Sensitive detection of anti-spike antibodies enables improved understanding of SARS-CoV-2 pathogenesis스파이크 방지 항체의 민감한 검출을 통해 SARS-CoV-2 병인에 대한 이해 향상Editorial Published on 2021-09-012022-09-11 Journal: Immunology [Category] SARS, 진단, 치료기술, [키워드] active infections anti-spike antibody Anti-viral immune response anti-viral immune responses antibody complement detect ELISA help immune response immune responses immunological protection Infection infections isotype likelihood mass mass vaccination natural infection pandemic positive result predict provide re-infected Saliva SARS-CoV-2 SARS-CoV-2 pathogenesis SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody sensitive serum specific antibodies spike glycoprotein Test tide turn vaccination Vaccinations Viral viral infection viral infections Viral RNA virus [DOI] 10.1111/imm.13399 PMC 바로가기 [Article Type] Editorial
Intra-host non-synonymous diversity at a neutralizing antibody epitope of SARS-CoV-2 spike protein N-terminal domainSARS-CoV-2 스파이크 단백질 N-말단 도메인의 중화 항체 에피토프에서 숙주 내 비 동의어 다양성Article Published on 2021-09-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] SARS, 변종, 진단, [키워드] Affect Amino acid amino acid residue binding Clusters collected Course COVID-19 COVID-19 patient COVID-19 patients database deep sequencing demonstrated determine epitope Epitopes Frequency Genetic hotspot Illumina Illumina sequencing Infection Intra-host diversity monoclonal antibodies Mutation mutations N-terminal domain Nanopore nanopore sequencing Neutralizing neutralizing antibody neutralizing epitope neutralizing epitopes Non-synonymous Non-synonymous mutation nucleotide Patient performed respiratory respiratory specimen respiratory tract Saliva Sanger sequencing SARS-CoV-2 SARS-CoV-2 spike protein sequence sequenced sequences Sequencing severe disease single nucleotide polymorphisms specimen spike spike gene Spike protein sputum the spike protein therapeutic efficacy Viral viral genome was performed [DOI] 10.1016/j.cmi.2020.10.030 PMC 바로가기 [Article Type] Article
Performance of saliva as a specimen to detect SARS-CoV-2SARS-CoV-2 검출을 위한 검체로서의 타액의 성능Article Published on 2021-09-012022-09-11 Journal: Journal of Clinical Virology [Category] SARS, 치료기술, [키워드] affected alternative average COVID-19 Ct-value Ct-values detect Detection sensitivity Epidemic False negative False negative rate false negatives functions Health increase in massive Nasopharyngeal swab nasopharyngeal swabs NPs ORF1 ORF1ab Patient performance positive RNA RNA extraction RT-PCR Saliva saliva samples SARS-CoV-2 sensitivities sensitivity specimen Standard deviation the patient Variability viral gene viral genes [DOI] 10.1016/j.jcv.2021.104913 PMC 바로가기 [Article Type] Article
Saliva “Treat-and-Heat” Triplex Reverse Transcription Loop-Mediated Isothermal Amplification Assay for SARS-CoV-2SARS-CoV-2에 대한 타액 "치료 및 가열" 삼중 역전사 루프 매개 등온 증폭 분석Article Published on 2021-09-012022-09-11 Journal: Journal of biomolecular techniques : JBT [Category] SARS, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Amplicon amplification Analysis clinically coronavirus cross-contamination detect diagnostic diagnostic testing diagnostics EDTA expected extraction extraction-free False positive faster Filipinos Fluorescence fraction identify infectious Infrastructure isothermal amplification Laboratory laboratory procedures Loop-mediated isothermal amplification majority melt curve. molecular molecular diagnostics nasopharyngeal Patient patients Phosphine predicted primer Primers proteinase Proteinase K protocol protocols provided qPCR test quantitative PCR respiratory reverse transcription RNA robustness RT-qPCR RT-qPCR test Saliva salivary SARS-CoV-2 severe acute respiratory syndrome Coronavirus triplex uracil Viral Viral load viral loads virus [DOI] 10.7171/jbt.21-3203-014 PMC 바로가기 [Article Type] Article
RT-PCR/MALDI-TOF mass spectrometry-based detection of SARS-CoV-2 in saliva specimensArticle Published on 2021-09-012023-07-02 Journal: Journal of medical virology [Category] SARS, [키워드] MALDI-TOF real-time RT-PCR Saliva SARS-CoV-2 [DOI] 10.1002/jmv.27069 PMC 바로가기
HRPZyme Assisted Recognition of SARS-CoV-2 infection by Optical Measurement (HARIOM)광학 측정(HARIOM)을 통한 HRPZyme 지원 SARS-CoV-2 감염 인식Article Published on 2021-09-012022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antibody detection Antigen antigen tests assays colorimetric detection Concordance coronavirus COVID-19 detect diagnostics DNAZyme enzymatic assay genetic material Health Policies HRPZyme include Infection less mass Mass screening measurement molecular NAT NATs negative sample nucleic acid On-site diagnostics. PCR positive promise public health Recognition resource respiratory resulting robust Saliva SARS-CoV-2 SARS-COV-2 infection sensitivity Sensitivity and specificity severe acute respiratory syndrome Coronavirus specificity subjects to define Viral Viral protein Viral RNA while [DOI] 10.1016/j.bios.2021.113280 PMC 바로가기 [Article Type] Article
Development of a genotyping platform for SARS-CoV-2 variants using high-resolution melting analysis고해상도 용융 분석을 이용한 SARS-CoV-2 변이체 유전자형 플랫폼 개발Article Published on 2021-09-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] SARS, 변종, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus Affect Analysis characteristic clade coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 determinant development FIVE genome sequence genotyping Genotyping method GISAID high resolution High resolution melting High-resolution higher infectivity Human human saliva identify Infection investigated matrix effect mutant viruses mutated Mutation Novel coronavirus platform Real-time PCR reduce reported reverse transcription RNA fragment RNA virus Saliva SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strains SARS-CoV-2 transmission SARS-CoV-2 variant SARS-CoV-2 variants sequence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Support synthetic DNA fragment synthetic DNA fragments undergo virus mutation wild-type [DOI] 10.1016/j.jiac.2021.06.007 PMC 바로가기 [Article Type] Article
Logistic advantage of two-step screening strategy for SARS-CoV-2 at airport quarantine공항 검역에서 SARS-CoV-2에 대한 2단계 스크리닝 전략의 물류 이점Article Published on 2021-09-012022-09-11 Journal: Travel medicine and infectious disease [Category] SARS, 치료기술, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 airport all subjects Antigen Care Chain Reaction CLEIA Concentration concentrations Concordance coronavirus COVID-19 enzyme enzyme immunoassay False negative false negatives followed by high accuracy immunoassay initial initial screening International Japan labor-intensive less logistics NAAT nucleic acid nucleic acid amplification PCR Point polymerase chain polymerase chain reaction positive Prevent Quantitative quarantine reduce reduced required risk Saliva SARS-CoV-2 SARS-CoV-2 antigen screening strategy screening test severe acute respiratory syndrome Coronavirus significant increase significantly subjects tested time-consuming utilization virus [DOI] 10.1016/j.tmaid.2021.102127 PMC 바로가기 [Article Type] Article
Molecular Beacons Allow Specific RT-LAMP Detection of B.1.1.7 Variant SARS-CoV-2분자 비콘은 B.1.1.7 변종 SARS-CoV-2의 특정 RT-LAMP 검출을 허용합니다Article Published on 2021-09-012022-09-11 Journal: Journal of biomolecular techniques : JBT [Category] SARS, 변종, 치료기술, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha Alpha variant amplification B.1.1.7 characteristic concerning coronavirus coronavirus disease Coronavirus disease 2019 Course COVID-19 current detect detection diagnostic diagnostic test Fluorescence gene encoding Genetic variant genetic variants isothermal amplification molecular molecular diagnostic test. other variant other variants over pair pandemic positive primer sets quantitative PCR reverse transcription RT-LAMP Saliva SARS-CoV-2 signal Specific Spike protein Spread variant viral spike protein [DOI] 10.7171/jbt.21-3203-004 PMC 바로가기 [Article Type] Article
Rapid, Affordable, and Scalable SARS-CoV-2 Detection From Saliva타액에서 빠르고 저렴하며 확장 가능한 SARS-CoV-2 감지Article Published on 2021-09-012022-09-11 Journal: Journal of biomolecular techniques : JBT [Category] SARS, 치료기술, [키워드] 384-well format acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Combination coronavirus detection determine extraction extraction-free detection fluorescent fluorescent dye Fluorescent LAMP isothermal amplification lab LAMP less Loop-mediated isothermal amplification Patient pH indicator phenol Phenol red point-of-care provide Rapid reaction reagent real time reduce redundancy reporter robust RT-LAMP Saliva saliva detection. SARS-CoV-2 setup severe acute respiratory syndrome Coronavirus [DOI] 10.7171/jbt.21-3203-010 PMC 바로가기 [Article Type] Article