Structure-Based Identification and Functional Characterization of a Lipocalin in the Malaria Parasite Plasmodium falciparumArticle Published on 2020-06-232024-08-28 Journal: Cell Reports [Category] 말라리아, [키워드] blood stage Food vacuole lipocalin malaria oxidative stress parasitophorous vacuole.
Air Pollution and COVID-19: The Role of Particulate Matter in the Spread and Increase of COVID-19’s Morbidity and MortalityReview Published on 2020-06-222022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] ACE2 angiotensin-converting enzyme 2 atmospheric average Cell close contact Concentration coronavirus COVID-19 COVID-19 patient greater highlight increase induce Inflammation inflammatory storm involved Italian lung cell matter New coronavirus oxidative stress pandemic Particulate Particulate matter Pollution positive correlation receptor responsible role severity shown Spread spread of COVID-19 susceptibility sustained Symptoms the epidemic Transmission virus virus spread World Health Organization [DOI] 10.3390/ijerph17124487 PMC 바로가기 [Article Type] Review
Adding Colchicine to the Antiretroviral Medication – Lopinavir/Ritonavir (Kaletra) in Hospitalized Patients with Non-Severe Covid-19 Pneumonia: A Structured Summary of a Study Protocol for a Randomized Controlled TrialLetter Published on 2020-06-052022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] 1:1 added Adding anti-inflammatory effect Antibiotics anticipated antioxidant antioxidants antiretroviral blinded both group CDC center change Clinical course Clinical improvement Colchicine component Consensus Controlled COVID-19 COVID-19 infection COVID-19 patients digoxin dissemination dosage double blind double-blind study element enrolled equation estimate Final GFR glomerular filtration rate group help Hospital stay hospitalized COVID-19 patients hypersensitivity hypoxic in both group infected with COVID-19 Inflammation inflammatory disorders Inpatient interleukin-8 intubation invasive Iran Kaletra kidney transplant recipients Lopinavir/ritonavir lung Lung CT MDA mechanism Minerals Nasopharyngeal swab National number objective outcome oxidative stress Oxygenation pandemic parallel group participant pathologic pathway Patient patients percentage Pneumonia positive Prospective protocol QTc randomised randomised controlled trial randomization Randomized Rate Ratio receive recruited recruitment reducing reduction Registered RT -PCR Sample size serum creatinine status Tehran time tomography Trace element treat treated Treatment two group two groups Vitamin website WHO guideline with COVID-19 [DOI] 10.1186/s13063-020-04455-3 PMC 바로가기 [Article Type] Letter
The Mechanistic Target of Rapamycin (mTOR): Novel Considerations as an Antiviral TreatmentArticle Published on 2020-06-012023-06-14 Journal: Current Neurovascular Research [Category] MERS, SARS, [키워드] AKT AMP activated protein kinase (AMPK) angiotensin converting enzyme 2 Apoptosis autophagy Coronaviruses COVID-19 Cytokines Diabetes Mellitus Inflammation Influenza interferons Interleukins macrophage inflammatory protein 1-α (MIP-1α) mechanistic target of rapamycin (mTOR) metformin monocyte chemoattractant protein 1 (MCP-1) mTOR Complex 1 (mTORC1) mTOR Complex 2 (mTORC2) oxidative stress SARS-CoV-2 tumor necrosis factor-α virion [DOI] 10.2174/1567202617666200425205122 PMC 바로가기 [Article Type] Article
N-Acetylcysteine: A potential therapeutic agent for SARS-CoV-2Article Published on 2020-05-302023-06-15 Journal: Medical Hypotheses [Category] MERS, SARS, [키워드] coronavirus COVID-19 glutathione N-acetylcysteine NAC NLRP3 oxidative stress redox potential redox status SARS-CoV-2 T cell exhaustion TNF-ɑ [DOI] 10.1016/j.mehy.2020.109862 PMC 바로가기 [Article Type] Article
Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 CrisisReview Published on 2020-05-272022-10-31 Journal: Nutrients [Category] COVID-19, MERS, SARS, [키워드] ACE2 adequate diet Anti-inflammatory Anti-inflammatory effects antibody production antioxidant antioxidant effects carotenoid cell entry receptor challenge concerning coronavirus COVID-19 COVID-19 crisis crisis Cytokines diet dietary Dietary fiber enzyme example fatty acids Frequently General population global pandemic gut microbiota highlight immune response immune system include Infection infection risk Inflammation innate immune system macronutrients NF-kB nuclear factors nutrient oxidative stress Protein protein intake reactive oxygen species reduce shown Support System trace elements transcription factor transcription factors turn viral cellular infection vitamin A Vitamin C Vitamin D World Health Organization [DOI] 10.3390/nu12061562 PMC 바로가기 [Article Type] Review
Are Iranian Sulfur Mustard Gas-Exposed Survivors More Vulnerable to SARS-CoV-2? Some Similarity in Their PathogenesisResponder Tools Published on 2020-05-182022-10-31 Journal: Disaster Medicine and Public Health Preparedness [Category] COVID-19, MERS, SARS, [키워드] ACE2 acute respiratory syndrome Angiotensin-converting enzyme caused coronavirus Coronavirus disease 2019 COVID-19 COVID-19 infection Cytokine storm dysregulation entry receptor functional Health immune system Infectious disease Iran lung Lung injury mustard mustard gas overexpression oxidative stress pathogenesis of SARS-CoV-2 pathologic Pulmonary infection receptor SARS-CoV-2 similarity suggested sulfur survivor susceptibility susceptible veteran [DOI] 10.1017/dmp.2020.156 PMC 바로가기 [Article Type] Responder Tools
Cardiac Manifestations of Coronavirus Disease 2019 (COVID-19): A Comprehensive ReviewCardiology Published on 2020-05-082022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Acute cardiac injury acute myocardial injury acute respiratory syndrome cardiac cardiac injury cardiac manifestations China clinical feature Comprehensive consequence coronavirus coronavirus disease coronavirus disease (COVID-19) COVID-19 COVID-19 pandemic emerging disease Features Heart injury highlight individual Infection Inflammatory inflammatory storm Injury kidney Laboratory liver management manifestation mechanism myocardial injury organ-specific oxidative stress pandemic Prognosis reported respiratory findings review SARS-CoV-2 spread to troponins viral invasion [DOI] 10.7759/cureus.8021 PMC 바로가기 [Article Type] Cardiology
Potential Cytoprotective Activity of Ozone Therapy in SARS-CoV-2/COVID-19Review Published on 2020-05-062022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] activity acute respiratory syndrome affected antioxidant articles caused China Clinical management Clinical studies clinically Complication Controlled clinical trial coronavirus COVID-19 disease Effect effective experimental model expression homeostasis IL-1β IL-6 Inflammation Inflammatory diseases Keap1/Nrf2/ARE pathway management mechanism of action modulation molecular mechanism NF-κB Nrf2 organ organ damage outbreak oxidative stress ozone therapy 1 pathway peer-reviewed physiological Potential Research SARS-CoV-2 shown Support systemic therapy tissue damage viral infection viral infections [DOI] 10.3390/antiox9050389 PMC 바로가기 [Article Type] Review
Oxidative Stress as Key Player in Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) InfectionArticle Published on 2020-04-302023-07-01 Journal: Archives of medical research [Category] SARS, [키워드] COVID-19 oxidative stress SARS-CoV virus infection [DOI] 10.1016/j.arcmed.2020.04.019 PMC 바로가기 [Article Type] Article