Starvation, Together with the SOS Response, Mediates High Biofilm-Specific Tolerance to the Fluoroquinolone Ofloxacin기아는 SOS 반응과 함께 Fluoroquinolone Ofloxacin에 대한 높은 생물막 특정 내성을 매개합니다Research Article Published on 2013-01-032022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] a minor age Amino acid amino acids antibiotic Antibiotic resistance Antibiotics Author Bacteria Bacterial biofilm carbon carbon source Community Concentration Critical demonstrated dependent on Escherichia coli exhibited functional greater growth hallmark heterogeneity heterogeneous Hypothesis identify infections influence lead leucine Medical devices microenvironment minor molecular mechanism molecular mechanisms multicellular Mutagenesis mutant mutants ofloxacin organism physiological physiological state planktonic random response significantly SOS SOS response starvation Stress stress response subpopulation subpopulations Support systemic infections Tolerance transposon [DOI] 10.1371/journal.pgen.1003144 PMC 바로가기 [Article Type] Research Article
Human Coronaviruses: Insights into Environmental Resistance and Its Influence on the Development of New Antiseptic StrategiesReview Published on 2012-11-122022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] acute respiratory syndrome aluminum antiseptic antiseptics-disinfectants Antiviral treatment approach Betacoronavirus biological fluids bronchitis children common cold Coronaviridae family coronavirus coronavirus described development different Efficacy emerging disease environmental condition environmental survival evaluate found HCoV 229E high risk HKU1 hospital Human human coronavirus human coronaviruses humans immunosuppressed patients Infection infections infective influence insight involved knowledge lack led to management mean methodology Neonates New NL63 nosocomial OC43 outbreak pathogen pathogenicity Pneumonia Prevent resistance respiratory diseases responsible RNA virus SARS-CoV specific treatment specificity Spread Strategy Support surgical temperature the Coronaviridae upper respiratory tract viral infections viruses [DOI] 10.3390/v4113044 PMC 바로가기 [Article Type] Review
SARS-CoV 9b Protein Diffuses into Nucleus, Undergoes Active Crm1 Mediated Nucleocytoplasmic Export and Triggers Apoptosis When Retained in the NucleusResearch Article Published on 2011-05-272022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] absence Affect Amino acid Apoptosis caspase-3 Cell cellular Critical death Degradation diffuse elevated export found host cell independent induce influence inhibitors interact Interaction Mediated NES NLS nuclear nuclear localization signal nucleus principal Protein SARS-CoV shown transiently transfected Transport Trigger [DOI] 10.1371/journal.pone.0019436 PMC 바로가기 [Article Type] Research Article