In Silico Prediction of Novel Inhibitors of SARS-CoV-2 Main Protease through Structure-Based Virtual Screening and Molecular Dynamic SimulationArticle Published on 2021-09-032022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] 3CLpro acute respiratory syndrome Analysis analyzed apo form binding affinity binding mode caused Compound compounds Consensus coronavirus dissimilarity drug target dynamic eight enzyme genomic Health hit identification in viral inhibit inhibitor inhibitors of SARS-CoV-2 Interaction M pro molecular molecular docking molecular dynamic simulation Mortality novel pandemic pharmacokinetic physiological predicted prediction protease Proteases protocol provide Replication SARS Coronavirus SARS-CoV-2 SARS-CoV-2 main protease screened Screening selected selective severe disease Simulation Structure Structure-based virtual screening Virtual screening virus [DOI] 10.3390/ph14090896 PMC 바로가기 [Article Type] Article
SARS-CoV-2 natural infection in animals: a systematic review of studies and case reports and series동물의 SARS-COV-2 자연 감염 : 연구 및 사례 보고서 및 시리즈의 체계적인 검토Meta-Analysis Published on 2021-09-022022-09-01 Journal: The Veterinary Quarterly [Category] Fulltext, SARS, 조류인플루엔자, 진단, [키워드] 95% CI 95% confidence interval analyses analyzed animals approach calculate Case report Case series cats COVID-19 COVID-19 pandemic Critical determine Diagnostic method diagnostic methods eight ELISA followed by Health highest Human immunochromatography implication literature review Meta-analysis MIA natural infection nine observational studies observational study one health performed Prevalence prevalence study Prevention and control proportion Quantitative random-effects model required RT-PCR SARS-CoV-2 SARS-COV-2 infection selected serological serological response Serological tests systematic review to define Transmission yielding zoonotic zoonotic disease [DOI] 10.1080/01652176.2021.1970280 PMC 바로가기 [Article Type] Meta-Analysis
Challenges in Preventive Practices and Risk Communication towards COVID-19: A Cross-Sectional Study in BangladeshArticle Published on 2021-09-022022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] 95% CI Adults Analysis Bangladesh challenge communication conducted COVID-19 cross-sectional survey Data analysis death determine division effective eight equipment Factor group help highest highlight identify information male measure multiple logistic regression negative influence pandemic Practice predictor Prevent Protective protective behavior protective behaviour Randomly Research resulting risk Risk communication second wave selected Sociodemographic was used [DOI] 10.3390/ijerph18179259 PMC 바로가기 [Article Type] Article
A scoping review on the changes in vascular surgical practice during the early phases of the COVID-19 pandemicReview article Published on 2021-09-012022-10-05 Journal: Seminars in vascular surgery [Category] SARS, 신약개발, [키워드] article changes in conditions conducted coronavirus disease COVID-19 COVID-19 pandemic early phase Effect eight Elective Surgical Procedure Emergencies extension groups Health services research Infection Ischemia item limb Local outcome pandemic Pandemics Patient provide reduce reported Reporting Research resource review risk of COVID-19 SARS-CoV-2 significant changes in surgical Topic Vascular [DOI] 10.1053/j.semvascsurg.2021.07.002 [Article Type] Review article
Validation of GeneXpert testing for SARS-CoV-2 RNA in eight hospital laboratories in Oman오만의 8 개의 병원 실험실에서 SARS-COV-2 RNA에 대한 유전자 테스트 검증Comparative Study Published on 2021-09-012022-09-01 Journal: The Pan African Medical Journal [Category] SARS, 진단, 치료기술, [키워드] aims Cepheid comparison coronavirus country COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients cross-sectional cross-sectional study Ct values diagnostic diagnostic testing E gene eight evaluate highlight hospital Kingfisher Laboratory Liferiver molecular N gene Nasopharyngeal swab nasopharyngeal swabs National Oman ORF ORF gene Patient performed point of care presenting Public public health emergency Roche routine diagnostic testing RT-PCR RT-PCR kit RT-PCR kits SARS-CoV-2 SARS-CoV-2 RNA Sensitivity and specificity specimens Swab Testing TIB MOL BIOL validation Viral Viral load viral loads was tested was used [DOI] 10.11604/pamj.2021.40.2.27224 PMC 바로가기 [Article Type] Comparative Study
Evolutionary insights into the furin cleavage sites of SARS-CoV-2 variants from humans and animals인간과 동물의 SARS-CoV-2 변이체의 푸린 절단 부위에 대한 진화론적 통찰력Article Published on 2021-09-012022-09-11 Journal: Archives of Virology [Category] SARS, 변종, 유전자 메커니즘, 진단, 치료기술, [키워드] Affect Alter Amino acid Analysis analyzed B.1.1.7 B.1.1.7 isolate B.1.351 B.1.429 B.1.429 + B.1.427 B.1.525 binding cell tropism circulating variants cleavage database Deletion deletions Effect eight except for FCS Frequency furin furin cleavage site genetic polymorphisms GISAID GISAID initiative Human initiative investigated isolates Laboratory motif Multiple Mutation mutations P.1 P681H pathogenicity Point mutation predicted prevalent Q677H SARS-CoV-2 spike protein SARS-CoV-2 variant sequence Seven shown significantly spike Spike protein Spike protein sequence Surveillance Transmissibility USA variant variants virus transmissibility [DOI] 10.1007/s00705-021-05166-z PMC 바로가기 [Article Type] Article
Nosocomial or not? A combined epidemiological and genomic investigation to understand hospital-acquired COVID-19 infection on an elderly care wardShort communication Published on 2021-09-012022-10-05 Journal: Infection Prevention in Practice [Category] 변종, [키워드] addition Analysis Asymptomatic Care Cluster cluster analysis cohort of patient Contact tracing contributing to COVID-19 COVID-19 infection eight epidemiological Epidemiology events Factor finding Genome sequencing genomic HCWs healthcare worker Hospital-acquired infection Hospitalized hospitals identify IMPROVE In-hospital increasingly Infection Infection prevention outbreak Patient performed polymerase chain positive SARS-CoV-2 transmission Sequencing Single nucleotide polymorphism Transmission two group viral genome Virological ward [DOI] 10.1016/j.infpip.2021.100165 [Article Type] Short communication
Coronavirus disease 2019 in patients with neuroendocrine neoplasms: Preliminary results of the INTENSIVE studyObservational Study Published on 2021-09-012022-10-05 Journal: European journal of cancer (Oxford, England : 1990 [Category] 임상, [키워드] acute respiratory syndrome analogue Antibiotics change characteristics of patient Chemotherapy Comorbidities coronavirus coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 diagnosis declined eight enrolled Fever intensive care investigator lack lung carcinoma material median age MOST Most patient Nasopharyngeal swab neoplasm neuroendocrine Neuroendocrine neoplasms Neuroendocrine tumours occurred overcome Patient patients patients died positive primary site receiving RT-PCR SARS-CoV-2 Specific Symptom tested Therapies therapy Treatment [DOI] 10.1016/j.ejca.2021.06.029 PMC 바로가기 [Article Type] Observational Study
Comparison of approaches to quantify SARS-CoV-2 in wastewater using RT-qPCR: Results and implications from a collaborative inter-laboratory study in CanadaRT-qPCR을 사용하여 폐수에서 SARS-CoV-2를 정량화하는 접근 방식의 비교: 캐나다의 공동 실험실 간 연구의 결과 및 의미Comparative Study Published on 2021-09-012022-09-11 Journal: Journal of environmental sciences (China) [Category] SARS, 치료기술, [키워드] 229E Aliquots Analysis approach approaches Canada Chain Reaction comparable Concentration condition coronavirus COVID-19 COVID-19 pandemic detection Effectiveness eight estimate evaluate expected fraction greater HCoV HCoV-229E human coronavirus implication inactivated Laboratory polymerase chain polymerase chain reaction protocol provided Public public health Quality Quality assurance Quality control Quantitative remained reported Result reverse transcription reverse transcription quantitative polymerase chain reaction RNA RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA Surrogates Surveillance tested Variability wastewater wastewater surveillance [DOI] 10.1016/j.jes.2021.01.029 PMC 바로가기 [Article Type] Comparative Study
Implementation of a COVID-19 cohort area resulted in no surface or air contamination in surrounding areas in one academic emergency departmentCOVID-19 코호트 지역의 구현으로 하나의 학술 응급실에서 주변 지역의 표면 또는 대기 오염이 발생하지 않았습니다.Article Published on 2021-09-012022-09-11 Journal: The American journal of emergency medicine [Category] SARS, 치료기술, [키워드] analyzed changed Cohort collected contagious Contamination COVID-19 COVID-19 cohort COVID-19 pandemic Department determine dissemination doffing donning E gene Effectiveness eight Emergency emergency department evaluate exit Face shield germicidal HCW Health care health care workers implementation individual Infection infection control measure minimal air N-95 Nurse Nurses Patient Patient care patients Personal protective equipment physician PPE PPE donning protocol protocols RT-PCR Sample SARS-CoV-2 Shield Spread the disease Viral sampling. zone [DOI] 10.1016/j.ajem.2021.04.082 PMC 바로가기 [Article Type] Article