Adaptive immune response – Page 6 – Communicable Diseases Research

Dynamic SARS-CoV-2-specific B-cell and T-cell responses following immunization with an inactivated COVID-19 vaccine

비활성화된 COVID-19 백신으로 예방접종 후 동적 SARS-CoV-2 특이적 B 세포 및 T 세포 반응

Article

Published on 2022-03-012022-09-11
Journal: Clinical microbiology and infection : the official [Category] SARS, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Adaptive immune response Adaptive responses affected age analysed B cell B cells booster dose CD4 CD4+ T cell CD8 CD8+ T cell Cell cells cellular response circulating Cohort CoronaVac coronavirus COVID-19 COVID-19 vaccine declined dose doses dynamic effector memory elicited first dose geometric mean geometric mean titre GMT Healthcare professional Human humoral IgA response IgG response IgG responses immune responses immunization implication inactivated Inactivated virus vaccine magnitude memory memory B memory B cell memory B cells memory CD4+ T cells memory CD8+ T cells naïve neutralization neutralizing activities offer peripheral B cells prospective cohort reached Receptor binding domain robust SARS-CoV-2 SARS-CoV-2 spike-specific SARS-CoV-2-specific antibodies SARS-CoV-2-specific B-cell serum severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specific antibodies subset sustained T cell T cell responses T cells T-cell Response terminally differentiated terminally differentiated effector memory cells timepoints vaccination Vaccine virus
[DOI] 10.1016/j.cmi.2021.10.006 PMC 바로가기 [Article Type] Article

Accuracy and real life performance of a novel interferon-γ release assay for the detection of SARS-CoV2 specific T cell response

Article

Published on 2022-03-012023-06-19
Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS,

[키워드] Adaptive immune response COVID-19 health care workers IFNγ release assay immunosuppressed patients T cell response test accuracy
[DOI] 10.1016/j.jcv.2022.105098 PMC 바로가기

Fighting the SARS-CoV-2 pandemic requires a global approach to understanding the heterogeneity of vaccine responses

Reviews

Published on 2022-02-242022-10-05
Journal: Nature Immunology [Category] COVID19(2023년), SARS, 비임상,

Three-Week Old Pigs Are Not Susceptible to Productive Infection with SARS-COV-2

Article

Published on 2022-02-102022-10-29
Journal: Microorganisms [Category] COVID-19,

Avian Orthoavulavirus Type-1 as Vaccine Vector against Respiratory Viral Pathogens in Animal and Human

Review

Published on 2022-02-082022-10-28
Journal: Vaccines [Category] COVID-19,

Extended interval BNT162b2 vaccination enhances peak antibody generation

Article

Published on 2022-01-272022-10-04
Journal: NPJ Vaccines [Category] 진단,

Age-associated SARS-CoV-2 breakthrough infection and changes in immune response in a mouse model

연령 관련 SARS-CoV-2 돌발 감염 및 마우스 모델의 면역 반응 변화

Coronaviruses

Published on 2022-01-242022-09-10
Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 유전자 메커니즘, 진단,

[키워드] adaptive Adaptive immune response addition age Antibody Response Breakthrough infection changes in COVID-19 COVID-19 mRNA Vaccination demonstrated effective higher risk immune breakthrough immune protection immune response immune responses individual individuals interferon investigated mechanism mice modulate Occurrence Older outcomes prevention strategies Primary infection Re-infection respiratory respiratory tract SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pathogenesis severe disease manifestation severe disease manifestations significantly susceptibility susceptible Treatment vaccination Vaccine vaccine breakthrough infection vaccine breakthrough infections virus replication wild-type
[DOI] 10.1080/22221751.2022.2026741 PMC 바로가기 [Article Type] Coronaviruses

Immune Profiling of COVID-19 in Correlation with SARS and MERS

Review

Published on 2022-01-172022-10-28
Journal: Viruses [Category] COVID-19, SARS,

[키워드] Adaptive immune response analyzed ARDS articles chemokine chemokines Clinical studies clinical trial coronavirus disease correlated COVID-19 COVID-19 pathogenesis cytokine Cytokine storm Cytokines death rate determine Disease diagnosis disease severity distress dosage dysregulated immune response Effect effective elevated Evidence highlight identify Immunosuppression infections inflammatory mediator information lack maintain management marker medication MERS MERS-CoV Patient profile Profiling provided regimen Research Respiratory illness responsible SARS-CoV SARS-CoV-2 SARS-CoV-2 pathogenesis shown syndrome therapeutic Treatment protocol Web of Science
[DOI] 10.3390/v14010164 PMC 바로가기 [Article Type] Review

Rapid Weight Loss, Central Obesity Improvement and Blood Glucose Reduction Are Associated with a Stronger Adaptive Immune Response Following COVID-19 mRNA Vaccine

Article

Published on 2022-01-052022-10-28
Journal: Vaccines [Category] COVID-19,

Resolution of viral load in mild COVID-19 patients is associated with both innate and adaptive immune responses

경증 COVID-19 환자의 바이러스 부하 해결은 선천 면역 반응 및 적응 면역 반응 모두와 관련이 있습니다

Article

Published on 2022-01-012022-09-11
Journal: Journal of Clinical Virology [Category] SARS, 변종, 신약개발, 유전자 메커니즘, 진단, 치료기술,

[키워드] absence acute phase Adaptive immune response all the patients antibodies antibody Asymptomatic characterized circulating collected Comorbidities Comorbidity COVID-19 COVID-19 patient COVID-19 patients Cytokines detectable dysregulation Efficiency elevated Factor had no hospitalized COVID-19 patient Host IgG IL-1β IL-6 IL-7 IL-8 immune response implicated in viral increase in Inflammation Inflammatory cytokine Inflammatory cytokines inflammatory mediator Inflammatory mediators innate immune response interferon Kinetics marker mediators mild COVID-19 patient mild infection Mild symptom mild symptoms Most patient Most patients neutralize Neutralizing antibodies neutralizing antibody no increase over Patient PRNT Receptor-binding domain Resolution respiratory respiratory sample Respiratory samples Saliva saliva samples SARS-CoV-2 SARS-CoV-2 viral load Seroconversion serum serum samples severe COVID-19 strain swab samples Symptom T-cell activation the patient the receptor-binding domain These data TNF-α Viral Viral load Viral RNA viral RNA detection virus isolate Virus neutralization
[DOI] 10.1016/j.jcv.2021.105060 PMC 바로가기 [Article Type] Article