Effects of COVID-19 lockdown on heart rate variabilityResearch Article Published on 2020-11-122022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] Activation Anxiety BSL changes in correlated correlation COVID-19 decrease Effect French Health HRV increase in lockdown men Non-invasive opposite orthostatic parameter parasympathetic participant Participants physical physical activity Psychological RCV reported response responses Result Stress Subjective two groups Variability variety women [DOI] 10.1371/journal.pone.0242303 PMC 바로가기 [Article Type] Research Article
Analyzing inter-reader variability affecting deep ensemble learning for COVID-19 detection in chest radiographsResearch Article Published on 2020-11-122022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] affecting Algorithm annotation approach benefit Characteristics Chest chest X-ray CNNs Coronavirus disease 2019 COVID-19 CXR deep learning disease estimation help highlight IMPROVE knowledge Level limitation parameter performance random region of interest ROI several limitations Simultaneous Stage statistical analysis Support truth Variability [DOI] 10.1371/journal.pone.0242301 PMC 바로가기 [Article Type] Research Article
Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibilityArticle Published on 2020-11-102022-10-04 Journal: Cell Discovery [Category] 변종, 유전자 메커니즘, 임상, 치료기술, [키워드] accounted Affect allele allele frequency Analysis association Asymptomatic Asymptomatic disease bioinformatics Chinese Chinese patient complex diseases conducted confounding factors COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 severity Critical Critically ill death disease severity DPP7 effort FIVE General population Genetic genetic architecture genetic study genetic variants Genome-wide association studies genomic GOLGA3 group help Host IL-1 ill patient Infection initial Interaction International involved Laboratory limitation locus loss of function manifestation Mechanisms of disease Mild missense variant moderate outbreak outcome Patient patients phenotypic provide Sequencing Severe patient severity Shenzhen signaling pathway significantly stability suggested susceptibility TMPRSS2 protein Variability variant whole-genome sequencing [DOI] 10.1038/s41421-020-00231-4 PMC 바로가기 [Article Type] Article
Bovine Coronavirus: Variability, Evolution, and Dispersal Patterns of a No Longer Neglected BetacoronavirusArticle Published on 2020-11-102022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] affecting approach bovine Bovine coronavirus clinical impact Cluster compensatory mutation Complete complex contrary coronavirus disease European Evidence evidenced Evolution favor Genome Host International Migration Mutation Neglected Occurrence other coronaviruses pathogen pattern phylodynamic phylodynamics phylogeography plasticity preventive measure Protein recombination rate reduce Respiratory disease Selection selective spike gene Spike protein Strains the United State tissue tropism vaccination Variability viral evolution viral genome viral tropism while [DOI] 10.3390/v12111285 PMC 바로가기 [Article Type] Article
Genomics in the era of COVID-19: ethical implications for clinical practice and public healthComment Published on 2020-11-092022-10-31 Journal: Genome Medicine [Category] COVID-19, SARS, [키워드] Clinical practice COVID-19 disease severity Ethics Factor Genomics highlight Host Host genomics implication patients with COVID-19 potential benefit public health susceptibility Variability [DOI] 10.1186/s13073-020-00792-9 PMC 바로가기 [Article Type] Comment
How to Minimize the Impact of Pandemic Events: Lessons From the COVID-19 CrisisShort Communication Published on 2020-11-052022-10-29 Journal: International journal of health policy and managem [Category] COVID-19, SARS, [키워드] acute respiratory syndrome addressed Affect Analysis applied approach causes characterized chose coronavirus coronavirus disease country COVID-19 crisis death death rate defined Health management high variability hospital Hospital Beds Hospital Stress Impact infected case Infection Italy lesson median age multivariable NHS number of infected outcome pandemic Pandemics predominant protocol Region regression analysis responsible SARS-CoV-2 statistical Stress System Variability [DOI] 10.34172/ijhpm.2020.115 PMC 바로가기 [Article Type] Short Communication
Public perceptions of the effectiveness of recommended non-pharmaceutical intervention behaviors to mitigate the spread of SARS-CoV-2Research Article Published on 2020-11-042022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 95% CI adjusted age bivariate analysis Characteristics conducted COVID-19 pandemic Critical cross-sectional survey Cutoff demographics disease effective Effectiveness effort female groups Health healthcare indicate Infection Intervention likelihood Measures mitigate multivariable logistic regression NPI participant physical Prevent Primary outcome Public public health threat reducing Regression model Research Result SARS-CoV-2 SARS-COV-2 infection severity severity of COVID-19 social distancing Spread Vaccine Variability variable washing hands white widespread [DOI] 10.1371/journal.pone.0241662 PMC 바로가기 [Article Type] Research Article
Explaining among-country variation in COVID-19 case fatality rateArticle Published on 2020-11-032022-10-29 Journal: Scientific Reports [Category] COVID-19, [키워드] Cancer center CFR changes in chronic respiratory disease Comorbidity Control country COVID-19 COVID-19 case COVID-19 mortality death death rate driver European Explaining Factor Fatality rate GDP highest hospital identify incidence increased risk individual level induces Infection key factor Metrics mortality rate Pathogens population level prevention progressed provided respiratory infections risk SARS-CoV-2 smoking Spread the epidemic trajectory used data Variability variable variables Variation viral infection while [DOI] 10.1038/s41598-020-75848-2 PMC 바로가기 [Article Type] Article
Performance of nucleocapsid and spike-based SARS-CoV-2 serologic assaysResearch Article Published on 2020-11-022022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] abrogated acute respiratory syndrome anti-SARS-CoV-2 antibodies Antibody test Antigen antigens cause component coronavirus COVID-19 ELISA ELISAs evaluated exhibiting False positive False-positive highest identification IgA IgG IgG and IgM IgM/IgG in some lateral flow non-specific novel nucleocapsid nucleocapsid IgM PCR-confirmed COVID-19 performance plasma antibody positive presence of antibody reaction reactivity reproducibility S1 IgG SARS-CoV-2 sensitivity Sensitivity and specificity serologic assay specificity spike IgG System target trimer Variability was used [DOI] 10.1371/journal.pone.0237828 PMC 바로가기 [Article Type] Research Article
Polyunsaturated fatty acid biosynthesis pathway and genetics. implications for interindividual variability in prothrombotic, inflammatory conditions such as COVID-19✰,✰✰,★,★★Research article Published on 2020-11-012022-10-05 Journal: Prostaglandins, Leukotrienes and Essential Fatty Acids [Category] SARS, 유전자 메커니즘, [키워드] Affect allele arachidonic acid biosynthesis pathway chromosome 11 circulating coding COVID-19 COVID-19 symptom Cytokine storm death Desaturation eicosanoid Europeans expression Fads gene cluster FADS1 fatty Fatty acid functional gene cluster Genetic genetics Haplotype healthy High dose higher risk Highly unsaturated fatty acids implication INDEL induce Inflammation inflammatory condition insertion Major modulation omega-3 pathological response physiological response polymorphism Population predict prothrombotic reduced Regulatory response Rs66698963 SARS-CoV SARS-CoV-2 selective Signaling thrombosis thrombotic tissue unsaturated Variability well [DOI] 10.1016/j.plefa.2020.102183 [Article Type] Research article