Clara Cell 10 kDa Protein Alleviates Murine Hepatitis Virus Strain 3-Induced Fulminant Hepatitis by Inhibiting Fibrinogen-Like Protein 2 ExpressionImmunology Published on 2018-12-132022-11-01 Journal: Frontiers in Immunology [Category] Coronavirus, [키워드] abrogated accompanied administration allergic rhinitis ALT anti-inflammatory property Apoptosis AST Asthma CC10 Cell cells co-immunoprecipitation control group determine disease downregulated Effect examined expression Fgl2 fulminant fulminant hepatitis HBP1 Hepatitis histology Human IL-1β Immune cell in vitro Infection inhibit inhibitory effect injection innate immune responses Interaction investigated involved kDa Kupffer cells liver Liver damage Liver function Macrophage macrophages mechanism MHV-3 mice murine hepatitis virus Necrosis pathogenic peritoneal macrophage PROTECT Protein Real-time PCR Regulation Regulatory represse serum shown significantly strain suggested survival rate THP-1 TNF-α transcription factor Treatment Vein viral infection was reduced western blot [DOI] 10.3389/fimmu.2018.02935 PMC 바로가기 [Article Type] Immunology