Adult patients – Page 6 – Communicable Diseases Research

High flow nasal cannula for adult acute hypoxemic respiratory failure in the ED setting

응급실 환경에서 성인 급성 저산소성 호흡 부전을 위한 고유량 비강 캐뉼러

Review

Published on 2021-11-012022-09-11
Journal: The American journal of emergency medicine [Category] SARS, 임상,

Data automated bag breathing unit for COVID-19 ventilator shortages

COVID-19 인공호흡기 부족에 대한 데이터 자동화 백 호흡 장치

Research Articles

Published on 2021-10-182022-09-10
Journal: Intensive Care Medicine Experimental [Category] 비임상,

[키워드] ABBU acute respiratory distress syndrome Acute respiratory failure Adult patients animal model arterial blood arterial blood gases assist automated Bag Bag valve resuscitator baseline Bench breath breathing caused changes in clinical trial Compliance COVID-19 COVID-19 pandemic development Efficacy Emergency resuscitator etiology fixed followed by fraction injured lung Injury lung Lung injury lung lavage mechanical ventilator minute ventilation output oxygen oxygen flow oxygen flow rate Oxygenation PaO parameter Patient PEEP Physiological levels PIGS provide respiratory Respiratory failure respiratory rate Result saline lavage Tidal volume Treatment unit Ventilation ventilator Ventilator shortage Volume was increased was tested weight were measured
[DOI] 10.1186/s40635-021-00419-2 PMC 바로가기 [Article Type] Research Articles

Association Between Tumor Necrosis Factor Inhibitors and the Risk of Hospitalization or Death Among Patients With Immune-Mediated Inflammatory Disease and COVID-19

면역매개염증질환 및 코로나19 환자에서 종양괴사인자억제제와 입원 또는 사망 위험 간의 연관성

Research

Published on 2021-10-182022-09-12
Journal: JAMA Network Open [Category] MERS, SARS, 진단,

[키워드] 6-mercaptopurine 95% CI accounted accounting Adult patients age Analysis Arthritis association azathioprine category Clinical characteristics cohort study Combination conducted correlations country COVID-19 COVID-19 diagnosis Crohn disease data entry death demographic and clinical characteristics diagnose Diagnosis died Europe excluded exposure Factor female finding higher odd higher odds Hospitalization Hospitalized immune pathway Immune-mediated inflammatory disease Immune-mediated inflammatory diseases immunomodulatory Importance individual Inflammatory arthritis Inflammatory bowel disease Inflammatory diseases inhibitor International Janus kinase Kinase inhibitor lower risk measure methotrexate monotherapy multivariable logistic regression Necrosis objective Odds ratio outcome pandemic participant Patient Point psoriasis receipt receiving reference treatment Relevance reported reporting bias Result Rheumatic diseases rheumatoid arthritis risk Sensitivity analyses sensitivity analysis setting significantly higher Support Symptom the mean therapy TNF treatment regimen Tumor tumor necrosis tumor necrosis factor
[DOI] 10.1001/jamanetworkopen.2021.29639 PMC 바로가기 [Article Type] Research

COVID-19 infection in adult patients with hematological malignancies: a European Hematology Association Survey (EPICOVIDEHA)

혈액 악성 악성 종양이있는 성인 환자의 COVID-19 감염 : 유럽 혈액학 협회 조사 (Epicovideha)

Clinical Trial

Published on 2021-10-142022-08-13
Journal: Journal of Hematology & Oncology [Category] MERS, SARS, 임상, 진단,

[키워드] active malignancy acute myeloid leukemia Adult patients adverse outcome adverse outcomes age Analysis analyzed baseline characteristics cause of death chronic cardiac disease chronic lymphoid leukemia Clinical management Combination complications correlated COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients death died EHA EPICOVIDEHA Epidemiology European Hematology Association group hematological Hematological malignancies Hematological malignancy hematology high risk HM patient HM patients Hospitalized ICU ICUs IMPROVE include increase in intensive care unit intensive care units laboratory-confirmed Laboratory-confirmed COVID-19 leukemia Liver disease lymphoproliferative lymphoproliferative diseases malignancy Mortality mortality rate mortality risk multivariable analysis Myelodysplastic syndrome myelodysplastic syndromes Myeloma myeloproliferative malignancies myeloproliferative malignancy Non-Hodgkin Lymphoma p value Patient patients patients with HM predictor reduced renal impairment reported Result risk factor Risk factors SARS-CoV-2 disease SARS-CoV-2 disease 2019 second wave significantly smoking supplementary material supported survey the patient working
[DOI] 10.1186/s13045-021-01177-0 PMC 바로가기 [Article Type] Clinical Trial

SARS-CoV-2 viral load as a predictor for disease severity in outpatients and hospitalised patients with COVID-19: A prospective cohort study

COVID-19로 외래 환자 및 입원 환자의 질병 중증도에 대한 예측 인자로서의 SARS-CoV-2 바이러스 부하: 전향적 코호트 연구

Research Article

Published on 2021-10-122022-09-12
Journal: PLoS ONE [Category] MERS, SARS, 진단,

[키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adjusted analysis Adult patients airway Analysis association baseline Chain Reaction confidence Confidence intervals confounding factor confounding factors coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 Department disease severity higher risk Hospital admission hospitalisation hospitalised patient Hospitalised patients identify independent independent of Infectious diseases interquartile range interval Logistic regression Logistic regression analyses median non-hospitalised Odds ratio Odds ratios outcome Outpatient outpatients Patient PCR PCR positive performed polymerase chain polymerase chain reaction predict prospective cohort study quantification Registered Result SARS-CoV-2 SARS-CoV-2 PCR SARS-CoV-2 viral load severe acute respiratory syndrome Coronavirus severe disease surrogate symptom onset timing of testing Univariate analysis university Viral load were used
[DOI] 10.1371/journal.pone.0258421 PMC 바로가기 [Article Type] Research Article

Open-label randomized controlled trial of ultra-low tidal ventilation without extracorporeal circulation in patients with COVID-19 pneumonia and moderate to severe ARDS: study protocol for the VT4COVID trial

COVID-19 폐렴 및 중등도에서 중증 ARDS 환자에서 체외 순환이 없는 초저 일회 호흡 호흡의 공개 라벨 무작위 대조 시험: VT4COVID 시험을 위한 연구 프로토콜

Study Protocol

Published on 2021-10-112022-09-10
Journal: Trials [Category] MERS, SARS, 임상,

[키워드] 1:1 acute respiratory distress syndrome Adult patient Adult patients all-cause mortality Analysis analyzed ARDS block body weight circulation complication of COVID-19 consumables control group COVID-19 COVID-19 pneumonia criterion data-driven defined distress eligible extracorporeal circulation groups Inclusion intensive care intensive care unit intention-to-treat intervention group Invasive mechanical ventilation less Lung injury manuscript mechanical ventilation Mild moderate Mortality mortality rate outcomes PaO Patient patients with COVID-19 Pneumonia predicted Prevent Primary outcome Protective random randomization list Randomized Randomized controlled trial recruitment reduce respiratory distress Respiratory distress syndrome SARS-CoV-2 selective severe ARDS stratified Study protocol supplementary material syndrome Tidal volume Transparency treat Trial Trial registration Ultra-low tidal volume ventilation Ultraprotective ventilation Ventilated Ventilation ventilator ventilator-free day Ventilator-free days Volume worldwide pandemic
[DOI] 10.1186/s13063-021-05665-z PMC 바로가기 [Article Type] Study Protocol

Increased serum catalytic iron may mediate tissue injury and death in patients with COVID-19

증가 된 혈청 촉매 철분은 Covid-19 환자에서 조직 손상 및 사망을 매개 할 수 있습니다.

Article

Published on 2021-10-042022-09-10
Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 임상, 치료기술,

[키워드] 95% CI active form Adult patients adverse outcome adverse outcomes age age and gender Analysis association baseline levels Biomarkers catalytic Clinical diagnosis Composite COVID-19 cross-sectional death determine disease disease severity enrolled examined Factor ferritin ferritin level ferritin levels hepcidin in-hospital mortality Increased Infectious diseases iron iron chelation Iron metabolism joint kidney males mechanical ventilation median age metabolism Molecular biology Molecular medicine occurred outcome parameter Pathogenesis pathophysiologic pathophysiology pathway Patient patients patients hospitalized patients with COVID-19 Previous studies previous study Primary outcome Prognostic markers raising replacement therapy serum significantly therapy tissue injury Transferrin Ventilation was done
[DOI] 10.1038/s41598-021-99142-x PMC 바로가기 [Article Type] Article

Pediatric P-ANCA vasculitis following COVID-19

COVID-19에 따른 소아 P-ANCA 혈관염

Case Reports

Published on 2021-10-012022-09-11
Journal: Pediatric pulmonology [Category] MERS, SARS, 바이오마커, 진단,

Delirium in critical illness: clinical manifestations, outcomes, and management

중환자의 섬망: 임상 증상, 결과 및 관리

Review

Published on 2021-10-012022-09-11
Journal: Intensive care medicine [Category] SARS, 치료기술,

[키워드] Adult patients Agitation Antipsychotics baseline Brain Care clinical manifestations Cognitive impairment Coma Compliance COVID-19 pandemic Critical Critical care Critically ill critically ill patients death delirium Dementia Deprivation detect discharge Disruption dysfunction Dysnatremia facilitate Factors greater Hearing hygiene hypoglycemia hypothese hypotheses ICU ICU Liberation. Immobility implementation IMPROVE include information inherent Injury intensive care intensive care unit Isolation less limitation management mechanism medication medications metabolic disturbance metabolic disturbances nursing homes outcomes Patient patients precipitating factors Predictive Sedation Sepsis shown Sleep Sleep Hygiene survival uremia
[DOI] 10.1007/s00134-021-06503-1 PMC 바로가기 [Article Type] Review

Implementation of serological and molecular tools to inform COVID-19 patient management: protocol for the GENCOV prospective cohort study

COVID-19 환자 관리를 알리는 혈청학적 및 분자적 도구의 구현: GENCOV 전향적 코호트 연구를 위한 프로토콜

Article

Published on 2021-09-302022-09-11
Journal: BMJ Open [Category] SARS, 변종, 진단,

[키워드] Adult patients antibody Antibody Response antibody titres Antigen approved association B-cell baseline blood sample Blood samples Characteristics clinical Clinical data clinical trials Clinical Trials Ontario collected conducted correlated COVID-19 COVID-19 patient COVID-19 symptoms determine Diagnosis diagnostics disease severity Ethics evaluate genetic difference genetic differences genetic marker Genetic markers genetics Genome Genome sequencing genomic variant Greater Toronto Area hospitals Host host genome identify immune response immunology Infection information isotype leucocyte Lineage molecular molecular diagnostics Observational cohort study outcome outcomes participant Patient patients with COVID-19 peer-reviewed physiological response prospective cohort study protocol receiving receptor Regression regression models Research Research Ethics review SARS-COV-2 infection SARS-CoV-2 virus sequence information sequenced Sequencing serological severity severity of COVID-19 Symptom System T-cell the antibody response the SARS-CoV-2 virus Variability Viral viral genomes viral neutralisation virus genome
[DOI] 10.1136/bmjopen-2021-052842 PMC 바로가기 [Article Type] Article