease 2019 COVID-19 COVID-19 patient Cutoff decrease Decreased drug early treatment Emergency enzyme-linked immunosorbent facilitated Follow-up food highest Hospitalization hospitalized COVID-19 patients hospitalized patients IgG interim analysis median Mortality Ortho Vitros Prospective Protein RBD RBD IgG Receptor binding domain reduce reported respiratory SARS-CoV-2 significantly spike therapy transfused [DOI] 10.1016/j.ajpath.2020.10.008 PMC 바로가기 [Article Type] Article
Prospective audit of breast cancer detection rates from 2WW referrals to a district general hospital during Covid-19 pandemicConference abstract Published on 2021-01-012022-10-05 Journal: European journal of surgical oncology : the journa [Category] 치료기술, [키워드] Breast cancer detection rate hospital pandemic Prospective [DOI] 10.1016/j.ejso.2020.11.048 [Article Type] Conference abstract
Practicality and Reliability of Self Vs Administered Rapid Geriatric Assessment Mobile AppObservational Study Published on 2021-01-012022-10-05 Journal: The journal of nutrition, health & aging [Category] 임상, [키워드] Administered aerobic age anorexia benefit Chronic illness Community components develop diagnostic domain fatigue frail frailty functional geriatric assessment Health identify illnesses Intervention likelihood ratio management Mobile Mobile application Negative predictive value NPV Older pandemic participant pathway performed platform positive Positive predictive value PPV Prevalence Prospective Rapid Rapid Geriatric Assessment reduce replacing reported Resilience rising risk SARC-F Screen self self-assessment sensitivity specificity syndrome weight loss [DOI] 10.1007/s12603-021-1672-9 PMC 바로가기 [Article Type] Observational Study
Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vaginal swabs of women with acute SARS-CoV-2 infection: a prospective study급성 SARS-CoV-2 감염 여성의 질 면봉에서 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 검출: 전향적 연구Article Published on 2021-01-012022-09-11 Journal: BJOG : an international journal of obstetrics and [Category] SARS, 치료기술, [키워드] acquisition acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 acute SARS-CoV-2 infection All study participants birth canal clinical disease clinician colonisation coronavirus detect detection determine diagnosed disease FIVE healthy hospitalised Infant Infection Medical conditions Mild Mild disease MOST nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs Neonatal Neonatal infection Neonate Neonates outcome participant passage pathogen Pathogens Patient perineum positive Pregnancy Prospective Prospective Study reproductive respiratory RT-PCR RT-PCR test SARS-CoV-2 SARS-COV-2 infection secretion severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 study participant Swab swabs time vagina Vaginal vaginal secretion. vaginal swab Viral woman women [DOI] 10.1111/1471-0528.16556 PMC 바로가기 [Article Type] Article