Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27Article Published on 2015-08-182022-10-29 Journal: Scientific Reports [Category] Coronavirus, [키워드] Analysis antibody assist binding binding site biochemical carbohydrate cause Critical DPP4 epitope Fab fragment Human Human monoclonal antibody inhibit interact Interaction membrane fusion MERS-CoV MERS-CoV infection MERS-CoV RBD Middle East molecular basis mortality rate neutralization neutralization activity overlap RBD receptor Receptor binding Receptor binding domain reported residue residues respiratory syndrome coronavirus severe respiratory illness spike glycoprotein the RBD viral entry [DOI] 10.1038/srep13133 PMC 바로가기 [Article Type] Article
Targeting N-Glycan Cryptic Sugar Moieties for Broad-Spectrum Virus Neutralization: Progress in Identifying Conserved Molecular Targets in Viruses of Distinct Phylogenetic OriginsArticle Published on 2015-03-122022-10-30 Journal: Molecules [Category] Coronavirus, [키워드] 2G12 activities activity acute respiratory syndrome AGOR analyses Antigen antigens ASOR carbohydrate carbohydrate microarrays characterized conserved coronavirus epitope Epitopes Express Galanthus genomic GlcNAc glycan glycosylation GNA HCMV high-density highlight HIV-1 Host Human Cytomegalovirus Human monoclonal antibody identifying include information Man Microarray moiety molecular basis molecular target neutralize oligomannoses origin Phylogenetic probes profile Progress Protein target reactive recognize SARS-CoV sugar moieties sugar moiety target targeting Vaccine viral pathogens virus Virus neutralization virus-neutralizing virus-neutralizing antibody [DOI] 10.3390/molecules20034610 PMC 바로가기 [Article Type] Article
Conformational Analysis of the Streptococcus pneumoniae Hyaluronate Lyase and Characterization of Its Hyaluronan-specific Carbohydrate-binding Module *스트렙토코쿠스 뉴모니아 하이알루론산 리아제의 구조적 분석 및 하이알루로난 특이적 탄수화물 결합 모듈의 특성화 *Article Published on 2014-09-262024-08-04 Journal: Brain stimulation [Category] 폐렴구균 감염증, [키워드] carbohydrate Carbohydrate Processing carbohydrate-binding protein Crystallography glycobiology Hyaluronan Hyaluronate Lyase Small Angle X-ray Scattering (SAXS) Streptococcus [DOI] 10.1074/jbc.M114.578435 PMC 바로가기