Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity흔한, 저주파, 희귀 및 초희귀 코딩 변종은 COVID-19 심각성에 기여합니다Original Investigation Published on 2021-12-102022-09-10 Journal: Human Genetics [Category] SARS, 변종, 진단, [키워드] absence Analysis base coding variant cohorts common common variants contribute COVID-19 COVID-19 severity demonstrated diagnostics disease exonic feature Features Genetic GWAS host genetics identify independent information Linkage disequilibrium loci Logistic logistic regression model machine-learning management offer Pathway analysis positive individuals rare variant reflected SARS-CoV-2-positive individual score selected severity supplementary material the disease Therapeutics to define variant variants was used were used whole-exome sequencing with COVID-19 [DOI] 10.1007/s00439-021-02397-7 PMC 바로가기 [Article Type] Original Investigation
Presentation and evaluation of a modern course in disaster medicine and humanitarian assistance for medical studentsResearch Published on 2021-12-102022-10-28 Journal: BMC Medical Education [Category] Coronavirus, SARS, [키워드] Analysis Anesthesiology approach assistance carried clinic collected Complete Course crisis management cross-sectional curriculum deficiency determine develop disaster Disaster medicine Disaster preparedness curriculum effort evaluate expand female FIVE Germany Humanitarian assistance implementation indicate International knowledge limit male mandatory medical students Medicine National overcome pandemic physician presentation Previous studies Questionnaires Result shown significant increase supplementary material Survey/ questionnaires the SARS-CoV-2 Tübingen undergraduate medical education university were used [DOI] 10.1186/s12909-021-03043-6 PMC 바로가기 [Article Type] Research
Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency사례 시리즈: COVID-19 및 1차 항체 결핍 환자를 위한 회복기 혈장 요법Original Article Published on 2021-12-102022-09-12 Journal: Journal of Clinical Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] antibody appear applied benefit Clinical symptoms Cohort common variable immunodeficiency convalescent plasma convalescent plasma treatment country Course COVID-19 COVID19 patient deficiency demonstrated Effectiveness Evidence Fever Follow-up Hypogammaglobulinemia immunocompromised individual immunocompromised individuals inborn errors of immunity Infection longitudinal many case many cases monoclonal antibody Mutation one patient option Patient PCR plasma primary antibody Primary immunodeficiencies reduction in resolved risk Safe SARS-CoV-2 Sequencing Side effect supplementary material Therapeutic benefit Therapies treated Treatment viral genome Viral load Viral RNA shedding viral shedding while with COVID-19 [DOI] 10.1007/s10875-021-01193-2 PMC 바로가기 [Article Type] Original Article
Impact of visceral fat on the prognosis of coronavirus disease 2019: an observational cohort studyObservational Study Published on 2021-12-102022-10-04 Journal: BMC Infectious Diseases [Category] SARS, 임상, [키워드] 95% CI adipose association assumed AUC BMI body mass index characteristic Chest computed tomography Clarification Computed tomography confounders coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients COVID-19 prognosis Cox regression analysis death defined Disease progression elevated enrolled Evidence fat hazard ratio Health Impact incidence independent risk factor indicated individual investigated kidney mechanical ventilation morbidity morbidity and mortality nasal obesity Observational cohort study oxygen positive predict Predictive Prognosis progressed progression recent remained Respiratory failure Result risk factor severe acute respiratory syndrome coronavirus 2 severe COVID-19 severity significantly stages subjects supplementary material TAT tissue upper pole visceral Visceral adipose tissue with COVID-19 [DOI] 10.1186/s12879-021-06958-z PMC 바로가기 [Article Type] Observational Study
Numbers of close contacts of individuals infected with SARS-CoV-2 and their association with government intervention strategiesResearch Published on 2021-12-092022-10-28 Journal: BMC Public Health [Category] Coronavirus, SARS, [키워드] “contact tracing” “COVID-19” “interventions” “SARS-CoV-2” age analysed Analysis association associations assumption average binomial regression model breakpoint changes in close contact Cohort conducted confirmed case Contact Contact tracing decrease demographics epidemiological evaluate expected Government greater increases in indicated individual infected with SARS-CoV-2 information Intervention Ireland negative number provide reduction in Regression model reported Result secondary Separate supplementary material the mean Transmission [DOI] 10.1186/s12889-021-12318-y PMC 바로가기 [Article Type] Research
Parents’ pandemic NICU experience in the United States: a qualitative studyResearch Published on 2021-12-092022-10-28 Journal: BMC Pediatrics [Category] Coronavirus, SARS, [키워드] analyzed approach Care change collected concerning COVID-19 COVID-19 pandemic demonstrated distress emotional finding Healthcare provider hospital Infant Infants intensive care unit Interaction Isolation lack less neonatal intensive care unit NICU pandemic parent parental parents participant Qualitative question recruited reported Research response social media platform Stress Study design supplementary material the United State The United States [DOI] 10.1186/s12887-021-03028-w PMC 바로가기 [Article Type] Research
Characteristics of peripheral white blood cells in COVID-19 patients revealed by a retrospective cohort studyResearch Published on 2021-12-092022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, SARS, [키워드] analyzed association basophil branch changes in China city COVID-19 COVID-19 patient COVID-19 patients death died discharged eosinophil eosinophils glucocorticoid hematological Hematological change hospitalized COVID-19 patient immune response investigated Level lymphocyte Lymphocytes New non-survivor outcome Patient patients peripheral poor prognosis positive correlation predictor Prognosis proportion recruited Result retrospective cohort study SARS-COV-2 infection severe COVID-19 patient significantly lower subgroup analysis supplementary material survivor Survivors Tongji Hospital Treatment was performed White blood cell with COVID-19 Wuhan [DOI] 10.1186/s12879-021-06899-7 PMC 바로가기 [Article Type] Research
Implementing a low-threshold audio-only telehealth model for medication-assisted treatment of opioid use disorder at a community-based non-profit organization in Washington, D.C.Case Study Published on 2021-12-092022-10-31 Journal: Harm Reduction Journal [Category] Coronavirus, SARS, [키워드] age Buprenorphine calculate Care Characteristics comorbid condition COVID-19 COVID-19 pandemic diabete disorder drugs Effect Electronic health record flexible harm reduction Health Hepatitis HIV Human immunodeficiency virus hypertension Implementing IMPROVE Intervention lesson majority male Medication-assisted treatment Older Opioid use disorder pandemic Patient protocol Regulation remained reported supplementary material Support telehealth the patient Treatment USA Washington [DOI] 10.1186/s12954-021-00578-1 PMC 바로가기 [Article Type] Case Study
Epidemiological features of COVID-19 patients with prolonged incubation period and its implications for controlling the epidemics in ChinaResearch Published on 2021-12-092022-10-28 Journal: BMC Public Health [Category] COVID-19, SARS, [키워드] accelerated adjusted administration analyzed association China clinical feature Clinical practice Clinical severity COVID-19 COVID-19 case COVID-19 patient determinant disease onset elderly patients Epidemics epidemiological Evidence exceeded extreme feature implication Incubation period Level Local lower risk measure Patient Poisson regression model Prolonged incubation period provide quarantine reduced remained reported Result SARS-CoV-2 South supplementary material Transmissibility were used [DOI] 10.1186/s12889-021-12337-9 PMC 바로가기 [Article Type] Research
COVID-19 and medical education in Africa: a cross sectional analysis of the impact on medical studentsResearch Published on 2021-12-092022-10-28 Journal: BMC Medical Education [Category] Coronavirus, SARS, [키워드] administration Africa African Analysis approach caused change country COVID-19 COVID-19 pandemic cross decrease Degradation disease domain dropped flexible Health disparities healthcare highlight Impact impacts interactions medical education medical school medical students mental health pandemic participated Patient proportion regions Result Satisfaction supplementary material [DOI] 10.1186/s12909-021-03038-3 PMC 바로가기 [Article Type] Research