avidity

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antibody Antibody avidity antibody COVA1-16 approach avidity bind binding block CDR CDR H3 complementarity-determining region conserved coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus vaccines COVA1-16 COVID-19 cross-neutralization activity cross-neutralize cross-neutralizing cross-reactivity crystal structure domain driven by epitope epitope conservation Fab flexible functional IgG individual individual with COVID-19 Mediated MOST negative-stain electron microscopy neutralization overlap RBD RBS receptor respiratory SARS-CoV SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 RBD SARS-like coronavirus vaccine severe acute respiratory syndrome Coronavirus Site spike glycoprotein steric hindrance Structure the RBD the SARS-CoV-2 Therapies trimer Virus neutralization X-ray
[DOI] 10.1016/j.immuni.2020.10.023 PMC 바로가기 [Article Type] Article