Efficacy of hydroxychloroquine for post-exposure prophylaxis to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among adults exposed to coronavirus disease (COVID-19): a structured summary of a study protocol for a randomised controlled trialLetter Published on 2020-06-032022-10-29 Journal: Trials [Category] COVID-19, SARS, [키워드] 1:1 access acute respiratory syndrome addition age anticipated assigned Asymptomatic Baltimore baseline blinded blocked Bone marrow Boston Care Chloroquine clinically suspected close contact Complete Compound Concomitant concomitant use conducted Contact coronavirus coronavirus disease cough COVID-19 criteria current Date defined determine Diagnosis disorder dissemination Efficacy element eligible eligible participant etiology excluded first dose HCQ Health care worker healthcare worker history Hospitalized household household contact Hydroxychloroquine hypersensitivity incidence index case Infection Intervention leukocyte Los Angele medication moderate multisite neutropenia New Orlean New York City number objective outcome participant PCR-confirmed Pharmacist polymerase chain polymorphonuclear Post-exposure prophylaxis Prevent Primary outcome prolonged exposure Prophylaxis protocol psoriasis randomised randomised controlled trial randomization Randomized receive receiving Registered registry renal impairment responders resulting Sample size SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR test Seattle Secondary objective Seven severe liver disease Shortness of breath statistical statistician stratified study drug study period Study protocol subjective fever syndrome Tamoxifen telehealth therapy Tolerability Treatment Trial Vaccine virus website women [DOI] 10.1186/s13063-020-04446-4 PMC 바로가기 [Article Type] Letter
An evidence mapping and analysis of registered COVID-19 clinical trials in ChinaResearch Article Published on 2020-06-012022-10-28 Journal: BMC Medicine [Category] COVID-19, SARS, [키워드] “COVID-19 2019 novel coronavirus Analysis antiviral drug antiviral drugs CCT Characteristics China Chinese clinical Clinical data clinical trial collected Control COVID-19 COVID-19 outbreak Critical current distributions division drugs evaluate evaluated Evidence experimental group Glaxo Hypothesis identify imperative information interquartile range Intervention majority median Medicine nucleic acid Patient performed pilot study platform primary endpoints Primary outcome Primary outcomes public health recruit Registered registry Research Result Sample size severity Smith Study design TCM the disease therapy Traditional Trial trials variety WHO WHO ICTRP [DOI] 10.1186/s12916-020-01612-y PMC 바로가기 [Article Type] Research Article
A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19Short communication Published on 2020-06-012022-10-05 Journal: Journal of critical care [Category] SARS, 치료법, [키워드] adhere approved article China Chloroquine clinical trial Clinical use consensus paper coronavirus coronavirus disease COVID-19 effective Effectiveness Efficacy and safety Emergency Evidence in vitro In-vitro indication International National Patient patients with COVID-19 Pneumonia public health emergency registry replication of SARS-CoV-2 Research Result Safety SARS-CoV-2 searched systematic review the disease Treatment Trial Unregistered virus World Health Organization [DOI] 10.1016/j.jcrc.2020.03.005 [Article Type] Short communication
Vaccines and Drug Therapeutics to Lock Down Novel Coronavirus Disease 2019 (COVID-19): A Systematic Review of Clinical TrialsInternal Medicine Published on 2020-05-282022-10-31 Journal: Cureus [Category] COVID-19, [키워드] 2019 novel coronavirus Antiviral approved BCG candidate cellular therapy Chinese Chloroquine clinical clinical trial Combination Compound conducted COVID 19 COVID-19 database deaths drug drug combination drug therapeutics effective healthcare ICTRP Infection information lock majority medication novel novel coronavirus disease observational study pandemic Phase I phase III trial registry responsible review sars-cov-2 (severe acute respiratory syndrome coronavirus -2) Stage tested therapeutic agent Therapeutics therapy Treatment treatment choices Trial Vaccine vaccine candidate Vaccines viral infection WHO [DOI] 10.7759/cureus.8342 PMC 바로가기 [Article Type] Internal Medicine
Review of trials currently testing treatment and prevention of COVID-19Systematic Review Published on 2020-05-232022-10-04 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 신약개발, 임상, 치료법, [키워드] Abstract age analysed Anti-inflammatory antivirals applied assist category Chinese clinical clinical trial clinical trials country COVID-19 COVID-19 case COVID-19 pandemic effort eligibility criteria European evaluated Evidence excluded Image immunomodulators Inclusion interquartile range Intervention investigated Major management median Novel coronavirus Numerous objective open label participant Patient care performed physician Pneumonia Potential treatment prevention prevention of COVID-19 promote Randomized Randomized controlled trial Registered registry Research researcher Result retrieved review SARS-CoV-2 searched Study design therapeutic Treatment Trial union withdrawn [DOI] 10.1016/j.cmi.2020.05.019 PMC 바로가기 [Article Type] Systematic Review
Psychological intervention on COVID-19 A protocol for systematic review and meta-analysis4900 Published on 2020-05-222022-10-30 Journal: Medicine [Category] COVID-19, MERS, [키워드] 95% confidence interval Admission adverse events calculated change Chinese CIs clinical clinical heterogeneity Cochrane Library cough COVID-19 database Dyspnea effective Effectiveness Effects Efficiency Evidence expressed GAD-7 Hamilton Anxiety Scale independent Infrastructure Intervention journal literature mean difference Meta-analysis Mild Non-invasive Novel coronavirus infection outcomes Patient PHQ-9 physical positive Primary outcomes protocol psychological condition Psychological intervention random effect model randomised controlled trial registry reported requiring supplemental oxygen researcher risk RT-PCR scale searched Secondary outcomes SMD standardized mean difference suggested systematic review time Treatment upper respiratory tract used to evaluate Web of Science WHO [DOI] 10.1097/MD.0000000000020335 PMC 바로가기 [Article Type] 4900
Patients with COVID-19 in 19 ICUs in Wuhan, China: a cross-sectional studyResearch Published on 2020-05-142022-11-01 Journal: Critical Care [Category] COVID-19, MERS, [키워드] Acute kidney injury age ARDS Chinese clinical Clinical characteristics clinical information Clinical management complications COVID-19 COVID-19 outbreak COVID-19 patient Critical care Critically ill patient critically ill patients cross-sectional Deceased disease ECMO Epidemic extracorporeal membrane oxygenation global pandemic higher risk hospital hospitals ICU ICU admission information Injury Intensive interquartile range Invasive mechanical ventilation investigated IQR Laboratory lymphocytopenia male mechanical ventilation median multicenter noninvasive occurred onset of symptom Organ failure Patient patients prospective observational study receive registry renal replacement therapy resource Result Septic shock severe complication spread of COVID-19 the patient treated vital signs with COVID-19 Wuhan Wuhan, China [DOI] 10.1186/s13054-020-02939-x PMC 바로가기 [Article Type] Research
Correlation between Heart fatty acid binding protein and severe COVID-19: A case-control studyResearch Article Published on 2020-04-292022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] all-cause mortality binding calculated case-control study chi-square test Chinese clinical confidence interval correlation COVID-19 determine diagnosed diagnosis of COVID-19 elevated fatty Features heart Hospital stay Hospitalization inclusion criteria marker Mild Patient patients predict progressed Protein Registered registry Result screened serum severe COVID-19 severity severity of COVID-19 tested the patient [DOI] 10.1371/journal.pone.0231687 PMC 바로가기 [Article Type] Research Article
China Registry of Hepatitis B (CR-HepB): Protocol and implementation of a nationwide hospital-based registry of hepatitis BObservational Study Published on 2020-03-012023-06-12 Journal: Scandinavian Journal of Public Health [Category] B형 간염, [키워드] hepatitis B real-world data registry [DOI] 10.1177/1403494818772188 [Article Type] Observational Study
Twenty Years of Targeted Treatment in Rheumatoid Arthritis in the Greek Databases: Achievements and Unmet NeedsCommentary Published on 2019-09-302024-09-02 Journal: Mediterranean Journal of Rheumatology [Category] 대상포진, [키워드] biologic agents registry rheumatoid arthritis spondylarthritis [DOI] 10.31138/mjr.30.3.141 PMC 바로가기 [Article Type] Commentary