The associations of previous influenza/upper respiratory infection with COVID-19 susceptibility/morbidity/mortality: a nationwide cohort study in South KoreaArticle Published on 2021-11-032022-10-04 Journal: Scientific Reports [Category] MERS, 바이오마커, [키워드] adjusted odds ratio analyzed association cohort study Corporation COVID-19 COVID-19 cohort COVID-19 pandemic COVID-19 patient COVID-19 susceptibility database death defined Diseases extracorporeal membrane oxygenation Influenza influenza infection insurance intensive care invasive ventilation Logistic regression Medical research morbidity Mortality Non-COVID-19 Participants respiratory infection Risk factors Signs and symptoms South Korea susceptibility treatment history was collected was related with COVID-19 [DOI] 10.1038/s41598-021-00428-x PMC 바로가기 [Article Type] Article
Acceptance of seasonal influenza vaccination and associated factors among pregnant women in the context of COVID-19 pandemic in China: a multi-center cross-sectional study based on health belief modelResearch Published on 2021-11-032022-10-28 Journal: BMC Pregnancy and Childbirth [Category] COVID-19, MERS, SARS, [키워드] acceptance alleviate applied Associated factors benefit Characteristics China Co-infection collected conducted coronavirus disease COVID-19 COVID-19 pandemic cross-sectional enrolled evaluate Evidence expand Factor Health Health status Healthcare system help identify IMPROVE Influenza influenza infection influenza vaccination knowledge logistic regression model participant patients pregnant pregnant women reduce regression analysis Result risk risk of infection scatterplot seasonal Seasonal influenza Side effect supplementary material susceptibility vaccination Vaccine Vaccine hesitancy was used [DOI] 10.1186/s12884-021-04224-3 PMC 바로가기 [Article Type] Research
Association of ABO and Rh Blood Group in Susceptibility, Severity, and Mortality of Coronavirus Disease 2019: A Hospital-Based Study From Delhi, IndiaCellular and Infection Microbiology Published on 2021-11-022022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS, [키워드] ABO abo and rh blood groups analyzed association Bacterial Blood Blood Group chi-square test conducted coronavirus disease coronavirus disease (COVID-19) outbreak COVID-19 COVID-19 infection determine disease enrolled Frequency group groups India Infection investigated lower risk Mann–Whitney test Mortality non-infectious Odds ratio Patient patients positive Real-time PCR recruited Result Retrospective study Rh+ risk of COVID-19 severity Severity of disease shown significantly single-center susceptibility susceptible Viral diseases with COVID-19 [DOI] 10.3389/fcimb.2021.767771 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Potential benefit of vitamin D supplementation in people with respiratory illnesses, during the COVID‐19 pandemicMini‐review Published on 2021-11-022022-11-01 Journal: Clinical and translational science [Category] COVID-19, MERS, [키워드] active form acute respiratory distress addition ARDS association benefit clinical Consequences Control coronavirus disease COVID‐19 COVID‐19 infection cytokine Cytokine storm Cytokines decrease deficiency Evidence Hospitalized immunomodulatory effects incidence increase in indicate Infection infections Lower respiratory tract mitigate Mortality offer outcome pandemic Patient Population Potential reduce reported Respiratory disease respiratory diseases respiratory illnesses risk serious complication severity susceptibility susceptible syndrome Tuberculosis vitamin D deficiency vitamin D level Vitamin D supplementation [DOI] 10.1111/cts.13044 PMC 바로가기 [Article Type] Mini‐review
Hypoxia alters the expression of ACE2 and TMPRSS2 SARS-CoV-2 cell entry mediators in hCMEC/D3 brain endothelial cells저산소증은 hCMEC/D3 뇌 내피 세포에서 ACE2 및 TMPRSS2 SARS-CoV-2 세포 진입 매개체의 발현을 변경합니다Article Published on 2021-11-012022-09-11 Journal: Microvascular research [Category] SARS, 유전자 메커니즘, [키워드] accompanied ACE2 ACE2 mRNA acute respiratory syndrome coronavirus Alter angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Angiotensin-converting enzyme 2 (ACE2) blood-brain barrier Blood-brain barrier (BBB) Blot Brain Cell cell entry changes in Control control group coronavirus 2 COVID19 decrease Effect endothelial Endothelial cell endothelial cell damage endothelial cells enzyme expression expression of SARS-CoV-2 Factor followed by groups Human Human brain Human cerebral microvascular endothelial cells (hCMEC/D3) hypoxia hypoxic hypoxic condition identify IL-6 in vitro induce interleukin interleukin 6 marker mechanism mRNA Neurological complication Neurological complications oxygen pro-inflammatory cytokine protease Protein protein expression qPCR receptor reduced regulate replicated respiratory SARS-CoV-2 SARS-CoV-2 cell SARS-COV-2 infection Serine serine 2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 subsequent susceptibility TMPRSS2 TMPRSS2 expression TMPRSS2 protein transmembrane transmembrane protease serine 2 transmembrane protease serine 2 (TMPRSS2) von Willebrand factor western blot [DOI] 10.1016/j.mvr.2021.104232 PMC 바로가기 [Article Type] Article
Relevance between COVID-19 and host genetics of immune responseReview article Published on 2021-11-012022-10-05 Journal: Saudi Journal of Biological Sciences [Category] 유전자 메커니즘, [키워드] 2019-nCoV ACE2 ACEAngiotensin Converting Enzyme Activation acute respiratory syndrome Affect allele frequency Alter alveolar angiotensin angiotensin converting enzyme Antigen presentation antigenic antigenic peptide association binding caused CD4+ CD8+ cellular immunity change changes in China complications coronavirus disease COVID-19 cytokine secretion death disease Endoplasmic reticulum expressed expression expression data expression level Gas exchange gene product Genes Genetic Genotype HBVHepatitis B virus HCVHepatitis C virus Hepatitis B virus hepatitis C virus high mortality highlight HIVhuman immunodeficiency virus HLA HLA class I HLA gene HLAHuman leukocyte antigen host genetics Human immunodeficiency virus human leukocyte antigen immune immune response impair Infection Lungs MHC class I Non-small cell lung carcinoma NSCLCNon-small cell lung carcinoma outbreak pathogen Pathogenesis peptide phenotype pneumocyte Pneumocytes polymorphism populations precursor present antigen progression RASRenin-angiotensin system Relevance renin-angiotensin system reported responsible resulting SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARSSevere Acute Respiratory Syndrome Severe acute respiratory syndrome severe hypoxia Single nucleotide polymorphism SNPSingle nucleotide polymorphism Spread susceptibility T lymphocytes T-cell responses T-cells variant Variation viral entry viral infection virus virus spike protein viruses Wuhan [DOI] 10.1016/j.sjbs.2021.07.037 [Article Type] Review article
Cyclic 68 Ga-Labeled Peptides for Specific Detection of Human Angiotensin-Converting Enzyme 2Basic Science Investigation Published on 2021-11-012022-10-30 Journal: Journal of Nuclear Medicine [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome affected angiotensin-converting enzyme 2 ARDS binding biodistribution calculated Cohort compounds Concentration coronavirus coronavirus disease COVID-19 COVID-19 patients cyclic detect detection generate glycol hACE2 half-maximal inhibitory concentration Human humanized hypothese identify identity inhibitor linear linker liver lung Lungs modulation murine murine model organ organ injury organ-specific peptide pet Pharmacologic reduction residues SARS-CoV-2 SARS-COV-2 infection small intestine Specific susceptibility transgenic transgenic model Visual was determined was used [DOI] 10.2967/jnumed.120.261768 PMC 바로가기 [Article Type] Basic Science Investigation
Does immune recognition of SARS-CoV2 epitopes vary between different ethnic groups?SARS-CoV2 에피토프의 면역 인식은 인종 그룹마다 다릅니다.Article Published on 2021-11-012022-09-11 Journal: Virus research [Category] SARS, 유전자 메커니즘, [키워드] Affect affecting Alter distribution Effect Efficacy effort elicit epitope Epitope-based vaccine Epitopes Ethnic groups Ethnic variations European Europeans expected Factor HLA HLA allele HLA alleles HLA system Human human leukocyte antigen humans identify immune immune response immunogenic Immunological response impacted less leukocyte manifestation mechanism MHC MHC alleles Mutation pandemic peptide peptides Population populations probe question Recognition recognize Research response Result SARS-CoV2 SARS-CoV2 infection South Asian susceptibility T-cell T-cell Response turn unlikely viral genomes viral infection virus while [DOI] 10.1016/j.virusres.2021.198579 PMC 바로가기 [Article Type] Article
Association of rs11549465 (C1772T) variant of hypoxia-inducible factor-1α with Covid-19 susceptibility. A population-based epidemiological study저산소증 유발 인자-1α의 rs11549465(C1772T) 변이체와 Covid-19 감수성의 연관성. 인구 기반 역학 연구Article Published on 2021-11-012022-09-11 Journal: Human Cell [Category] 변종, [키워드] Epidemiological study susceptibility variant [DOI] 10.1007/s13577-021-00601-4 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Variants of Concern우려의 SARS-CoV-2 변종Review Published on 2021-11-012022-09-11 Journal: Yonsei medical journal [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Adenovirus adenovirus vector vaccines Alpha Alpha variant Beta concern coronavirus COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines current delta variant Delta variants disease severity effective Effectiveness effort Epidemiology evade immune responses individuals less measure molecular features MONITOR monoclonal antibody Monoclonal antibody treatments mRNA preventing infection reduce SARS-CoV-2 SARS-CoV-2 lineage severe acute respiratory syndrome Coronavirus severe disease susceptibility susceptible Transmissibility Transmission Vaccine variant variant of concern variants virus VoC VOCs [DOI] 10.3349/ymj.2021.62.11.961 PMC 바로가기 [Article Type] Review