sera – Page 57 – Communicable Diseases Research

DNA vaccination induced protective immunity against SARS CoV-2 infection in hamsterss

Research Article

Published on 2021-05-272022-10-28
Journal: PLoS Neglected Tropical Diseases [Category] COVID-19, SARS,

Kinetics of Neutralizing Antibodies of COVID-19 Patients Tested Using Clinical D614G, B.1.1.7, and B 1.351 Isolates in Microneutralization Assays

미세중화 분석에서 임상 D614G, B.1.1.7 및 B 1.351 분리주를 사용하여 테스트한 COVID-19 환자 중화 항체의 동역학

Article

Published on 2021-05-262022-09-01
Journal: Viruses [Category] SARS, 변종, 진단, 치료기술, 치료법,

A real-time and high-throughput neutralization test based on SARS-CoV-2 pseudovirus containing monomeric infrared fluorescent protein as reporter

적외선 형광단백단백을 리포터로 포함하는 SARS-CoV-2 유사바이러스 기반의 실시간 고처리량 중화시험

Research Article

Published on 2021-05-182022-09-10
Journal: Emerging Microbes & Infections [Category] SARS, 변종, 유전자 메커니즘, 진단,

[키워드] animals antibody autofluorescence biosafety biosafety level Biosafety Level 3 biosafety level 3 laboratory Conventional correlated country D614G D614G mutation develop disease severity dual Efficacy flow cytometry fluorescent green fluorescent protein humans Infection Laboratory level 2 level 3 limit live SARS-CoV-2 luciferase mechanism monomeric monomeric infrared fluorescent protein natural infection neutralization neutralization assays neutralization test neutralization titer Neutralizing antibodies pandemic Particles plaque reduction neutralization Protein pseudovirus pseudoviruses quantification reporter S1 protein SARS-CoV-2 SARS-CoV-2 neutralization SARS-CoV-2 pseudovirus sensitivity sera shedding shown Support survival time-consuming vaccination Vaccine vaccine efficacy Variability variant
[DOI] 10.1080/22221751.2021.1925163 PMC 바로가기 [Article Type] Research Article

Seroprevalence Surveys for Anti-SARS-CoV-2 Antibody in Different Populations in Taiwan With Low Incidence of COVID-19 in 2020 and Severe Outbreaks of SARS in 2003

2020년 COVID-19 발병률이 낮고 2003년 SARS 발병이 심한 대만의 다양한 인구에서 Anti-SARS-CoV-2 항체에 대한 혈청 유병률 조사

Immunology

Published on 2021-05-182022-09-11
Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료제,

[키워드] Abbott Abbott SARS-CoV-2 IgG acute respiratory syndrome anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody chemiluminescent immunoassay community transmission conducted country COVID-19 COVID-19 vaccine cross-reactivity cross-sectional determined by effective Elecsy Epidemic epidemiological exclusion False-positive frontline healthcare worker group healthy IgG antibodies IgG antibody immunoassay imperative Infection lateral flow immunoassay LINE outbreak pandemic participant Participants Population positive result Prevalence provide qRT-PCR respiratory risk Roche SARS SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV-2 seroprevalence sera Seroprevalence Severe acute respiratory syndrome Spread survey symptomatic patient Taiwan tested
[DOI] 10.3389/fimmu.2021.626609 PMC 바로가기 [Article Type] Immunology

Seropositivity in blood donors and pregnant women during the first year of SARS‐CoV‐2 transmission in Stockholm, Sweden

스웨덴 스톡홀름에서 SARS-CoV-2 전염 첫 해 동안 헌혈자와 임산부의 혈청 양성

Original Article

Published on 2021-05-182022-09-12
Journal: Journal of internal medicine [Category] SARS, 진단,

[키워드] affecting age All participants Antibody testing approach approaches B‐cell baseline Bayesian framework blood donor Blood donors carried clinical trial clinical trials Cohort community transmission comparable competent complement Control COVID‐19 dissemination FIVE glycoprotein healthy blood donor healthy blood donors healthy donor IgG response IgG responses independent individual Infection infections information intervals Karolinska University Hospital likelihood lockdown Metadata mild infection mRNA vaccination Neutralizing antibody response neutralizing antibody responses pandemic participant Participants population immunity pregnant women Prospective Study random Randomly RBD reached receptor‐binding domain recommendations registration number Result review sampling SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 spike SARS‐CoV‐2 screened second wave selected sera serology seropositive Seropositivity Seroprevalence setting study period Sweden Swedish Swedish Ethical Review Authority symptomatic tested These data titre titres trajectory Transmission trimer vaccination Vaccinations was used
[DOI] 10.1111/joim.13304 PMC 바로가기 [Article Type] Original Article

One-Stop Serum Assay Identifies COVID-19 Disease Severity and Vaccination Responses

원스톱 혈청 분석으로 COVID-19 질병 심각도 및 백신 접종 반응 확인

Article

Published on 2021-05-172022-09-11
Journal: ImmunoHorizons [Category] SARS, 진단, 치료법,

[키워드] Adults Anti-RBD IgG Antiviral binding domain caused characterization complexity Comprehensive Concentration convalescent COVID-19 patient COVID-19 COVID-19 vaccine COVID-19 vaccines Critical death Diagnosis differentiation disease domain healthy IgA IgG IgG level IgG levels IgM Immunity immunoassay infections Kinetics magnitude measure measurement Mild mRNA COVID-19 vaccines multiplex N protein N-terminal domain neutralization Patient patients plasmablast responses Previous studies prozone RBD reached Receptor binding domain response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid sera serum serum/plasma severe disease severity symptom onset the N protein
[DOI] 10.4049/immunohorizons.2100011 PMC 바로가기 [Article Type] Article

Mice Immunized with the Vaccine Candidate HexaPro Spike Produce Neutralizing Antibodies against SARS-CoV-2

Communication

Published on 2021-05-122022-10-28
Journal: Vaccines [Category] COVID-19,

SARS‐CoV‐2 antibodies: IgA correlates with severity of disease in early COVID‐19 infection

Research Article

Published on 2021-05-122022-10-04
Journal: Journal of medical virology [Category] SARS, 진단,

[키워드] acute respiratory syndrome Admitted Patient age age and sex analyses antibody Antibody testing association collected coronavirus coronavirus disease correlated COVID‐19 COVID‐19 infection COVID‐19 Critical Critical disease Day detectable Diagnosis disease disease severity duration of symptoms ELISA evaluate examined gold highest hospital hospitalized patient IgA IgA antibodies IgA level IgG IgG antibody IgG positivity IgM IgM antibody Immunoglobulin immunoglobulin A Infection Multiple regression observé Patient polymerase chain positive predominant remained SARS‐CoV‐2 SARS‐CoV‐2 sera serology serum sample Severity of disease Sex significant difference significantly Standard statistically Support Symptom tested
[DOI] 10.1002/jmv.27058 PMC 바로가기 [Article Type] Research Article

SARS-CoV-2 Spike Protein Stabilized in the Closed State Induces Potent Neutralizing Responses

Vaccines and Antiviral Agents

Published on 2021-05-072022-10-30
Journal: Journal of Virology [Category] COVID-19, SARS,

[키워드] ACE2 antibody B.1.351 binding conformational conformations described epitope expected Glycoproteins immune response Immunity immunization immunized include individuals induce inhibit Interaction long-lasting majority mRNA vaccine Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody response neutralizing response observation P.1 potent prefusion Prevent Protein raised RBD receptor Receptor binding domain receptor binding site recruit response robust S protein SARS-CoV-2 SARS-CoV-2 strains SARS-CoV-2 vaccine SARS-CoV-2 variants sequence sera spike Spike protein spikes stability state T cell response the antibody response the RBD the spike protein trimer trimeric S protein Vaccination strategy Vaccine Vaccines variants variants of concern viral spike protein virion
[DOI] 10.1128/JVI.00203-21 PMC 바로가기 [Article Type] Vaccines and Antiviral Agents

IgM and IgG Immunoreactivity of SARS-CoV-2 Recombinant M Protein

SARS-CoV-2 재조합 M 단백질의 IgM 및 IgG 면역반응성

Article

Published on 2021-05-072022-09-10
Journal: International Journal of Molecular Sciences [Category] SARS, 진단, 치료기술, 치료법,

[키워드] Antigen antigenic antigenicity C-terminal convalescent COVID-19 COVID-19 sera Critical diagnostic ELISA function host cells IgG IgG reactivity IgM IgM and IgG IgM reactivity immune response immunodominance immunoreactivity investigated involved M protein membrane N-terminal nucleocapsid pattern positive produced Protein Proteins provoke purified reactivity recombinant SARS-CoV-2 SARS-CoV-2 membrane protein SARS-CoV-2 virus sera serology test serum sample serum samples shown specific antibodies specific antibody the SARS-CoV-2 the SARS-CoV-2 virus Vaccine design virion virus infection western blot
[DOI] 10.3390/ijms22094951 PMC 바로가기 [Article Type] Article