Clinical and cardiac magnetic resonance findings in post-COVID patients referred for suspected myocarditis심근염이 의심되는 post-COVID 환자의 임상 및 심장 자기 공명 소견Original Paper Published on 2021-08-262022-09-12 Journal: Clinical Research in Cardiology [Category] MERS, 진단, [키워드] Abstract Acute myocarditis Antibody titer Biomarkers cardiac assessment Cardiac imaging Chest chest pain clinical Course COVID patient COVID-19 COVID-19 disease Diagnosis disease ECG edema eight Ejection fraction elevated fatigue females fibrosis Final FIVE healthy heart disease hospital Inflammation lab Lake left Mild MR-tomography Myocardial Myocardial inflammation myocardial injury myocardial involvement myocarditis objective Patient patients positive Prevalence reported Result SARS-CoV-2 Shortness of breath suggested Symptom Thoracic Treatment ventricular [DOI] 10.1007/s00392-021-01929-5 PMC 바로가기 [Article Type] Original Paper
SARS-CoV-2 infection and transmission in school settings during the second COVID-19 wave: a cross-sectional study, Berlin, Germany, November 2020두 번째 COVID-19 물결 동안 학교 환경에서 SARS-CoV-2 감염 및 전파: 횡단면 연구, 독일 베를린, 2020년 11월Research Published on 2021-08-262022-09-10 Journal: Eurosurveillance [Category] MERS, SARS, 치료기술, [키워드] 95% CI 95% confidence interval adolescents affected affecting Asymptomatic attack rate balancing benefit Berlin Blood Blood samples case-contact children collected COVID-19 COVID-19 pandemic cross-sectional eight ELISA examined Germany household Households IgG antibodies IgG antibody individuals Infection infection prevalence infection risk infection risks Measures nine occurred Participants Prevalence preventive measure preventive measures Randomly required Result risk RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections School school attendance Schools Secondary infection secondary infections secondary school selected Swab Transmission with infection [DOI] 10.2807/1560-7917.ES.2021.26.34.2100184 PMC 바로가기 [Article Type] Research
Seroprevalence and risk factors of SARS-CoV-2 infection in an urban informal settlement in Nairobi, Kenya, December 20202020년 12월 케냐 나이로비의 도시 비공식 정착촌에서 SARS-CoV-2 감염의 혈청유병률 및 위험 요소Article Published on 2021-08-262022-09-12 Journal: F1000Research [Category] MERS, SARS, 진단, [키워드] 95% CI accounted affected age age and sex antibody Blood children Clustering conducted Consent COVID-19 COVID-19 pandemic COVID-19 vaccine determine distribution eight estimate highlight Households identify IgM IgM and IgG implementation individual individuals infection to SARS-CoV-2 Infectious disease Kenya Kibera Logistic regression measure Measures member participant population-based provided public health Randomly relative risk factor SARS-CoV-2 SARS-COV-2 infection selected serology seropositive Seroprevalence seroprevalence survey Serosurvey serum Sex significantly increased specimen Spike protein statistically significant Surveillance tested the SARS-CoV-2 urban urban informal settlement. was obtained was used yielding [DOI] 10.12688/f1000research.72914.2 PMC 바로가기 [Article Type] Article
Persisting symptoms three to eight months after non-hospitalized COVID-19, a prospective cohort studyResearch Article Published on 2021-08-262022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] affecting age analyzed association average baseline Cohort control group cough COVID-19 COVID-19 disease COVID-19 patients demographics Deterioration determinant eight Follow-up follow-up time Gender Health Infection Laboratory multivariate logistic regression participant Patient patients positive proportion prospective cohort study question questionnaire reported returned risk factor SARS-CoV-2 SARS-CoV-2 testing sore Symptom Symptoms syndrome the SARS-CoV-2 worsening [DOI] 10.1371/journal.pone.0256142 PMC 바로가기 [Article Type] Research Article
The CircumVent Project: a CPAP/O 2 helmet solution for non-invasive ventilation using an implementation research frameworkStudy Protocol Published on 2021-08-262022-10-30 Journal: Implementation Science Communications [Category] COVID-19, [키워드] Action Acute respiratory failure build COVID-19 COVID-19 pandemic COVID-19 patient CPAP death in COVID-19 develop eight evaluate feasibility Health health worker healthcare healthcare worker high-flow oxygen therapy implementation Implementation science include Infection Invasive mechanical ventilation Isolation mechanical ventilation Nigeria Non-invasive non-invasive ventilation occur oxygen supply patients with COVID-19 Pilot test Pneumonia positive airway pressure Promoting protocol recruit Registered Research respiratory diseases risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2, COVID-19 infection service steering committee Support treat Treatment ventilator [DOI] 10.1186/s43058-021-00193-y PMC 바로가기 [Article Type] Study Protocol
Molecular epidemiology of a familial cluster of SARS-CoV-2 infection during lockdown period in Sant Kabir Nagar, Uttar Pradesh, IndiaShort Paper Published on 2021-08-252022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, [키워드] Asymptomatic clinical sample Cluster Community Complete demonstrated eight Epidemiology familial cluster genome sequence index case India individual Infection transmission Kabir Lineage lockdown Next-generation sequencing Phylogenetic analysis provided restriction retrieved SARS-CoV-2 SARS-COV-2 infection similarity Spread Symptoms tested Travel Uttar Pradesh Wuhan strain [DOI] 10.1017/S0950268821001989 PMC 바로가기 [Article Type] Short Paper
Assessment of knowledge, attitude and practices among dental practitioners on methods of infection control while carrying out dental procedures during novel coronavirus (COVID-19) pandemicResearch Published on 2021-08-242022-10-28 Journal: The Pan African Medical Journal [Category] COVID-19, MERS, [키워드] 95% CI assessment body temperature Care contagious COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 virus demographic characteristics dental practitioner dentist dentists eight female hygiene independent variable India individual infection control knowledge likelihood Logistic regression analysis logistic regression model male measure Modification multivariable Novel coronavirus pandemic participant patient triage patients PPE Practice professional protocols question questionnaire recorded Result Study participants [DOI] 10.11604/pamj.2021.39.265.29003 PMC 바로가기 [Article Type] Research
Accelerated first-in-human clinical trial of EIDD-2801/MK-4482 (molnupiravir), a ribonucleoside analog with potent antiviral activity against SARS-CoV-2SARS-COV-2에 대한 강력한 항 바이러스 활성을 갖는 리보 뉴 클레오 사이드 유사체 인 EIDD-2801/MK-4482 (Molnupiravir)의 최초 인간 임상 시험의 가속화 된 인간 임상 시험.Randomized Controlled Trial Published on 2021-08-232022-08-13 Journal: Trials [Category] MERS, 임상, 치료제, [키워드] accelerated Accelerated start-up acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration Antiviral antiviral activity antiviral agent approval causative agent Clinical data clinical trial Cohort cohorts collaboration Complete completion contract research organization coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CRO daily dose described dose Dose escalation Dosing double-blind drug eight Escalation ethics committee fasted or fed state FDA FIH FIH study followed by food food-effect global pandemic healthy volunteer healthy volunteers initial initiated MAD MAD cohort MAD cohorts Medicine Medicines Medicines and Healthcare products Regulatory Agency MHRA molnupiravir multiple ascending dose Painter pharmacokinetic Phase 2 phase 2 dosing Phase 2 study phase 2/3 Phase I Placebo profile protocol Randomized REC receive receiving Regulatory Regulatory Authorities regulatory authority Research Ethics Research Ethics Committee respiratory Ribonucleoside analog SAD cohort Safe SARS-CoV-2 sequence Seven severe acute respiratory syndrome Coronavirus single ascending dose Sponsor subject submission supported timelines Tolerability United Kingdom US Food and Drug Administration were dosed working [DOI] 10.1186/s13063-021-05538-5 PMC 바로가기 [Article Type] Randomized Controlled Trial
Revelation of Potent Epitopes Present in Unannotated ORF Antigens of SARS-CoV-2 for Epitope-Based Polyvalent Vaccine Design Using Immunoinformatics Approach면역정보학 접근법을 사용한 에피토프 기반 다가 백신 디자인을 위한 SARS-CoV-2의 주석이 없는 ORF 항원에 존재하는 강력한 에피토프의 계시Immunology Published on 2021-08-232022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 변종, 신약개발, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus allele Analysis antigen expression antigenic B-cell B-cell epitope B-cell epitopes canonical Canonical protein epitopes carried CD4+ T-cell CD8+ T-cell conformational coronavirus Coverage eight epitope epitope-based polyvalent vaccine Epitopes expressed FIVE followed by highest HLA I supergroups immunodominant immunogenic kill linear linear B-cell epitope linear B-cell epitopes linkers Mutation mutations N-protein Open reading frame open reading frames ORF ORF3c ORF7a Orf9b overlap Polyvalent potent present Protein Region regions respiratory revelation SARS-CoV-2 scenario severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spike protein T-cell T-cell epitope T-cell epitopes the spike protein uORFs Vaccine variant variants [DOI] 10.3389/fimmu.2021.692937 PMC 바로가기 [Article Type] Immunology
Integrated single-cell analysis unveils diverging immune features of COVID-19, influenza, and other community-acquired pneumoniaResearch Article Published on 2021-08-232022-10-31 Journal: eLife [Category] COVID-19, MERS, [키워드] Analysis approach caused CD8 Cell Characteristics Cohort community-acquired pneumonia control subjects controls COVID-19 disease dysregulated eight etiology expand feature host response Human immune Influenza lack monocyte mononuclear cell natural killer cell non-infectious Pathogens Patient patients with COVID-19 PBMC performed Peripheral blood peripheral immune response phenotypic Pneumonia proteomic SARS-CoV-2 single-cell transcriptional transcriptomic type I unique [DOI] 10.7554/eLife.69661 PMC 바로가기 [Article Type] Research Article