Are saliva and deep throat sputum as reliable as common respiratory specimens for SARS-CoV-2 detection? A systematic review and meta-analysis타액과 인후 가래는 SARS-CoV-2 검출을 위한 일반적인 호흡기 표본만큼 신뢰할 수 있습니까? 체계적인 검토 및 메타 분석Review Published on 2021-09-012022-09-11 Journal: American journal of infection control [Category] SARS, 치료기술, [키워드] 95% CI 95% confidence interval Analysis Asymptomatic Asymptomatic cases asymptomatic patients Bronchoalveolar lavage fluid COVID-19 COVID-19 infection COVID-19 pandemic definitive diagnosis diagnostic diagnostic sensitivity diagnostic test diagnostic value disease severity DTS Evidence inclusion criteria Infection Laboratory Meta-analysis Mild nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs oropharyngeal swab oropharyngeal swabs patients with COVID-19 performed provide Quantitative analysis raise random-effects model reliability respiratory specimen retrieved RT-PCR RT-PCR diagnostic test RT-PCR tests Saliva sampling SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection sensitivity Severe patient severe patients severity specimen specimens sputum Stata Stata software Support swabs symptomatic patient Symptomatic patients systematic review Systemic review the disease Viral load was performed [DOI] 10.1016/j.ajic.2021.03.008 PMC 바로가기 [Article Type] Review
Initial Evaluation of a Mobile SARS-CoV-2 RT-LAMP Testing Strategy모바일 SARS-CoV-2 RT-LAMP 테스트 전략의 초기 평가Article Published on 2021-09-012022-09-12 Journal: Journal of biomolecular techniques : JBT [Category] SARS, 진단, [키워드] acute respiratory syndrome asymptomatic individual collected colorimetric LAMP Concordance coronavirus criteria Donor evaluated false-negative rate group heat-inactivated identify individual isothermal amplification Laboratory limitations Mobile molecular Molecular biology point-of-care point-of-care test polymerase chain positive qRT-PCR qRT-PCR assay qRT-PCR assays Quantitative RT-LAMP Saliva saliva-based. SARS-CoV-2 SARS-CoV-2 RNA Strategy subsequent Surveillance tested Testing the United State Volunteer [DOI] 10.7171/jbt.21-32-03-009 PMC 바로가기 [Article Type] Article
Real-time optical analysis of a colorimetric LAMP assay for SARS-CoV-2 in saliva with a handheld instrument improves accuracy compared with endpoint assessment휴대용 기기를 사용하여 타액에서 SARS-CoV-2에 대한 비색 LAMP 분석의 실시간 광학 분석으로 종말점 평가와 비교하여 정확도 향상Article Published on 2021-09-012022-09-11 Journal: Journal of biomolecular techniques : JBT [Category] SARS, 진단, 치료기술, [키워드] Accuracy acute respiratory syndrome coronavirus Analysis approach approved bypassed change clinical sample clinical samples collected color controlling coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 Course COVID-19 current detect detection system diagnostic diagnostic testing diagnostics drop drug Drug administration Endpoint FDA approval food hydrolysis IMPROVE inactivated invasive isothermal LAMP less limit of detection MONITOR Nasopharyngeal swab nasopharyngeal swabs near patient. negative sample nucleic acid nucleic acid amplification nucleotide observation optical pandemic Patient pH indicator positive processed protocol Quantitative reaction respiratory RNA RNA detection RNA extraction RT-LAMP Saliva SARS-CoV-2 SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specimen this system Viral Viral load virus widespread [DOI] 10.7171/jbt.21-3203-011 PMC 바로가기 [Article Type] Article
MiR-200c-3p expression may be associated with worsening of the clinical course of patients with COVID-19Original Article Published on 2021-09-012022-10-30 Journal: Molecular Biology Research Communications [Category] COVID-19, [키워드] affected Biomarkers Clinical course condition COVID-19 expression expression level Factor greater group groups host cell independent Infection mechanism microRNA Oxygen therapy Patient patients with COVID-19 positive public health emergency qPCR regression analysis respiratory disorder Risk factors Saliva SARS-CoV-2 severity Symptomatic patients systemic arterial hypertension worsening [DOI] 10.22099/mbrc.2021.40555.1631 PMC 바로가기 [Article Type] Original Article
Sensitive detection of anti-spike antibodies enables improved understanding of SARS-CoV-2 pathogenesis스파이크 방지 항체의 민감한 검출을 통해 SARS-CoV-2 병인에 대한 이해 향상Editorial Published on 2021-09-012022-09-11 Journal: Immunology [Category] SARS, 진단, 치료기술, [키워드] active infections anti-spike antibody Anti-viral immune response anti-viral immune responses antibody complement detect ELISA help immune response immune responses immunological protection Infection infections isotype likelihood mass mass vaccination natural infection pandemic positive result predict provide re-infected Saliva SARS-CoV-2 SARS-CoV-2 pathogenesis SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody sensitive serum specific antibodies spike glycoprotein Test tide turn vaccination Vaccinations Viral viral infection viral infections Viral RNA virus [DOI] 10.1111/imm.13399 PMC 바로가기 [Article Type] Editorial
Intra-host non-synonymous diversity at a neutralizing antibody epitope of SARS-CoV-2 spike protein N-terminal domainSARS-CoV-2 스파이크 단백질 N-말단 도메인의 중화 항체 에피토프에서 숙주 내 비 동의어 다양성Article Published on 2021-09-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] SARS, 변종, 진단, [키워드] Affect Amino acid amino acid residue binding Clusters collected Course COVID-19 COVID-19 patient COVID-19 patients database deep sequencing demonstrated determine epitope Epitopes Frequency Genetic hotspot Illumina Illumina sequencing Infection Intra-host diversity monoclonal antibodies Mutation mutations N-terminal domain Nanopore nanopore sequencing Neutralizing neutralizing antibody neutralizing epitope neutralizing epitopes Non-synonymous Non-synonymous mutation nucleotide Patient performed respiratory respiratory specimen respiratory tract Saliva Sanger sequencing SARS-CoV-2 SARS-CoV-2 spike protein sequence sequenced sequences Sequencing severe disease single nucleotide polymorphisms specimen spike spike gene Spike protein sputum the spike protein therapeutic efficacy Viral viral genome was performed [DOI] 10.1016/j.cmi.2020.10.030 PMC 바로가기 [Article Type] Article
Performance of saliva as a specimen to detect SARS-CoV-2SARS-CoV-2 검출을 위한 검체로서의 타액의 성능Article Published on 2021-09-012022-09-11 Journal: Journal of Clinical Virology [Category] SARS, 치료기술, [키워드] affected alternative average COVID-19 Ct-value Ct-values detect Detection sensitivity Epidemic False negative False negative rate false negatives functions Health increase in massive Nasopharyngeal swab nasopharyngeal swabs NPs ORF1 ORF1ab Patient performance positive RNA RNA extraction RT-PCR Saliva saliva samples SARS-CoV-2 sensitivities sensitivity specimen Standard deviation the patient Variability viral gene viral genes [DOI] 10.1016/j.jcv.2021.104913 PMC 바로가기 [Article Type] Article
Saliva “Treat-and-Heat” Triplex Reverse Transcription Loop-Mediated Isothermal Amplification Assay for SARS-CoV-2SARS-CoV-2에 대한 타액 "치료 및 가열" 삼중 역전사 루프 매개 등온 증폭 분석Article Published on 2021-09-012022-09-11 Journal: Journal of biomolecular techniques : JBT [Category] SARS, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Amplicon amplification Analysis clinically coronavirus cross-contamination detect diagnostic diagnostic testing diagnostics EDTA expected extraction extraction-free False positive faster Filipinos Fluorescence fraction identify infectious Infrastructure isothermal amplification Laboratory laboratory procedures Loop-mediated isothermal amplification majority melt curve. molecular molecular diagnostics nasopharyngeal Patient patients Phosphine predicted primer Primers proteinase Proteinase K protocol protocols provided qPCR test quantitative PCR respiratory reverse transcription RNA robustness RT-qPCR RT-qPCR test Saliva salivary SARS-CoV-2 severe acute respiratory syndrome Coronavirus triplex uracil Viral Viral load viral loads virus [DOI] 10.7171/jbt.21-3203-014 PMC 바로가기 [Article Type] Article
RT-PCR/MALDI-TOF mass spectrometry-based detection of SARS-CoV-2 in saliva specimensArticle Published on 2021-09-012023-07-02 Journal: Journal of medical virology [Category] SARS, [키워드] MALDI-TOF real-time RT-PCR Saliva SARS-CoV-2 [DOI] 10.1002/jmv.27069 PMC 바로가기
HRPZyme Assisted Recognition of SARS-CoV-2 infection by Optical Measurement (HARIOM)광학 측정(HARIOM)을 통한 HRPZyme 지원 SARS-CoV-2 감염 인식Article Published on 2021-09-012022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antibody detection Antigen antigen tests assays colorimetric detection Concordance coronavirus COVID-19 detect diagnostics DNAZyme enzymatic assay genetic material Health Policies HRPZyme include Infection less mass Mass screening measurement molecular NAT NATs negative sample nucleic acid On-site diagnostics. PCR positive promise public health Recognition resource respiratory resulting robust Saliva SARS-CoV-2 SARS-COV-2 infection sensitivity Sensitivity and specificity severe acute respiratory syndrome Coronavirus specificity subjects to define Viral Viral protein Viral RNA while [DOI] 10.1016/j.bios.2021.113280 PMC 바로가기 [Article Type] Article