Chemical – Page 6 – Communicable Diseases Research

Assessment of dispersion of airborne particles of oral/nasal fluid by high flow nasal cannula therapy

고유량 비강 캐뉼라 요법에 의한 구강/비강액의 공기 중 입자 분산 평가

Research Article

Published on 2021-02-122022-08-13
Journal: PLoS ONE [Category] MERS, 임상,

A double blinded placebo controlled comparative clinical trial to evaluate the effectiveness of Siddha medicines, Kaba Sura Kudineer (KSK) & Nilavembu Kudineer (NVK) along with standard Allopathy treatment in the management of symptomatic COVID 19 patients – a structured summary of a study protocol for a randomized controlled trial

증상이 있는 COVID 19 환자의 관리에서 표준 동종 요법 치료와 함께 Siddha 의약품, Kaba Sura Kudineer(KSK) 및 Nilavembu Kudineer(NVK)의 효과를 평가하기 위한 이중 맹검 위약 대조 비교 임상 시험 - 에 대한 연구 프로토콜의 구조화된 요약 무작위 대조 시험

Letter

Published on 2021-02-112022-09-10
Journal: Trials [Category] MERS, 임상,

[키워드] acute respiratory distress syndrome addition Adverse adverse events age age and sex appearance Arm Asymptomatic Bacterial biochemical markers blinded block calculated CAM change Chemical clinical clinical symptom Clinical symptoms clinical trial Complication complications Controlled count COVID COVID 19 COVID 19 patient CRP Ct value CTRI D-dimer Data analysis Date determine diagnose dimer dissemination drug Effect Effectiveness element eligibility eliminated enrolment evaluate exploratory ferritin food GMP group Herbal Hospital stay IL 6 IL6 incidence India Infection infiltration Inflammatory marker inflammatory markers Informed consent investigators involved Laboratory LDH literature management marker Medical Sciences Medicine Medicines Microsoft Excel moderate symptom moderate symptoms morning Night number objective outcome participant Patient patients PCR Placebo Pneumonia profile protocol randomised controlled trial randomization Randomized Randomized controlled trial Ratio recruited recruitment reduce reduction Registered Registration registry reported respiratory respiratory distress Respiratory distress syndrome risk Sample Sample size SARS-CoV-2 secondary Secondary objectives Secondary outcomes severe COVID-19 symptoms Siddha Siddha Medicine smoking SPIRIT guidelines statistician status Study protocol submission Sura symptomatic Taste tea the disease time Total Treatment Trial trial protocol Trial registration value Viral Viral load Viral pneumonia website were blinded
[DOI] 10.1186/s13063-021-05041-x PMC 바로가기 [Article Type] Letter

Analysis of the Chemical and Physical Environmental Aspects that Promoted the Spread of SARS-CoV-2 in the Lombard Area

Article

Published on 2021-01-292022-10-29
Journal: International Journal of Environmental Research an [Category] COVID-19, MERS,

A Ligand Selection Strategy Identifies Chemical Probes Targeting the Proteases of SARS‐CoV‐2

Research Article

Published on 2021-01-282022-10-28
Journal: Angewandte Chemie (International ed. in English) [Category] COVID-19, SARS,

[키워드] 3CL pro ABPP approach Cell Chemical chemical probes complementary cysteine protease derivative develop Efficacy electrophilic enzyme Enzyme inhibitors inhibitor inhibitors labeling Ligand probe protease Proteases proteome proteomic resulting SARS‐CoV‐2 Selection specificity Strategy target protein targeting tuning virus
[DOI] 10.1002/anie.202016113 PMC 바로가기 [Article Type] Research Article

Chemical profiling of selected Ayurveda formulations recommended for COVID-19

Research

Published on 2021-01-112022-10-28
Journal: Beni-Suef University Journal of Basic and Applied Sciences [Category] COVID-19,

An efficient chemical screening method for structure-based inhibitors to nucleic acid enzymes targeting the DNA repair-replication interface and SARS CoV-2

DNA 복구-복제 인터페이스 및 SARS CoV-2를 표적으로 하는 핵산 효소에 대한 구조 기반 억제제에 대한 효율적인 화학적 스크리닝 방법

Article

Published on 2021-01-012022-09-11
Journal: Molecules [Category] Coronavirus, 유전자 메커니즘,

[키워드] Absorption ADME ADP-ribose affinity approach approved Cancer cancer cell Cancer cells Cassandra CASSIE Cell Chemical Chemical library Chemistry classical Compound defined distribution DNA DNA replication DNA replication and repair docking drug drug design Drug discovery effective effort enzyme excretion facilitate human protein human proteins increasingly inhibitor inhibitors iterative Mac1 macrodomain mechanism metabolism molecular nonstructural protein 3 Nsp3 nucleic acid optimization PARG Pathogenesis pathway predicted problem profiles protein 3 Proteins provide repair ribose RNA SARS CoV SARS CoV-2 SARS-CoV2 Screen screening method specific inhibitor specific inhibitors Structure structures target to define
[DOI] 10.1016/bs.mie.2021.09.003 PMC 바로가기 [Article Type] Article

Chemical Translational Biology-Guided Molecular Diagnostics: The Front Line To Mediate the Current SARS-CoV-2 Pandemic

화학 번역 생물학 유도 분자 진단: 현재 SARS-CoV-2 유행병을 중재하는 최전선

Article

Published on 2020-12-112022-09-12
Journal: Chembiochem [Category] MERS, SARS, 진단,

A ligand-based computational drug repurposing pipeline using KNIME and Programmatic Data Access: case studies for rare diseases and COVID-19

Educational

Published on 2020-11-252022-10-31
Journal: Journal of Cheminformatics [Category] COVID-19,

An Overview on SARS-CoV-2 (COVID-19) and Other Human Coronaviruses and Their Detection Capability via Amplification Assay, Chemical Sensing, Biosensing, Immunosensing, and Clinical Assays

Review

Published on 2020-11-022022-10-30
Journal: Nano-Micro Letters [Category] COVID-19,

Potential of Cell-Free Supernatant from Lactobacillus plantarum NIBR97, Including Novel Bacteriocins, as a Natural Alternative to Chemical Disinfectants

Article

Published on 2020-09-232022-10-28
Journal: Pharmaceuticals [Category] COVID-19,