Association between non‐alcoholic fatty liver disease with the susceptibility and outcome of COVID‐19: A retrospective studyOriginal Article Published on 2021-11-102022-10-29 Journal: Journal of Cellular and Molecular Medicine [Category] COVID-19, MERS, [키워드] age alanine aminotransferase Analysis Aspartate aminotransferase BMI body mass index C reactive protein collected data Comorbidities consequence coronavirus disease correlated COVID‐19 COVID‐19 patient COVID‐19 Cox regression diabete diagnosed disease elevated evaluate the effect events Evidence excessive alcohol consumption Fatty liver Gender General population Hospital stay hypertension incidence indicate Liver injury Mortality much higher NAFLD NAFLD patient non‐alcoholic fatty liver disease outcome Patient patients Prevalence proportion reported Retrospective study severity significant difference significantly higher susceptibility the patient viral shedding White blood cell [DOI] 10.1111/jcmm.17042 PMC 바로가기 [Article Type] Original Article
MEDTEC Students against Coronavirus: Investigating the Role of Hemostatic Genes in the Predisposition to COVID-19 SeverityArticle Published on 2021-11-092022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] MTHFR 95%CI acute respiratory syndrome ADAMTS13 Analysis association Association analysis Characteristics characterized clinical heterogeneity Cohort conducted Control coronavirus coronavirus disease COVID-19 COVID-19 severity database degree distribution Engineering evidenced extreme functions General population Genes Genetic Genetic predisposition Hemostasis Hemostatic hemostatic genes Host intrinsic investigated Italian Manifestations median Medicine Meta-analysis MTHFR MTR pandemic performed polygenic risk score polymorphism predicted predisposition PROC Regeneron risk role SARS-CoV-2 severe COVID-19 severe COVID-19 patient severity significantly single-nucleotide student susceptibility THBS2 the disease Thromboembolic events university variant virus with COVID-19 [DOI] 10.3390/jpm11111166 PMC 바로가기 [Article Type] Article
Candidate genes of SARS-CoV-2 gender susceptibilityArticle Published on 2021-11-092022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] acute respiratory syndrome ADAM10 Affect Analysis applied association bioinformatics BST2 candidate cascade CCR5 complement Computational biology and bioinformatics coronavirus COVID-19 disease Effect effective ENPEP evaluate expressed GATA1 Gender Genetic genetics gonadal host cell human protein immunology Infection initiated Interaction IRF1 IRF2 likelihood men molecular outcome ovarian pandemic Pathways performed reaction receptor signaling response SARS-CoV-2 SARS-CoV-2 treatment SERPING1 severity of symptoms Sex difference susceptibility target the SARS-CoV-2 tissue TLR4 TLR7 TMPRSS2 Topic understanding Variation women [DOI] 10.1038/s41598-021-01131-7 PMC 바로가기 [Article Type] Article
Predicted norovirus resurgence in 2021–2022 due to the relaxation of nonpharmaceutical interventions associated with COVID-19 restrictions in England: a mathematical modeling studyResearch Article Published on 2021-11-092022-10-28 Journal: BMC Medicine [Category] COVID-19, MERS, SARS, [키워드] assumption collected Community Contact coronavirus disease COVID-19 disease disease incidence Endemic England expected Government healthcare service hospital impacted incidence increase in Infection Infectious disease Intervention lifted mathematical Mathematical modelling National nonpharmaceutical intervention Norovirus NPI NPIs occur reduce reported Result seasonality supplementary material Surveillance susceptibility Transmission with COVID-19 [DOI] 10.1186/s12916-021-02153-8 PMC 바로가기 [Article Type] Research Article
Alamandine: Potential Protective Effects in SARS-CoV-2 Patients알라만딘: SARS-CoV-2 환자의 잠재적인 보호 효과Review Published on 2021-11-082022-09-10 Journal: Journal of the Renin-Angiotensin-Aldosterone Syste [Category] MERS, 치료제, [키워드] ACE2 acute respiratory distress acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alleviate angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Anti-inflammatory anti-inflammatory properties antithrombogenic benefit Cardiomyopathy Characteristics coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pathogenesis Effect fibrosis G protein-coupled receptor Health health benefits Hospitalization host cell host cells increase inhibit interstitial leads mortality rates occur outcome pathway pharmacological strategy physiological response Potential Prevent proinflammatory Protective pulmonary fibrosis RAS receptor reduce Renin renin-angiotensin system respiratory respiratory distress SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 patient severe acute respiratory syndrome Coronavirus severity Shock susceptibility systemic inflammatory thought Treatment upregulation [DOI] 10.1155/2021/6824259 PMC 바로가기 [Article Type] Review
Interplay between the genetics of personality traits, severe psychiatric disorders and COVID-19 host genetics in the susceptibility to SARS-CoV-2 infectionAcademic Psychiatry Published on 2021-11-072022-10-28 Journal: BJPsych Open [Category] COVID-19, [키워드] acute respiratory syndrome affecting association Cohort complex component contracting the virus coronavirus coronavirus disease correlation COVID-19 COVID-19 susceptibility Evidence examined Extraversion Genetic genetic risk genetic risk factor genetics Genome-wide association study GWAS Health higher risk highlight host genetics individual Interaction linkage Mental disorder Mental Disorders mental health overlapping pandemic Personality personality traits positive psychiatric disorder Psychiatric disorders reflected reported Result risk risk score SARS-CoV-2 SARS-COV-2 infection severe mental disorders severe psychiatric disorder susceptibility traits was used were used with COVID-19 [DOI] 10.1192/bjo.2021.1030 PMC 바로가기 [Article Type] Academic Psychiatry
COVID-19-associated mucormycosis presenting to the Emergency Department-an observational study of 70 patientsObservational Study Published on 2021-11-052022-10-05 Journal: QJM: An International Journal of Medicine [Category] SARS, 임상, [키워드] clinical feature collected COVID-19 COVID-19 disease COVID-19 infection COVID-19 symptom Department Diabetes Mellitus diagnosed Diagnosis diagnostic workup Emergency examination findings Final Fungal infection identify India interquartile males management median MOST Mucormycosis Patient presenting radiological retrospective risk factor Risk factors surgical susceptibility Symptoms systemic treated Treatment [DOI] 10.1093/qjmed/hcab190 PMC 바로가기 [Article Type] Observational Study
Gut Microbiota Interplay With COVID-19 Reveals Links to Host Lipid Metabolism Among Middle Eastern PopulationsMicrobiology Published on 2021-11-052022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] 16S rRNA 16S rRNA gene acute respiratory syndrome alteration Amino acid Analysis Anti-inflammatory Bacteria Bacteroide Biomarker both groups Butyrate carbohydrate changes in Community complex control group controls coronavirus COVID-19 COVID-19 disease severity ether Faecalibacterium function functional glycerophospholipid gut microbiota gut microbiota composition Host host cells increase in linoleic acid Lipid metabolic pathway metabolism microbial Microbiome microbiota middle non-infected P -value pathway performed Phylogenetic Population Replication SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2-infected individual severity Streptococcus subjects susceptibility [DOI] 10.3389/fmicb.2021.761067 PMC 바로가기 [Article Type] Microbiology
Transient Receptor Potential Vanilloid Subtype 1: Potential Role in Infection, Susceptibility, Symptoms and Treatment of COVID-19Medicine Published on 2021-11-042022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] agonist airways binding clearance COVID-19 COVID-19 patient domain down-regulate Effect epithelial cell Health Hypothesis impaired lung function imperative include Infection Inflammation kill knowledge mitigate motif New coronavirus novel other respiratory virus Pathogenesis pathophysiology Pollution Potential receptor role S protein SARS-CoV-2 SNPs subtype susceptibility Symptom Symptoms the disease therapeutic interventions therapy Transient translate Treatment TRPV TRPV-1 [DOI] 10.3389/fmed.2021.753819 PMC 바로가기 [Article Type] Medicine
COVID-19 Anosmia: High Prevalence, Plural Neuropathogenic Mechanisms, and Scarce Neurotropism of SARS-CoV-2?COVID-19 ANOSMIA : SARS-COV-2의 높은 유병률, 복수의 신경 병원성 메커니즘 및 부족한 신경 프로즘?Review Published on 2021-11-042022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus analyzed angiotensin angiotensin-converting enzyme 2 Anosmia apical surface appear causative pathogen cause Cell cellular Characteristics convalescent coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cytological damages examined expression in some Infection lack mechanism molecular nasal Nasal cavity neurons Neuropathology ODs olfactory olfactory bulb olfactory dysfunction Olfactory epithelium Pathogenesis Perspective Plural Prevalence priming protease receptor respiratory respiratory epithelium respiratory virus SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neurotropism SARS-CoV-2 receptor Serine severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Structure susceptibility target transmembrane serine protease transmembrane serine protease 2 underlie Viral viral infection [DOI] 10.3390/v13112225 PMC 바로가기 [Article Type] Review