Presence of SARS-CoV-2 RNA on Surfaces of Public Places and a Transportation System Located in a Densely Populated Urban Area in South AmericaBrief Report Published on 2021-12-232022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] acute respiratory syndrome analyzed Area association being cause coronavirus COVID-19 dissemination Ecuador environmental virus Frequently information monitoring positive Presence protocol provide Public public health prevention Quito RNA RNA virus RT-LAMP SARS-CoV-2 SARS-CoV-2 RNA South America Support surface System tested urban Viral RNA virus [DOI] 10.3390/v14010019 PMC 바로가기 [Article Type] Brief Report
Is Gut Involvement a Cause or Effect of COVID-19?Brief Communication Published on 2021-12-222022-10-30 Journal: The Malaysian Journal of Medical Sciences : MJMS [Category] COVID-19, [키워드] ACE2 angiotensin-converting enzyme 2 Asian bowel cause COVID-19 disorder dysregulation Effect Effects explain facilitate functional gastric atrophy gastrointestinal tract greater Gut gut microbiota homeostasis hypochlorhydria indicate infection rate Inflammatory response inhibitor Injury Involvement liver Prevalence receptor Research risk SARS-CoV-2 severity of COVID-19 Stool Symptom Transmission [DOI] 10.21315/mjms2021.28.6.14 PMC 바로가기 [Article Type] Brief Communication
SARS-CoV-2 Spike Protein Destabilizes Microvascular HomeostasisSARS-CoV-2 스파이크 단백질은 미세혈관 항상성을 불안정하게 합니다.Research Article Published on 2021-12-222022-09-10 Journal: Microbiology Spectrum [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] ACE2 ACE2 expression Activation adverse effect adverse effects Affect alveolar alveolar epithelial cell Analysis angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 Angiotensin II Apoptosis Aspirin bind blunt bradykinin calcium Calcium signaling caspase cause caused Cell Cell signaling cells Coagulopathies complex Concentration contribute contributing to COVID-19 COVID-19 disease decreased expression downregulation dysfunction Effect Endothelial cell endothelial cells Endothelial dysfunction enzymatic activity enzyme epithelial epithelial cells event Evidence exposure expressed Factor homeostasis immunofluorescence microscopy in vitro model increased expression indicated infects Inflammation Interaction Interference Intervention Krüppel limit lung lung tissue lung tissues Lungs mechanism molecules organ dysfunction Pathogenesis pathology primary human cells pro-inflammatory molecules rationale receptor reduce reduced Respiratory function SARS-CoV-2 SARS-CoV-2 infected individuals SARS-COV-2 infection Signaling significantly spike Spike protein suggested tested these cell These cells thought thrombotic Thrombotic events understanding uninfected Vascular viability [DOI] 10.1128/Spectrum.00735-21 PMC 바로가기 [Article Type] Research Article
Clinical evaluation of the SD Biosensor SARS-CoV-2 saliva antigen rapid test with symptomatic and asymptomatic, non-hospitalized patientsResearch Article Published on 2021-12-222022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] age analyzed Antigen asked Asymptomatic carried cause children clinical Complete Culture Cutoff Disabled disease early phase eligible enrolled evaluated for inclusion include individuals majority nasopharyngeal Nasopharyngeal swab participant Patient patients performance Population positive positive sample potential benefit presenting questionnaire ranged Rapid test recorded reported Result RT-PCR Saliva SARS-CoV-2 SARS-CoV-2 testing SD Biosensor sensitivity Sensitivity and specificity Sex Stress symptom onset symptomatic and asymptomatic the patient verbal virus was used without symptoms [DOI] 10.1371/journal.pone.0260894 PMC 바로가기 [Article Type] Research Article
Immune Responses in Pregnant Sows Induced by Recombinant Lactobacillus johnsonii Expressing the COE Protein of Porcine Epidemic Diarrhea Virus Provide Protection for Piglets against PEDV InfectionArticle Published on 2021-12-212022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Lactobacillus johnsonii (L. johnsonii) activate administration antibody Antigen cause Cell cellular immune responses COE COE antigen dendritic cell develop effective epidemic diarrhea epitope evaluated expressing humoral IgA IgG antibody IgM antibody immune protection immune responses immunomodulatory effect in vitro induced Infection Infectious disease intestinal lactobacillus maturation mucosal Neutralizing Oral Immunization Oral vaccine PEDV pregnant pregnant sow protection Protein recombinant response secretory immunoglobulin A serum IgG SIgA triggered vaccination Vaccine viral spike protein virus [DOI] 10.3390/v14010007 PMC 바로가기 [Article Type] Article
Evaluation of health-related quality of life of Covid-19 patients: a hospital-based study in South Central EthiopiaResearch Published on 2021-12-202022-10-31 Journal: Health and Quality of Life Outcomes [Category] COVID-19, SARS, [키워드] adjusted analysed Analysis Arsi Zone average can be used cause Clinical characteristics Comorbidity conducted confirmed case COVID-19 cross-sectional death Dexamethasone Elderly patient EQ-5D Ethiopia evaluate Factor Follow-up groups Health Hospital stay HRQoL intranasal IQR Kruskal–Wallis test manifestation Mann–Whitney U test median Mild Multiple linear regression Older oxygen Patient patients psychological treatment Quality of life questionnaire Result severe disease significantly lower Sociodemographic South Stata Study design Symptom the median Treatment treatment intervention utility Visual Analogue Scale were used Zimbabwe [DOI] 10.1186/s12955-021-01900-y PMC 바로가기 [Article Type] Research
Inhibition of SARS-CoV-2 infection in human iPSC-derived cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoarchitecture and beatingBiochemistry Published on 2021-12-202022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] 48 hours abrogate Affect arrhythmia cardiomyocyte cause Cell cell death chaperone condition consequence COVID COVID-19 patients described detrimental effect disrupt downregulating dysfunction expressed expression Frequency infect inhibition investigated IPSC myocarditis number of infected prevented pro-inflammatory cytokine Protective effects receptor reduced reducing reported SARS-CoV-2 SARS-COV-2 infection sigma-1 receptor survival therapeutic potential therapeutic target triggered viral particle [DOI] 10.7717/peerj.12595 PMC 바로가기 [Article Type] Biochemistry
Acute Hemorrhagic Myelitis in an Adolescent With COVID-19: A Case Report and Review of LiteraturePediatrics Published on 2021-12-202022-10-31 Journal: Cureus [Category] COVID-19, [키워드] addition Adolescent affecting cause children Coronavirus disease 2019 COVID-19 described diagnosed disease Fever Follow-up Hemorrhagic hemorrhagic myelitis Infection literature male Myelitis neurological manifestation paraplegia pediatric Prevent radiological report Respiratory system review SARS-CoV2 serious complication Urinary incontinence with COVID-19 [DOI] 10.7759/cureus.20553 PMC 바로가기 [Article Type] Pediatrics
Temporal Patterns of COVID-19-Associated Pulmonary Pathology: An Autopsy StudyPathology Published on 2021-12-192022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory distress age alveolar alveolar cell Autopsy Bulgaria cause Cell change changes in clinical complication clinically Cohort coronavirus COVID-19 criteria develop disease disease onset distress Endotheliitis Endothelitis expired female fibrosis Gross Hematoxylin and eosin Histopathology hyaline membrane independent Infection interstitial light microscopy long-lasting lung changes Lungs male manifested Marina material mechanism morbidity and mortality notable Novel coronavirus novel coronavirus disease pathology Patient pattern polymerase chain Probability pulmonary pulmonary morphology Pulmonary pathology respiratory tract Result SARS-CoV-2 selected severe complication severe COVID-19 severe disease severity significantly increased squamous cell metaplasia symptom onset syndrome Temporal the disease the mean Type II pneumocyte university variant Varna Vascular withdrawn [DOI] 10.7759/cureus.20522 PMC 바로가기 [Article Type] Pathology
COVID-19 Vaccinations: Perceptions and Behaviours in People with Primary Ciliary DyskinesiaArticle Published on 2021-12-172022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome cause changed changes in cohort study coronavirus country COVID-19 COVID-19 vaccination dyskinesia effort female genetic disease group higher risk information International median pandemic participant PCD Perception primary ciliary dyskinesia questionnaire reported respiratory infections SARS-CoV-2 severe coronavirus disease Side effect Side effects social contact study population Support used data vaccination Vaccinations Vaccine [DOI] 10.3390/vaccines9121496 PMC 바로가기 [Article Type] Article