sera – Page 52 – Communicable Diseases Research

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization

Research

Published on 2021-07-082022-10-05
Journal: Nature [Category] 변종,

Developing Recombinant Antibodies by Phage Display Against Infectious Diseases and Toxins for Diagnostics and Therapy

진단 및 치료를 위한 감염성 질환 및 독소에 대한 파지 디스플레이에 의한 재조합 항체 개발

Review

Published on 2021-07-072022-09-12
Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 진단,

Stable trimer formation of spike protein from porcine epidemic diarrhea virus improves the efficiency of secretory production in silkworms and induces neutralizing antibodies in mice

Research Article

Published on 2021-07-072022-10-28
Journal: Veterinary Research [Category] Coronavirus,

[키워드] cause contributing to coronavirus demonstrated diarrhea economic loss Efficiency elicit epidemic diarrhea evaluated expression expression vector Genetic high mortality rate homotrimer host cell Humoral immunity IgG immunization IMPROVE induce Infection intrinsically less mice motif mouse Neonatal neutralizing antibody pathogen PEDV platform Porcine epidemic diarrhea virus PROTECT protective effect Protein provide S protein S proteins sera serum Silkworm-baculovirus expression vector system Spike protein STABLE strain Subunit vaccine supplementary material the S protein trimer trimeric trimeric motif Vaccine Vaccine development Vero Cell viral membrane virus watery
[DOI] 10.1186/s13567-021-00971-5 PMC 바로가기 [Article Type] Research Article

Characterization of a new SARS-CoV-2 variant that emerged in Brazil

브라질에서 출현한 새로운 SARS-CoV-2 변종 특성 규명

Comparative Study

Published on 2021-07-062022-09-10
Journal: Proceedings of the National Academy of Sciences of [Category] SARS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition animal model Antigen aspartic acid BNT162b2 Brazil characterization characterized circulating comparable convalescent human plasma convalescent patient Convalescent patients convalescent sera coronavirus COVID-19 deaths glycine hamster hamsters Host host range in viral Infection Japan less Lower respiratory tract Messenger RNA mice multiple mutation multiple mutations neutralization titer Neutralizing antibodies neutralizing antibody new SARS-CoV-2 number of deaths P.1 P.1 variant P.1 variants passive transfer pathogenicity Patient plasma position prevented protective immune response Protein reduced Reinfection Replication replicative respiratory S protein SARS-CoV-2 SARS-CoV-2 disease SARS-COV-2 infection SARS-CoV-2 strain sera serum severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 shown Significance strain Strains Syrian hamsters the S protein transfer Vaccine vaccinee variant variant of SARS-CoV-2 variants Viral viral infectivity virus replication
[DOI] 10.1073/pnas.2106535118 PMC 바로가기 [Article Type] Comparative Study

Immunogenicity and efficacy of one and two doses of Ad26.COV2.S COVID vaccine in adult and aged NHP

성인 및 노년 NHP에서 Ad26.COV2.S COVID 백신의 1회 및 2회 용량의 면역원성 및 효능

Article

Published on 2021-07-052022-09-11
Journal: The Journal of Experimental Medicine [Category] SARS, 변종, 진단,

[키워드] Ad26 Ad26.COV2.S Ad26.COV2.S vaccine B.1.1.7 B.1.1.7 lineage B.1.351 binding cellular response comparable Complete coronavirus coronavirus disease Coronavirus disease-19 COVID COVID-19 dose effective Efficacy G614 variant helper cell Humoral immunity Immunity immunogenicity IMPROVE independent independent of Lineage magnitude neutralization neutralizing antibody Neutralizing antibody response neutralizing antibody responses NHP NHPs pandemic Protective regimen regimens respiratory SARS-CoV-2 spike sera single dose T helper cell Th cell two-dose regimen upper respiratory tract Vaccine variants variants of concern was reduced while
[DOI] 10.1084/jem.20202756 PMC 바로가기 [Article Type] Article

A persistent epidemic of porcine epidemic diarrhoea virus infection by serological survey of commercial pig farms in northern Vietnam

Research Article

Published on 2021-07-052022-10-28
Journal: BMC veterinary research [Category] Coronavirus,

Nationwide Seroprevalence of SARS-CoV-2 in Saudi Arabia

사우디 아라비아에서 SARS-CoV-2의 전국적인 유행성

Article

Published on 2021-07-012022-09-12
Journal: Journal of infection and public health [Category] MERS, SARS, 진단,

[키워드] addition antibody Asymptomatic Biochemistry caused co-morbidity collected COVID-19 COVID-19 cases COVID-19 infection COVID-19 pandemic COVID-19 patients Critical demographics determine estimate Estimated estimates Evidence groups Hail HCW HCWs healthcare worker healthy blood donor healthy blood donors hypertension in-house ELISA indicate Infection Jeddah Kingdom lab Mild National Non-COVID-19 pandemic Patient positive control Prevalence prevalence of COVID-19 reactive Region regions reported respiratory RT-PCR SARS-CoV-2 SARS-CoV-2 seroprevalence Saudi Arabia sera serological Seroprevalence serum sample serum samples statistical subset virus spread
[DOI] 10.1016/j.jiph.2021.04.006 PMC 바로가기 [Article Type] Article

Presence and strength of binding of IgM, IgG and IgA antibodies against SARS-CoV-2 during CoViD-19 infection

CoViD-19 감염 중 SARS-CoV-2에 대한 IgM, IgG 및 IgA 항체의 존재 및 결합 강도

Article

Published on 2021-07-012022-09-12
Journal: Biosensors & bioelectronics [Category] SARS, 진단,

Multi-species ELISA for the detection of antibodies against SARS-CoV-2 in animals

동물에서 SARS-CoV-2에 대한 항체 검출을 위한 다종 ELISA

Article

Published on 2021-07-012022-09-11
Journal: Transboundary and emerging diseases [Category] MERS, SARS, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus animals antibody Antibody detection cattle caused chicken conditions coronavirus COVID-19 demonstrated diagnostic diagnostic specificity diagnostics disease ELISA ELISA protocol evaluated felines ferrets hamsters hosts Human Infection intermediate hosts mustelids natural infection outbreak outbreak investigations pandemic raccoon dog raccoon dogs RBD Receptor-binding domain referred to reported reservoir respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections Screen sensitivity sera serology Seroprevalence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 shown specificity susceptible the receptor-binding domain
[DOI] 10.1111/tbed.13926 PMC 바로가기 [Article Type] Article

Complement Anaphylatoxins and Inflammatory Cytokines as Prognostic Markers for COVID-19 Severity and In-Hospital Mortality

COVID-19 심각도 및 병원 내 사망률에 대한 예후 마커로서 아나필라톡신 및 염증성 사이토카인 보완

Immunology

Published on 2021-07-012022-09-11
Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커,

[키워드] Activation Analysis anaphylatoxin anaphylatoxins C3a C5a changes in chemokine chemokines clinical disease clinical outcomes complement complement anaphylatoxins Complement pathway complement system complications COVID-19 COVID-19 patient COVID-19 severity Critical critical COVID-19 patient critical COVID-19 patients critical patients cytokine Cytokine storm Cytokines deaths dysregulation enrolled enzyme-linked immunosorbent enzyme-linked immunosorbent assay healthy control healthy controls highlight Hospitalization IgM antibody IgM antibody levels IL-1β IL-6 IL-8 immunopathology In-hospital in-hospital mortality infected with SARS-CoV-2 Inflammatory cytokine Inflammatory cytokines Inflammatory mediators Innate immunity Interaction interleukin investigated mediators mild cases mild COVID-19 patients mild patient mild patients Mortality Necrosis outcome Patient patients patients with COVID-19 positively correlated Potential treatment Prognosis prognostic properdin Protein RANTES SARS-COV-2 infection SARS-CoV-2 infections SARS‐CoV‐2 SARS‐CoV‐2 sera serum severe SARS Signaling significantly significantly higher survival group target Treatment strategies treatment strategy Tumor tumor necrosis tumor necrosis factor upregulated utility were measured
[DOI] 10.3389/fimmu.2021.668725 PMC 바로가기 [Article Type] Immunology