Effect of BCG Revaccination on Occupationally Exposed Medical Personnel Vaccinated against SARS-CoV-2SARS-CoV-2 예방 접종을 받은 직업적으로 노출된 의료진에 대한 BCG 재접종의 영향Article Published on 2021-11-152022-09-12 Journal: Cells [Category] MERS, SARS, 진단, [키워드] Administered allele anti-SARS-CoV-2 BCG both group Concentration confounding effect COVID-19 COVID-19 patients cytokine Effect exhibited Frequency genotyped GM-CSF group HLA-DRB1 IL-12p70 IL-13 IL-18 IL-1β IL-4 IL-6 individual INF-γ loci Neutralizing antibodies neutralizing antibody neutralizing antibody titers nine participant Patient Placebo protocol Randomized reducing revaccination SARS-CoV-2 serum serum cytokine severe COVID-19 specific neutralizing antibody subsequent thought TNF-α vaccination Vaccine vaccine group was determined [DOI] 10.3390/cells10113179 PMC 바로가기 [Article Type] Article
Impact of Bacillus Calmette-Guérin (BCG) vaccination on postoperative mortality in patients with perioperative SARS-CoV-2 infectionResearch Letter Published on 2021-11-082022-10-28 Journal: BJS Open [Category] COVID-19, MERS, SARS, [키워드] 30-Day mortality Bacillus Bacillus Calmette-Guérin BCG BCG vaccination Evidence Impact Mortality Patient postoperative PROTECT protective role pulmonary complication SARS-CoV-2 infected patient SARS-COV-2 infection SARS-CoV-2 vaccination vaccination [DOI] 10.1093/bjsopen/zrab131 PMC 바로가기 [Article Type] Research Letter
Effects of Bacille Calmette Guerin (BCG) vaccination during COVID-19 infectionResearch article Published on 2021-11-012022-10-05 Journal: Computers in biology and medicine [Category] SARS, 바이오마커, 변종, [키워드] activities acute respiratory syndrome ADORA3 analysed Analysis Bacille calmette guerin (BCG) BCG BCG vaccination caused CCL4 CCR2 CD33 Comorbidity condition contagious coronavirus coronavirus disease COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 patient COVID‐19 Critical CXCL1 CXCL8 cytokine DEGs differentially expressed gene Differentially expressed genes driving drug candidate Drug molecules Effect elements enrichment analysis expression expression pattern finding functional Functional enrichment analysis Gene ontology Genes Genetic IFNg IL-17 Infection Interaction investigated ITGB2 miRNA molecular mononuclear cell more difficult Mortality network analysis Novel coronavirus pandemic pathway Pathways PBMC Peripheral blood PPI PTGS2 Regulatory Research SARS-CoV-2 SARS-COV-2 infection severity significantly Spread TFS therapeutic TLR5 transcriptomic vaccination Vaccine virus spread [DOI] 10.1016/j.compbiomed.2021.104891 [Article Type] Research article
The effect of BCG revaccination on all-cause mortality beyond infancy: 30-year follow-up of a population-based, double-blind, randomised placebo-controlled trial in Malawi유아기를 넘어서 모든 원인 사망률에 대한 BCG 재검토의 효과 : 말라위에서 인구 기반, 이중 맹검, 무작위 위약 대조 시험의 30 년 추적 관찰Randomized Controlled Trial Published on 2021-11-012022-08-13 Journal: The Lancet. Infectious Diseases [Category] MERS, SARS, 비임상, 임상, 한센병, [키워드] Adults age all-cause mortality Analysis assigned BCG BCG vaccination breath cause children death deaths District double-blind Effect enrolled Evidence evidence of finding Follow-up funding Glaxo-strain In-vitro individual infancy Infant Infants information LEPRA leprosy Mortality no difference non-infectious non-specific participant per 1000 person-year Placebo placebo group placebo recipient placebo recipients placebo-controlled trial Prevent prevention proportion randomised randomised controlled Randomly receive recipient recorded reduce relief revaccination risk severity of COVID-19 Sex Surveillance survival survival analysis the District the placebo group time interval Trial Tuberculosis vaccination Wellcome Trust were recorded Year [DOI] 10.1016/S1473-3099(20)30994-4 PMC 바로가기 [Article Type] Randomized Controlled Trial
BCG vaccination and the risk of COVID 19: A possible correlationArticle Published on 2021-10-282023-06-15 Journal: Virology [Category] MERS, SARS, [키워드] Bacillus Calmette–Guérin BCG COVID-19 Gene Expression macrophages Monocytes SARS-CoV2 [DOI] 10.1016/j.virol.2021.10.003 PMC 바로가기 [Article Type] Article
BCG vaccination to reduce the impact of COVID-19 in healthcare workers: Protocol for a randomised controlled trial (BRACE trial)의료 종사자에서 Covid-19의 영향을 줄이기위한 BCG 예방 접종 : 무작위 대조 시험을위한 프로토콜 (Brace Trial)Infectious Diseases Published on 2021-10-272022-09-10 Journal: BMJ Open [Category] Fulltext, MERS, SARS, 임상, [키워드] 1:1 Analysis approval BCG BCG vaccination Blood Blood samples Brazil changes in ClinicalTrials collected control group Controlled trial COVID-19 database determine dissemination episode of Ethics evaluated Factor febrile Final group HCW HCWs healthcare healthcare worker Healthcare workers identify immune response immune responses immune system Immunological analyses immunology incidence infections Infectious diseases International Intervention Microbiology modulate multicentre Netherlands outcomes participant Pathogens peer-reviewed questionnaire Questionnaires randomised controlled trial reduce Repository respiratory Respiratory illness Result safety profile SARS-CoV-2 SARS-COV-2 infection Secondary objectives severe COVID-19 severity Spain susceptibility symptomatic tested Trial Trial registration vaccination Virology [DOI] 10.1136/bmjopen-2021-052101 PMC 바로가기 [Article Type] Infectious Diseases
The Determinants of the Low COVID-19 Transmission and Mortality Rates in Africa: A Cross-Country Analysis아프리카의 낮은 COVID-19 전파 및 사망률의 결정 요인: 국가 간 분석Public Health Published on 2021-10-212022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 치료기술, [키워드] adjusted Africa African Analysis array association Bacillus BCG BMI body mass body mass index categories collected collinearity communicable communicable disease continent coronavirus Coronavirus 2019 country covariate covariates Coverage COVID-19 COVID-19 case COVID-19 cases COVID-19 pandemic COVID-19 test COVID-19 tests cross-country analysis cumulative death detect determinant diabete diabetes disease epidemiological Factor focus GHS global health security health system help index International investigated Life expectancy media Mortality mortality rate mortality rates multiple regression model Nurses observation parameters Pollution predictor Prevalence proportion public health Radiation Rate reported respiratory respiratory infection respiratory infections respond rural population selected significantly social media Spread statistical the median Transmission variable variables variance inflation factor VIF were used with COVID-19 [DOI] 10.3389/fpubh.2021.751197 PMC 바로가기 [Article Type] Public Health
The Impact of SARS-CoV-2 Pandemic on Time to Primary, Secondary Resection and Adjuvant Intravesical Therapy in Patients with High-Risk Non-Muscle Invasive Bladder Cancer: A Retrospective Multi-Institutional Cohort AnalysisArticle Published on 2021-10-212022-10-31 Journal: Cancers [Category] COVID-19, [키워드] adjuvant assist BCG Bladder cancer conditions COVID-19 COVID-19 emergency COVID-19 outbreak COVID-19 pandemic database Diagnosis disease distribution health system Healthcare system Impact infected patient intravesical Intravesical BCG invasive investigation Italian Italy malignancy management median time pandemic Patient patients proportion Re-TURBT recorded Resection Retrospective analysis Retrospective study SARS-CoV-2 secondary significant delay significant difference significantly simple surgical survival survivor the patient therapeutic therapy time trans-urethral resection of bladder tumor treat Treatment two group was performed [DOI] 10.3390/cancers13215276 PMC 바로가기 [Article Type] Article
COVID-19 and Beyond: Exploring Public Health Benefits from Non-Specific Effects of BCG VaccinationReview Published on 2021-10-092022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] Bacille Calmette–Guérin BCG BCG vaccination complicate COVID-19 COVID-19 pandemic disease severity Effect Effectiveness groups Health Benefit Healthcare system illnesses immune Infection interest mechanism Meningitis miliary tuberculosis Mortality Mycobacterium tuberculosis National non-specific overcome PROTECT Public public health public health policy reactivity reduce Respiratory disease respiratory infection risk Scientific community Spread the United State The United States tuberculin skin test tuberculous vaccination Vaccine [DOI] 10.3390/microorganisms9102120 PMC 바로가기 [Article Type] Review
100 years of Bacillus Calmette-Guérin immunotherapy: from cattle to COVID-19Bacillus Calmette-Guérin 면역 요법의 100년: 소에서 COVID-19까지Review Published on 2021-10-012022-09-12 Journal: Nature reviews. Urology [Category] MERS, 유전자 메커니즘, 임상, 진단, 치료법, [키워드] Bacillus BCG BCG vaccination Bladder cancer coronavirus disease COVID-19 COVID-19 pandemic Effect Evidence highlight Hypothesis immune response Immunity indicate non-specific occur offer Prevent PROTECT severity stimulate Treatment Tuberculosis Vaccine viral infections [DOI] 10.1038/s41585-021-00481-1 PMC 바로가기 [Article Type] Review