Understanding COVID-19: From Dysregulated Immunity to Vaccination Status QuoImmunology Published on 2021-11-112022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] 2019-nCoV acute respiratory syndrome animal models beta-coronavirus coronavirus coronavirus disease COVID-19 cross death dysregulated immune response etiological agent experimental model experimental models immune responses Infectious disease Novel viruses Personalized medicine public health SARS-CoV-2 status understanding Vaccine Vaccine development [DOI] 10.3389/fimmu.2021.765349 PMC 바로가기 [Article Type] Immunology
Comparative analysis of the diagnostic performance of five commercial COVID-19 qRT PCR kits used in India인도에서 사용되는 5 개의 상업용 CovID-19 QRT PCR 키트의 진단 성능의 비교 분석Article Published on 2021-11-102022-09-01 Journal: Scientific Reports [Category] MERS, 진단, 치료기술, [키워드] 2019-nCoV amplified assays clinical clinical samples clinically collected Comparative analysis Contact contact with control group control patients controls correlation Council COVID-19 criteria Ct values diagnosed diagnostic diagnostic testing disease Diseases evaluate evaluated feature FIVE followed by healthy healthy individual healthy individuals heterogeneity highest inclusion criteria India individual initial Medical research Microbiology Molecular biology other respiratory virus Other respiratory viruses pandemic Patient PCR Poor positive protocol provided Quality assurance respiratory Respiratory samples respiratory viral infections respiratory viruses RNA extraction routine diagnostic testing RT-PCR RT-PCR kit sample collection SARS-CoV-2 Sensitivity and specificity symptomatic TaqPath Viral Viral load viral loads Virology viruses were used [DOI] 10.1038/s41598-021-00852-z PMC 바로가기 [Article Type] Article
Assessment of community psycho-behavioral responses during the outbreak of novel coronavirus (2019-nCoV): a cross-sectional studyResearch Article Published on 2021-11-092022-10-27 Journal: AIMS Public Health [Category] COVID-19, [키워드] 2019-nCoV addressed analyzed Anxiety anxiety symptoms assessment collected collected data Community conducted coronavirus cross-sectional demographic data female GAD-7 group highlight Infection information International knowledge management measure Mild moderate Novel coronavirus Older outbreak Participants personal health Precaution precautions preventive measure promote proportion Protective Psychological psychological Impact psychological need public health emergency questionnaire reported respondent response Result resulting Spread statistically the disease the epidemic Transmission unlikely [DOI] 10.3934/publichealth.2022003 PMC 바로가기 [Article Type] Research Article
460. Disproportionalities in COVID-19 Clinical Drug Trials in the United States: A Systematic Literature ReviewPoster Abstracts Published on 2021-11-042022-10-29 Journal: Open Forum Infectious Diseases [Category] COVID-19, [키워드] 2019-nCoV African American age Arm ARMS calculated Caucasian patient clinical clinical trial clinical trials Combination Controlled trial COVID-19 COVID-19 infection COVID-19 patient death demographic demographic characteristics Descriptive statistics drug eligible English language enrolled Ethnic groups females FIVE for inclusion Gender Generalizability Hospitalization hospitalized patient identify limit literature literature review male median age MOST National Older participant Participants Patient performed pharmacologic treatment placebo-controlled race Randomized controlled trial reported Result review Safe SARS-CoV-2 study cohort was performed white with COVID-19 [DOI] 10.1093/ofid/ofab466.659 PMC 바로가기 [Article Type] Poster Abstracts
491. Persistence of SARS-CoV-2 Iinfection in Immunocompromised ChildrenPoster Abstracts Published on 2021-11-042022-10-29 Journal: Open Forum Infectious Diseases [Category] COVID-19, [키워드] 2019-nCoV 24 hour age Asymptomatic CDC center Chi-square children Clinical characteristics clinical testing Cohort Comorbidity conducted consecutive negative test consultant Control Ct value cycle threshold defined diagnose DiaSorin evaluated Factor figure Fisher had more hospital Immunocompromised immunocompromising condition immunodeficiency Immunosuppressive treatment Implications inclusion criteria infection control initial IQR Kaplan-Meier curve Latinx log-rank test lymphopenia male median median time moderate MOST negative test no difference no significant difference outcomes Panel Patient PCR pediatric persistence Pfizer platform plot polymerase chain reaction positive Positive test potential transmission Primary outcome Result retrospective cohort study risk RT-PCR Samuel SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR test SARS-CoV-2 PCR testing SARS-CoV-2 viral SAS shown specific diagnoses subsequent symptomatic temporal dynamics tested timeline unique Viral load viral loads viral persistence were used Wilcoxon test [DOI] 10.1093/ofid/ofab466.690 PMC 바로가기 [Article Type] Poster Abstracts
Natural spring water gargle and direct RT-PCR for the diagnosis of COVID-19 (COVID-SPRING study)COVID-19 진단을 위한 천연 샘물 가글 및 직접 RT-PCR (COVID-SPRING 연구)Article Published on 2021-11-012022-09-11 Journal: Journal of Clinical Virology [Category] SARS, 치료기술, [키워드] 2019-nCoV 95% CI 95% confidence interval acceptability Accessibility asymptomatic individual Asymptomatic individuals choice clinical sensitivity collected Community Concentration consumables coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 cases Critical Cycle threshold values Diagnosis diagnosis of COVID-19 elements Frequency gargle healthcare worker limit Nasopharyngeal swab natural pandemic PCR reflected respiratory viral infections room temperature RT-PCR Saliva SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA sensitivity significantly lower simplicity specimen Swab symptomatic temperature unique Viral RNA water [DOI] 10.1016/j.jcv.2021.104995 PMC 바로가기 [Article Type] Article
Relevance between COVID-19 and host genetics of immune responseReview article Published on 2021-11-012022-10-05 Journal: Saudi Journal of Biological Sciences [Category] 유전자 메커니즘, [키워드] 2019-nCoV ACE2 ACEAngiotensin Converting Enzyme Activation acute respiratory syndrome Affect allele frequency Alter alveolar angiotensin angiotensin converting enzyme Antigen presentation antigenic antigenic peptide association binding caused CD4+ CD8+ cellular immunity change changes in China complications coronavirus disease COVID-19 cytokine secretion death disease Endoplasmic reticulum expressed expression expression data expression level Gas exchange gene product Genes Genetic Genotype HBVHepatitis B virus HCVHepatitis C virus Hepatitis B virus hepatitis C virus high mortality highlight HIVhuman immunodeficiency virus HLA HLA class I HLA gene HLAHuman leukocyte antigen host genetics Human immunodeficiency virus human leukocyte antigen immune immune response impair Infection Lungs MHC class I Non-small cell lung carcinoma NSCLCNon-small cell lung carcinoma outbreak pathogen Pathogenesis peptide phenotype pneumocyte Pneumocytes polymorphism populations precursor present antigen progression RASRenin-angiotensin system Relevance renin-angiotensin system reported responsible resulting SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARSSevere Acute Respiratory Syndrome Severe acute respiratory syndrome severe hypoxia Single nucleotide polymorphism SNPSingle nucleotide polymorphism Spread susceptibility T lymphocytes T-cell responses T-cells variant Variation viral entry viral infection virus virus spike protein viruses Wuhan [DOI] 10.1016/j.sjbs.2021.07.037 [Article Type] Review article
Comparative Sensitivity of Rapid Antigen Tests for the Delta Variant (B.1.617.2) of SARS-CoV-2SARS-COV-2의 델타 변이체 (B.1.617.2)에 대한 빠른 항원 시험의 비교 민감도Comparative Study Published on 2021-10-292022-09-01 Journal: Viruses [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] 2019-nCoV Antigen B.1.617.2 cartridge Comparative COVID-19 COVID19 Delta delta variant Diagnosis examined Fuji individual Infectious virus Influenza Japan lateral flow immunoassay Lateral flow immunoassays less mind nCoV pfu Rapid rapid antigen test Rapid antigen tests Rapid test RAT RATs SARS-CoV-2 SARS-CoV-2 antigen sensitivities sensitivity specimen Test tested the SARS-CoV-2 variant variety virus [DOI] 10.3390/v13112183 PMC 바로가기 [Article Type] Comparative Study
Reliable Diagnostics of SARS-CoV-2 Infections Using One- and Two-Gene Molecular Tests for a Viral RNA Detection—Results Questioning Previous ObservationsArticle Published on 2021-10-052022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] ORF1ab gene S gene 2019-nCoV Anatolia BD MAX™ System Becton Dickinson Biotechnology carried COVID-19 detection discrepancy E gene East effective evaluate evaluated Frequency Genes Inc. İstanbul new virus nine novel observation PCR positive product researcher RNA RNA detection SARS-CoV-2 SARS-CoV-2 RNA detection SARS-CoV-2 S gene sensitivity Spain specimens Spread statistically significant difference swabs System target gene Target genes Test the Coronaviridae time Turkey USA Viral RNA [DOI] 10.3390/diagnostics11101839 PMC 바로가기 [Article Type] Article
Cross-reactivity and inclusivity analysis of CRISPR-based diagnostic assays of coronavirus SARS-CoV-2Bioinformatics Published on 2021-10-012022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] 2019-nCoV absence acute respiratory syndrome Analysis analyzed assays Cas12 Cas13 Cas9 circulating Clinicians coronavirus coronavirus SARS-CoV-2 COVID-19 CRISPR cross-reactivity Diagnosis diagnostic diagnostic test Genome genome sequence help Host in silico information molecular Mutation mutations novel coronavirus disease organism Organisms pandemic pathogenic PCR performed polymerase chain protocol researchers SARS-CoV-2 SARS-CoV-2 sequence sequence sequence variability sequence variation Seven Strains target region the patient unique viral nucleic acid Viral RNA [DOI] 10.7717/peerj.12050 PMC 바로가기 [Article Type] Bioinformatics