Computational Investigation of Structural Dynamics of SARS-CoV-2 Methyltransferase-Stimulatory Factor Heterodimer nsp16/nsp10 Bound to the Cofactor SAMMolecular Biosciences Published on 2020-11-242022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] absence antiviral drug approved Area association binding binding mechanism Bound CAS caused characterized conformational contagious contribute coronavirus COVID-19 CoVs Dynamics electrostatic interaction ENCODE enzyme eukaryotic Factor highlight hotspot Hydrogen bond hydrophobic interaction identify identifying increase interactions investigated investigation Mechanics mechanism methyltransferase MM-PBSA MM/PBSA molecular dynamics Molecular dynamics simulation mRNA Mutagenesis mutants novel coronavirus disease Nsp16/nsp10 PCA Peptide inhibitor protein translation provide public health RNA stability S-adenosyl-L-methionine SAM SARS-CoV-2 scanning surface therapeutic agents thermodynamic Vaccine van der Waal virus was performed [DOI] 10.3389/fmolb.2020.590165 PMC 바로가기 [Article Type] Molecular Biosciences
COVID-19 Infection Process in Italy and Spain: Are Data Talking? Evidence From ARMA and Vector Autoregression ModelsPublic Health Published on 2020-11-232022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] affected ARMA model average calculated China Chinese Collapsing Contagion contagious coronavirus disease country COVID-19 decrease disease drastic Effect example Forecast Healthcare system help hospital Hospitalization ICU ICU-beds Infection intensive care Intervention Isolation Italy maintain measure Measures methodology Model national health system outbreak percentage predict Process reduce reduced reduction in regions resources Result significant increase similarity Spain Spread the patient These data vector vector-autorregression virulence virus [DOI] 10.3389/fpubh.2020.550602 PMC 바로가기 [Article Type] Public Health
Global strategies and effectiveness for COVID-19 prevention through contact tracing, screening, quarantine, and isolation: a systematic reviewReview Published on 2020-11-232022-10-28 Journal: Tropical Medicine and Health [Category] COVID-19, [키워드] approach article Asymptomatic benefit caused certainty of evidence CINAHL clinical trial registries Cochrane guideline Community conducted Contact tracing contagious Coverage COVID COVID-19 database deaths determine Effect effective Effectiveness emerging disease estimate Evidence global health globe Google Scholar Health incidence indicated Isolation measure mechanisms Model quarantine reduce reported reproductive Result risk of bia SARS-CoV-2 screened Screening screenings systematic review the epidemic through contact Treatment virus [DOI] 10.1186/s41182-020-00285-w PMC 바로가기 [Article Type] Review
Putative roles of vitamin D in modulating immune response and immunopathology associated with COVID-19Review Published on 2020-11-212022-10-04 Journal: Virus research [Category] SARS, 임상, 조류인플루엔자, [키워드] ACE-2 activate acute respiratory distress syndrome (ARDS) acute respiratory syndrome addition affected anti-inflammatory cytokines antimicrobial peptide bats cardiovascular system cause caused Cell chemokine China co-morbidity Concentration contagious coronavirus Coronavirus-2 COVID-19 COVID-19 case Critical Cytokine storm deficiency Dexamethasone died disrupting ecological ENhance entry of SARS-CoV-2 enzyme epithelial lining evaluate Evidence exaggerated immune response gastrointestinal tract global pandemic host cells Hypovitaminosis D immune evasion immune response immune responses immune system immunopathology incidence incidence of COVID-19 include increase Increased Infection intensive care unit investigated less lung Lungs Macrophage majority membranes MERS modulate modulating multiple mechanism organ pandemic pathogen pathogenesis of SARS-CoV-2 pleiotropic pro-inflammatory cytokine provide Randomized controlled trial receptor reduce reducing renin-angiotensin system replication of SARS-CoV-2 reported respiratory infection risk of COVID-19 SARS-CoV SARS-CoV-2 secretion Spread thought Travel Treatment urgency viral infection virus Vitamin Vitamin D with COVID-19 Wuhan zoonotic disease [DOI] 10.1016/j.virusres.2020.198235 PMC 바로가기 [Article Type] Review
Molecular characterization of isolated infectious bronchitis viruses from affected vaccinated broiler flocks in SyriaResearch Article Published on 2020-11-192022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] affected Broiler bronchitis Characteristics circulating contagious Continuous cross disease effective epidemiological genotyping IBV identity immunological protection induce Infectious Bronchitis Virus Intensive isolate lesion less limit Local molecular molecular characterization nucleotide passages pathogen performed PROTECT Research Result RT–PCR sequence Sequence analysis sequence similarity Sequencing serotype similarities Spread strain Syria targets the disease Vaccine vaccine strain variant viral isolate virus viruses [DOI] 10.1186/s12917-020-02672-1 PMC 바로가기 [Article Type] Research Article
Managing outbreaks of highly contagious diseases in prisons: a systematic reviewOriginal Research Published on 2020-11-162022-10-28 Journal: BMJ Global Health [Category] COVID-19, SARS, [키워드] Adenovirus approach approaches article Avian Influenza conducted Contact tracing contagious contagious disease contagious diseases country COVID-19 database disease Diseases disorders Effect Effectiveness epidemiological Evidence examined excluded Guidance Health implication infections infectious disease outbreak Influenza injuries investigation Isolation managing mumps outbreak Outbreaks peer-reviewed prevention strategies prison prisons public health Quantitative quarantine reported required Research response Result searched Seven Surveillance synthesis synthesised systematic review Transmission Tuberculosis varicella [DOI] 10.1136/bmjgh-2020-003201 PMC 바로가기 [Article Type] Original Research
Insights of COVID-19 pandemic impact on anesthetic management for patients undergoing cancer surgery in the National Cancer Institute, EgyptReview Published on 2020-11-112022-10-27 Journal: Ain-Shams Journal of Anesthesiology [Category] COVID-19, [키워드] Affect age airway manipulation anesthesiologist Cancer cancer patient clinical recovery co-morbidity complications contagious Course COVID-19 COVID-19 pandemic disease early phase groups healthcare worker higher risk Incubation period Infection insight management Mild National Cancer Institute New no symptoms not affect outbreak outcome pandemic Patient Prognosis protocol risk of infection the disease viral infection Viral load Virus Disease [DOI] 10.1186/s42077-020-00110-w PMC 바로가기 [Article Type] Review
An Update on Molecular Diagnostics for COVID-19COVID-19에 대한 분자 진단에 대한 업데이트Review Published on 2020-11-102022-08-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] Accuracy acute respiratory syndrome coronavirus affected affecting anatomical approach approaches arising assistance Asymptomatic carrier Asymptomatic carriers Care caused changed China Chinese patient Chinese patients Collecting Complete contagious contagious disease coronavirus coronavirus 2 coughing COVID-19 crisis CRISPR CRISPR-Cas12a Critical detect Diagnosis diagnostic diagnostic procedure diagnostic procedures diagnostics disease effective flu-like symptoms genome sequence house humans IgA IgG IgM imperative Infection Infectious disease lateral flow majority market Molecular diagnosis Other outbreak pandemic Particle pathogen pathogen detection Pathogens Patient POC Point positive respiratory Respiratory system reverse transcription-PCR RT-PCR SARS-CoV-2 scenario serum antibodies serum antibody severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe pneumonia SHERLOCK shown sneezing Spread Symptom Transmission virus widespread [DOI] 10.3389/fcimb.2020.560616 PMC 바로가기 [Article Type] Review
A Suggested Role of Human Growth Hormone in Control of the COVID-19 PandemicCOVID-19 전염병 통제에서 인간 성장 호르몬의 제안된 역할Endocrinology Published on 2020-11-092022-09-11 Journal: Frontiers in Endocrinology [Category] MERS, SARS, 치료기술, [키워드] affected aggressive course Behavior common factor contagious Control Coronavirus pandemic country Course COVID-19 deficiency distribution Early detection epidemiological Epidemiology females group growth hormone help hormone Human IGF-1 immune system leads life limitation male management morbidity morbidity and mortality observation patient groups patients planet question raised risk Risk factors role secretion Spread spread to the disease unique virus vulnerability worldwide pandemic Wuhan Wuhan, China [DOI] 10.3389/fendo.2020.569633 PMC 바로가기 [Article Type] Endocrinology
The Spatial Allocation of Hospitals With Negative Pressure Isolation Rooms in Korea: Are We Prepared for New Outbreaks?Original Article Published on 2020-11-082022-10-29 Journal: International journal of health policy and managem [Category] COVID-19, SARS, [키워드] acute respiratory syndrome addition allocation approach contagious country COVID-19 COVID-19 outbreak Critical disease distribution Epidemic evaluate Evidence Evidence-Based Health Policy examined Factor Geographic information system Government Health Facility Allocation healthcare facility highlight hospitals identify Infectious disease infectious disease outbreak information Isolation room Korean lack Middle East negative Negative pressure New novel coronavirus disease outbreak Outbreaks pressure provide public health resource respiratory diseases respiratory syndrome coronavirus reveal room South Korea Spread the disease threat Transmission urgency [DOI] 10.34172/ijhpm.2020.118 PMC 바로가기 [Article Type] Original Article