Analysis of SARS-CoV-2 antibodies in COVID-19 convalescent blood using a coronavirus antigen microarray코로나바이러스 항원 마이크로어레이를 이용한 코로나19 회복기 혈액 내 SARS-CoV-2 항체 분석Article Published on 2021-01-042022-09-10 Journal: Nature Communications [Category] 진단, 치료기술, [키워드] addition antibody Antibody Response Antibody responses Antigen antigens array Assay systems Blood blood specimens can be used clinical outcomes collected Combination Complete confirmed COVID-19 case convalescent coronavirus coronavirus strains COVID-19 COVID-19 diagnosis diagnosis of COVID-19 diagnostic Diagnostic markers disease ELISA Epidemiology human coronavirus human respiratory viruses immunologically include Infection MERS MERS-CoV Microarray nucleoprotein pandemic Patient PCR testing performed pharyngeal Prevalence profile Protein Protein array analysis Research respiratory respiratory specimen respiratory viruses risk SARS-CoV SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 pandemic SARS-CoV-2 PCR testing sera serologic specimen Spike protein symptomatic the disease the SARS-CoV-2 two groups viral infection [DOI] 10.1038/s41467-020-20095-2 PMC 바로가기 [Article Type] Article
Modelling the spread of SARS-CoV-2 pandemic – Impact of lockdowns & interventionsSARS-CoV-2 전염병 확산 모델링 - 폐쇄 및 개입의 영향Article Published on 2021-01-012022-09-12 Journal: The Indian journal of medical research [Category] MERS, 진단, [키워드] active infection antibody applied Asymptomatic cases asymptomatic patients basic reproduction number Clinical management Course COVID-19 pandemic death deaths disease spread healthcare hospital Immunity Impact increase in India initial Intervention less likelihood lockdown mathematical measure medication modelling parameter patients peaked Protective protocol reached reflect resources SARS-CoV-2 pandemic Serosurveys Spread statistical susceptible the disease Treatment strategies Vaccine virus transmission was reduced was used were used [DOI] 10.4103/ijmr.IJMR_4051_20 PMC 바로가기 [Article Type] Article
COVID-19 and Cancer Comorbidity: Therapeutic Opportunities and ChallengesCOVID-19와 암 동반질환: 치료의 기회와 도전Review Published on 2021-01-012022-09-10 Journal: Theranostics [Category] MERS, 신약개발, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect age anticancer approach Cancer cancer patient Cancer patients Care caused challenge choice Comorbidity confirmed cases coronavirus coronavirus disease Coronavirus disease 2019 Coronaviruses cough COVID-19 COVID-19 outbreak COVID-19 pandemic death disease disease severity Genome globe higher risk hospital Human Immunity individual infected individuals Infection Inflammation multidisciplinary approach Numerous opportunity pandemic pathophysiology Pathways produced reported Repurposed drug Repurposed drugs respiratory respiratory droplet Respiratory droplets Respiratory system risk SARS-CoV-2 SARS-CoV-2 pandemic signaling pathway sneezes Spread the SARS-CoV-2 treating COVID-19 Treatment viral disease Wuhan Wuhan, China [DOI] 10.7150/thno.51471 PMC 바로가기 [Article Type] Review
The impact of the SARS-CoV-2 pandemic on the mental health of hemodialysis patients in LebanonOriginal Article Published on 2021-01-012022-10-29 Journal: Journal of Medicine and Life [Category] COVID-19, SARS, [키워드] Alzheimer’s disease Anxiety Chronic hemodialysis COVID-19 COVID-19 epidemic cross-sectional dialysis Factor Hemodialysis impacted incidence information Kidney disease limitation majority males mandatory measure median age mental health pandemic Patient patients performed prevalent preventive measure questionnaire SARS-CoV-2 pandemic significantly more Stress Support the SARS-CoV-2 Treatment were excluded [DOI] 10.25122/jml-2020-0165 PMC 바로가기 [Article Type] Original Article
Exploring the magic bullets to identify Achilles’ heel in SARS-CoV-2: Delving deeper into the sea of possible therapeutic options in Covid-19 disease: An updateSARS-CoV-2에서 아킬레스건을 식별하기 위한 마법의 총알 탐색: Covid-19 질병에서 가능한 치료 옵션의 바다 더 깊이 탐구: 업데이트Review Published on 2021-01-012022-09-11 Journal: Food and chemical toxicology : an international jo [Category] SARS, 신약개발, 치료제, [키워드] Achille acting approach biologics Biophysics caused concerning condition COVID-19 Critical drug drug design Drug discovery Drug testing fatality feature food Food and nutrients genomic highlight Host host cell identify include information inhibit life cycle mechanisms morphology multiple organ failure natural natural products Organ failure pandemic pathophysiology plethora Protein target proteomics reaction Reactions Repurposed drugs Safe SARS-CoV-2 SARS-CoV-2 life cycle SARS-CoV-2 pandemic Stage stages status Symptom target the SARS-CoV-2 therapeutic option treat Vaccines [DOI] 10.1016/j.fct.2020.111887 PMC 바로가기 [Article Type] Review
Body Composition in Community-Dwelling Older Adults Before and After SARS-CoV-2 Infection: A Longitudinal Prospective Study in a Rural Village Struck by the PandemicSARS-CoV-2 감염 전후의 지역사회 거주 노인의 체성분: 전염병에 휩싸인 농촌 마을의 종단적 전향적 연구Article Published on 2021-01-012022-09-11 Journal: Journal of primary care & community health [Category] 치료기술, [키워드] Abnormalities abnormality Adults association baseline Body body composition can not change changes in Community contributed covariates COVID-19 decrease dietary habit dietary habits dynapenia enrolled Follow-up independent individuals linear mixed model logistic regression model longitudinal Longitudinal data multivariate Older Older adults pandemic physical activity population study predicted previous study Prospective random-effect Regression model rural communities sarcopenia SARS-CoV-2 SARS-CoV-2 antibodies SARS-COV-2 infection SARS-CoV-2 pandemic serological serological test Serological tests seropositive Seropositivity Struck by Study design susceptibility the SARS-CoV-2 Village worsening [DOI] 10.1177/21501327211047781 PMC 바로가기 [Article Type] Article
Development of potent and effective synthetic SARS-CoV-2 neutralizing nanobodies강력하고 효과적인 합성 SARS-CoV-2 중화 나노바디 개발Article Published on 2021-01-012022-09-12 Journal: mAbs [Category] 진단, [키워드] acute respiratory syndrome affected angiotensin-converting enzyme 2 antibody binding candidate cellular receptor characterized coronavirus coronavirus disease COVID-19 COVID-19 pandemic described development domain effective evaluated humanized in vivo nanobody neutralize Neutralizing neutralizing antibody Outbreaks phage display Prevent prophylactically respiratory virus responsible SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 spike the SARS-CoV-2 therapeutic therapeutic intervention toolkit viral infection virus wildtype [DOI] 10.1080/19420862.2021.1958663 PMC 바로가기 [Article Type] Article
Molecular docking studies of Indian variants of pathophysiological proteins of SARS-CoV-2 with selected drug candidates선택된 약물 후보를 사용한 SARS-CoV-2의 병태생리학적 단백질의 인도 변이체에 대한 분자 도킹 연구Article Published on 2021-01-012022-09-11 Journal: Journal of genetics [Category] 변종, 유전자 메커니즘, 치료제, [키워드] A97V ACE2 ACE2 binding binding Combination COVID-19 drug drug candidate drugs greater GRP78 hour India investigated involved molecular docking studies Molecular docking study Mutation Nsp12 Nsps P323L pandemic pathophysiological pathophysiology Protein SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 pandemic second selected spike Spike protein standstill subpopulation the SARS-CoV-2 genome therapeutic TMPRSS2 variant variants virus ΔΔG [DOI] 10.1007/s12041-021-01313-2 PMC 바로가기 [Article Type] Article
COVID-19 patients’ sera induce epithelial mesenchymal transition in cancer cells코로나19 환자 혈청, 암세포에서 상피 중간엽 전이 유도Article Published on 2021-01-012022-09-12 Journal: Cancer treatment and research communications [Category] 진단, [키워드] A549 cell applied bovine Cancer cancer cell cancer patient Cancer patients Cell cell culture experiment cells Clinical course connection consequence controls COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 pneumonia cytotoxicity dead diagnosed disease EMT epithelial experiments expression fetal Gene expression analysis healthy healthy volunteer Hospitalized Host Increased induce Infection Inflammation Interaction knowledge lack Metastasis mRNA levels nodule pathophysiology Patient patients performed persist proliferation Research SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic screened sera serum serum sample the lungs a thromboembolic processe translational VIM virus were recorded ZEB1 ZEB1, SNAIL2. [DOI] 10.1016/j.ctarc.2021.100406 PMC 바로가기 [Article Type] Article
Rationale for the Role of Heparin and Related GAG Antithrombotics in COVID-19 InfectionCOVID-19 감염에서 헤파린 및 관련 GAG 항혈전제의 역할에 대한 근거Review Published on 2021-01-012022-09-12 Journal: Clinical and applied thrombosis/hemostasis : offic [Category] 진단, [키워드] complex interplay complications COVID-19 danaparoid sodium disease GAG-antithrombotics heparin immune system management pathophysiology rationale reveal role SARS-CoV-2 SARS-CoV-2 pandemic sulodexide. Treatment [DOI] 10.1177/1076029620977702 PMC 바로가기 [Article Type] Review