Unisexual Reproduction Drives Meiotic Recombination and Phenotypic and Karyotypic Plasticity in Cryptococcus neoformans단성 생식은 Cryptococcus neoformans에서 감수성 재조합과 표현형 및 핵형 가소성을 유도합니다Research Article Published on 2014-12-112022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] allele alleles analyzed Aneuploidy asexual asexual reproduction bisexual reproduction C. neoforman C. neoformans Candida albican Candida albicans characterized chromosomal chromosomal region chromosome chromosome 4 chromosomes collected comparison Cryptococcus Cryptococcus neoforman Cryptococcus neoformans diploid meiotic progeny drive duplication Evidence Evolution examined Frequency fungal fungal pathogen fungi heterozygosity implication initiated loss of heterozygosity MAT locus mating type mating types meiosis meiotic meiotic progeny meiotic recombination mitotic mitotic recombination mixing genetic material occur occurred Pathogenesis Pathogens phenotype phenotypic produced producing progeny quantification Quantitative Recombination recombination frequencies reflected Region regions reported reproduction sexual development sexual reproduction similarity spore spores thought undergo while [DOI] 10.1371/journal.pgen.1004849 PMC 바로가기 [Article Type] Research Article
Rapid testing and quantification of Salmonella in ileocaecal lymph nodes of Austrian pigs slaughtered for consumption오스트리아에서 소비를 위해 도축된 돼지의 맹장 림프절에서 살모넬라의 신속한 검사 및 정량화journal-article Published on 2014-10-012024-07-30 Journal: Research in Veterinary Science [Category] 살모넬라증, [키워드] Matrix-Lysis pig QMRA quantification Salmonella [DOI] 10.1016/j.rvsc.2014.06.016 [Article Type] journal-article
Integrative “Omics”-Approach Discovers Dynamic and Regulatory Features of Bacterial Stress Responses통합 "Omics" 접근 방식으로 세균 스트레스 반응의 동적 및 조절 기능 발견Research Article Published on 2013-06-202022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] (transcriptome adaptation adaptive mechanism adaptive mechanisms addition alternative approach assigned Author Bacteria cellular stress responses change choice complex conditions determine different dynamic Effect elevated temperature event events example exhibited expression expression level expression pattern expressome Factor Factors feature found fraction Frequency Gene Genes Genome help in addition to include initiated integration maintain mass spectrometry Microarrays mRNA mRNA level mRNA levels mRNAs Occurrence open reading frames operon organism oxygen phototrophic polar polysome Population post-transcriptional level Protein Proteins proteome provided quantification quorum regulated Regulation Regulatory reported required response RNA-Seq RpoE singlet oxygen Stress stress condition stress conditions stress response stress responses survival transcriptional activation transcriptional level transcriptional regulator transcriptional regulators Transcriptome translation translational was used [DOI] 10.1371/journal.pgen.1003576 PMC 바로가기 [Article Type] Research Article
A histological method for quantifying Plasmodium falciparum in the brain in fatal paediatric cerebral malaria치명적인 소아 뇌 말라리아에서 뇌의 플라스모디움 파르시파룸을 정량화하는 조직학적 방법Research Published on 2013-06-072024-08-13 Journal: Malaria Journal [Category] 말라리아, [키워드] Africa Autopsy cerebral malaria histology paediatric Plasmodium falciparum quantification [DOI] 10.1186/1475-2875-12-191 PMC 바로가기 [Article Type] Research
Comparative evaluation of a novel TaqMan real-time reverse transcription-polymerase chain reaction assay for hepatitis A virus detectionComparative Study Published on 2013-04-012023-05-31 Journal: The Journal of international medical research [Category] A형 간염, [키워드] hepatitis A virus quantification real-time reverse transcription–polymerase chain reaction sensitivity specificity [DOI] 10.1177/0300060513476434 [Article Type] Comparative Study
Approaching the Functional Annotation of Fungal Virulence Factors Using Cross-Species Genetic Interaction Profiling종간 유전적 상호작용 프로파일링을 사용하여 진균 독성 인자의 기능적 주석 접근Research Article Published on 2012-12-272022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accurate AIDS analyzed annotation approach Author C. neoforman C. neoformans C. neoformans gene C. neoformans genes calculation Cancer Cell cell surface Chemotherapy compared conserved correlated correlation correlations Cryptococcus neoforman Cryptococcus neoformans death deletion mutant deletion mutants demonstrated develop disease enhancement expressed expression Factor found function functional functional annotation fungal fungal pathogens fungi Gene gene deletion gene function Genetic genetic interaction genetic interactions Golgi Golgi apparatus growth HIV/AIDS HIV/AIDS patients human pathogen identify immunostimulatory individuals Infection inhibiting Interaction interactions lack mannose molecular mutant Organ transplant organism Organisms ortholog pathogen pathogenicity pathogenicity protein Pathogens patients phagocytosis predict predicted profile profiles Profiling promote quantification Quantitative recipient required S. cerevisiae Saccharomyces cerevisiae sequence supported suppression susceptible tested the cell understanding utility validation virulence virulence gene yeast [DOI] 10.1371/journal.pgen.1003168 PMC 바로가기 [Article Type] Research Article
Quantitative RT-PCR Detection of Hepatitis A Virus, Rotaviruses and Enteroviruses in the Buffalo River and Source Water Dams in the Eastern Cape Province of South AfricaArticle Published on 2012-11-052023-08-30 Journal: International Journal of Environmental Research an [Category] E형 간염, [키워드] detection enteric RNA viruses Enteroviruses hepatitis A virus quantification real-time RT-PCR rotaviruses Surface waters [DOI] 10.3390/ijerph9114017 PMC 바로가기 [Article Type] Article
Phased Whole-Genome Genetic Risk in a Family Quartet Using a Major Allele Reference Sequence주요 대립 유전자 참조 서열을 사용한 가족 4중주에서의 단계적 전체 게놈 유전적 위험Research Article Published on 2011-09-152022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Accuracy allele Analysis approach Author base pairs base pairs) Blood blood clot characterization coding compound heterozygosity contribute contributing to demonstrated develop disease disease risk disease-associated estimation facilitate family Gene genetic determinant genetic determinants genetic information genetic profile genetic risk genetic risk factor genetic risk factors Genetic variation Genome genomes Genotype Haplotype Human human leukocyte antigen identify Interpretation leukocyte loci lowest lung Major median medications methodology nuclear nuclear family occur pharmacological predisposition Pulmonary embolism quantification Quartet Recombination reference reference sequence risk Risk assessment risk for disease sequence Sequencing sequencing error sequencing errors therapy Thrombophilia variant whole-genome sequencing [DOI] 10.1371/journal.pgen.1002280 PMC 바로가기 [Article Type] Research Article
Immunohistochemistry as an Important Tool in Biomarkers Detection and Clinical Practice바이오마커 검출 및 임상 실습에서 중요한 도구로서의 면역조직화학Review Published on 2010-02-092022-08-08 Journal: Biomarker Insights [Category] Biochemistry, [키워드] Amino acid amino acids Analysis benefit Cell cell or tissue antigens clinical clinician collaboration complementary detection diagnostic differential diagnose differential diagnoses eosin expression Future hematoxylin Hematoxylin and eosin immunocytochemistry immunohistochemistry immunohistochemistry technique increase in infectious agent infectious agents Interpretation involved knowledge limitations methodology pathologist pathology Patient pooling Practice preparation problem problems prognostic Protein quantification reaction related Research review specific cellular populations Stage stages surgeon technique tissue antigen PMC 바로가기 [Article Type] Review
Plaque assay for human coronavirus NL63 using human colon carcinoma cellsMethodology Published on 2008-11-122022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] African green monkey Antiviral Avicel carboxymethyl-cellulose Cell Cell culture colds Colon coronavirus cytopathogenic effect days post infection demonstrated different disease Drug screening Effects HCoV HCoV-NL63 Human human pathogen humans Infection kidney log NL63 plaque Plaque assay plaque assays produced purification quantification replicated Result Support susceptibility tested utility viral infectivity virus virus infectivity virus replication virus stock [DOI] 10.1186/1743-422X-5-138 PMC 바로가기 [Article Type] Methodology