Dexamethasone – Page 51 – Communicable Diseases Research

Putative roles of vitamin D in modulating immune response and immunopathology associated with COVID-19

Review

Published on 2020-11-212022-10-04
Journal: Virus research [Category] SARS, 임상, 조류인플루엔자,

Early changes in immune cell subsets with corticosteroids in patients with solid tumors: implications for COVID-19 management

Immunotherapy Biomarkers

Published on 2020-11-202022-10-30
Journal: Journal for immunotherapy of cancer [Category] COVID-19, SARS,

[키워드] Absolute lymphocyte count absolute neutrophil count activated administration affected ALC ANC antiviral immunity antiviral responses Cancer CD4 cell CD8 cells cellular changes in Combination complex coronavirus Corticosteroid Corticosteroids COVID-19 Critical Cytometry Dexamethasone dose driving effective effector memory elevated enrolled Flow flow cytometry glucocorticoid High-dose hyperinflammation immune Immune cell Immunity immunomodulation Immunotherapy implication include increase in increased mortality Inflammation mediators Inflammatory lymphocyte lymphopenia management marker median Methylprednisolone Neutrophil-to-lymphocyte ratio NLR Patient Patients with cancer performed poor prognosis Prednisone reducing relative Result Retrospective analysis SARS-CoV-2 pandemic significant decrease significantly solid tumor statistically significant subset systemic inflammation T-lymphocytes therapy for COVID-19 Trial variety Wilcoxon signed-rank test
[DOI] 10.1136/jitc-2020-001019 PMC 바로가기 [Article Type] Immunotherapy Biomarkers

Activities of Serum Ferritin and Treatment Outcomes Among COVID-19 Patients Treated With Vitamin C and Dexamethasone: An Uncontrolled Single-Center Observational Study

Allergy/Immunology

Published on 2020-11-112022-10-31
Journal: Cureus [Category] COVID-19,

Sex differences in COVID-19: the role of androgens in disease severity and progression

COVID-19의 성별 차이: 질병 중증도 및 진행에서 안드로겐의 역할

Review

Published on 2020-11-112022-09-10
Journal: Endocrine [Category] MERS, SARS, 변종,

[키워드] affected androgen Androgen receptor Androgen receptors androgens CAG repeats children clinical trial condition COVID-19 COVID-19 disease COVID-19 disease severity COVID-19 progression COVID-19 treatment Critical Dexamethasone disease disease severity drug Evidence evidence of explain facilitate fatality help Hospitalization Host Hydroxychloroquine implicated Infection men morbidity Mortality nitric oxide outcome outcomes pandemic pathophysiology Pathways Patient percentage prepubertal progression promoter Prostate cancer protease receptor Result SARS-CoV2 SARS-CoV2 infection sensitivity Sensitivity test sensitivity tests Serine serine 2 sex hormone Sex hormones Spike proteins suggested Testosterone therapy TMPRSS2 Transcription transmembrane protease serine 2 Treatment variants Viral viral infectivity virus spike protein women
[DOI] 10.1007/s12020-020-02536-6 PMC 바로가기 [Article Type] Review

Toward Preparing a Knowledge Base to Explore Potential Drugs and Biomedical Entities Related to COVID-19: Automated Computational Approach

Original Paper

Published on 2020-11-102022-10-31
Journal: JMIR Medical Informatics [Category] COVID-19,

[키워드] 2019-nCoV Analysis applicability applied approach association automated base clinical status Community computational method confidence score coronavirus coronavirus disease COVID-19 deep learning Dexamethasone disease Diseases drug drug side effects drugs effective effective drug Effectiveness effort entity Evidence Genes help highlight human genes human miRNAs Hydroxychloroquine IMPROVE information Interaction Ivermectin labeling lower mortality novel objective patients hospitalized pharmacological treatment platform Potential Preparing public health Remdesivir Research resources Result resulting SARS SARS-CoV-2 Scientific community similarity statin statins Therapeutic treatment Treatment Vaccine with COVID-19
[DOI] 10.2196/21648 PMC 바로가기 [Article Type] Original Paper

Highlights in the fight against COVID-19: does autophagy play a role in SARS-CoV-2 infection?

Editorial

Published on 2020-11-052023-06-16
Journal: Autophagy [Category] MERS, SARS,

[키워드] ACE2 Chloroquine Dexamethasone Hydroxychloroquine LC3 Macroautophagy Remdesivir TMPRSS2
[DOI] 10.1080/15548627.2020.1844940 PMC 바로가기 [Article Type] Editorial

Tocilizumab in the treatment of rapidly evolving COVID-19 pneumonia and multifaceted critical illness: A retrospective case series

Case Series

Published on 2020-11-052022-10-04
Journal: Annals of Medicine and Surgery [Category] 치료법,

[키워드] Acute respiratory failure Administered administration Admission adverse effect analyzed Antibiotics antibody anticoagulation antivirals ARF Bacterial infection case sery characterized chronic Comorbidity COVID-19 COVID-19 patients COVID-19 pneumonia Critical Critically ill critically ill patients develop Dexamethasone dosage examined had more hallmark hospital hyperinflammation ICU infections intensive care interleukin-6 receptor intravenous intravenous infusion male measure mechanical ventilation mechanically ventilated mechanically ventilated patient monoclonal Mortality nine nosocomial not affect not significant outcome overall mortality oxygen support Oxygen therapy Patient Physiology Pneumonia Prevalence Prophylactic receiving Respiratory failure retrospective Safe survival rate therapy Tocilizumab tocilizumab therapy Treatment ventilated patient were recorded
[DOI] 10.1016/j.amsu.2020.10.061 PMC 바로가기 [Article Type] Case Series

SARS-CoV-2 pharmacologic therapies and their safety/effectiveness according to level of evidence

SARS-CoV-2 약리학적 치료법 및 근거 수준에 따른 안전성/유효성

Review

Published on 2020-11-012022-08-31
Journal: The American journal of emergency medicine [Category] meta-analysis, 임상, 치료제,

[키워드] Antiviral article Chloroquine Cochrane Library COVID-19 COVID-19 clinical outcomes COVID-19 pharmacologic treatments COVID-19 transmission criteria Dexamethasone drug Drug effectiveness Drug safety effective Effectiveness English evaluate Evidence HCQ Hydroxychloroquine include interferon interferon beta Interferon beta-1b JAMA level 1 Lopinavir Lopinavir-ritonavir Meta-analysis Mild mild to moderate mild to moderate disease moderate disease Mortality network peer-reviewed peer-reviewed study pharmacologic treatment pharmacologic treatments plasma plasma therapy PNAS Prognosis RCT RCTs reduced regimen Remdesivir respiratory Respiratory Support Result ribavirin Ritonavir SARS-CoV-2 searched severe disease significantly study inclusion systematic review Therapies therapy Vaccine
[DOI] 10.1016/j.ajem.2020.08.091 PMC 바로가기 [Article Type] Review

Kidney transplant patients with SARS-CoV-2 infection: The Brescia Renal COVID task force experience

SARS-CoV-2 감염 신장 이식 환자: Brescia Renal COVID 태스크포스 경험

Multicenter Study

Published on 2020-11-012022-09-11
Journal: American journal of transplantation : official jou [Category] SARS, 치료제,

[키워드] Acute kidney injury acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus addition Admission age antiviral drugs ARDS average Azithromycin baseline Brescia C-reactive protein Clinical characteristics clinical research/practice Cohort coronavirus coronavirus disease Coronavirus disease 2019 COVID COVID-19 D-dimer death Dexamethasone died disease Dyspnea higher risk Hydroxychloroquine Immunosuppression increased risk Infection infection and infectious agents - viral infectious infectious agent infectious agents Infectious disease kidney Kidney disease kidney disease: infectious. kidney transplant lack lymphopenia Methylprednisolone Mild Mild disease Older outcome Outpatient outpatients Patient patients patients with SARS-CoV-2 reduction renal required respiratory respiratory distress Respiratory distress syndrome risk risk factor Risk factors risk of death SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe symptoms syndrome tacrolimus the patient thrombocytopenia Tocilizumab Withdrawal
[DOI] 10.1111/ajt.16176 PMC 바로가기 [Article Type] Multicenter Study

[In patients hospitalized for COVID-19, does dexamethasone reduce 28-days mortality compared to standard treatment?]

[COVID-19로 입원한 환자에서 덱사메타손은 표준 치료에 비해 28일 사망률을 줄인다?]

Article

Published on 2020-11-012022-09-11
Journal: La Revue de médecine interne [Category] 임상,

[키워드] COVID-19 Dexamethasone Mortality patients hospitalized reduce
[DOI] 10.1016/j.revmed.2020.08.005 PMC 바로가기 [Article Type] Article