Multiple system inflammatory syndrome associated with SARS-CoV-2 infection in an adult and an adolescent성인 및 청소년의 SARS-CoV-2 감염과 관련된 다계통 염증 증후군Case Reports Published on 2021-05-012022-09-12 Journal: Rheumatology International [Category] SARS, 진단, [키워드] abnormality age analyzed article cardiovascular Clinical finding Clinical improvement conjunctival COVID-19 criteria database described Diagnosis effective implementation Inflammatory Inflammatory biomarker Intervention Intravenous immunoglobulin IVIG Laboratory MIS MIS-A MOST Multiple Multisystem inflammatory syndrome Patient patients predominant pulse Pulse steroid. reported respiratory symptom risk SARS-COV-2 infection searched steroid treatment suggested supportive care Symptoms syndrome the patient treated Treatment was performed Web of Science with COVID-19 [DOI] 10.1007/s00296-021-04843-1 PMC 바로가기 [Article Type] Case Reports
Obesity as a Risk Factor for Severe COVID-19 and Complications: A ReviewReview Published on 2021-04-172022-10-31 Journal: Cells [Category] COVID-19, MERS, SARS, [키워드] ACE2 acute respiratory distress angiotensin-converting enzyme 2 ARDS Blood coagulation chronic inflammation Clinical finding Coagulopathy Complication complications consequence contribute COVID-19 COVID-19 disease severity Cytokine storm disease severity elevated explain facilitated Factor feature ferritin level hemorrhage hyper-inflammatory response impaired viral clearance Inflammation insulin Leptin mechanism obesity Patient potential mechanism Prevalence preventive measure progression receptors review risk risk factor SARS-CoV-2 SARS-COV-2 infection second severe COVID-19 Signaling syndrome therapeutic intervention thrombus formation understanding upregulation viral entry [DOI] 10.3390/cells10040933 PMC 바로가기 [Article Type] Review
Letter to the editor: Vitamin D levels in acute illness and clinical severity in COVID-19 patientsLetter to the Editor Published on 2021-04-092022-10-28 Journal: Respiratory Research [Category] Coronavirus, MERS, SARS, [키워드] 25-hydroxyvitamin D acute illness Admission association CD4/CD8 Clinical finding Clinical severity COVID-19 COVID-19 patient COVID-19 patients Critical D-dimer debatable disease severity elevated hospital IL-6 levels Inflammation initial intensive care interleukin-6 LIPI mechanical ventilation Mortality predict prognostic reported SARS-CoV-2 SOFA SOFA score SOFA scores symptom onset the patient two group Vitamin D vitamin D level [DOI] 10.1186/s12931-021-01703-1 PMC 바로가기 [Article Type] Letter to the Editor
Repurposing of some anti-infective drugs for COVID-19 treatment: A surveillance study supported by an in silico investigationCOVID-19 치료를 위한 일부 항감염제의 용도 변경: in silico 조사에 의해 뒷받침되는 감시 연구Article Published on 2021-04-012022-09-11 Journal: International journal of clinical practice [Category] SARS, 신약개발, 치료기술, 치료제, [키워드] AAK1 added Admission ADP-ribose anti-infective drug antimicrobial Antimicrobials applied Azithromycin binding binding free energy binding mode binding modes Clinical finding Clinical findings clinical outcomes Combination Compound computational studies Computational study COVID-19 death detect diarrhoea docked docking experiment docking experiments docking score doxycycline drug effective Efficacy enrolled explain females four groups free energy Free energy calculations group IMPROVE in silico in vitro inhibitors intensive care kinase lead MDs Mild mild to moderate moderate Moderate COVID-19 moderate symptoms molecular molecular dynamic simulations nitazoxanide not seen outcomes phosphatase Protein target replacement reported repurposing required Reverse transcription-polymerase chain reaction ribose starting point subject subjects supported Surveillance Symptom symptomatic improvement therapeutic potential treated treating COVID-19 Treatment turn Viral [DOI] 10.1111/ijcp.13877 PMC 바로가기 [Article Type] Article
COVID-19-Associated Suspected Myocarditis as the Etiology for Recurrent and Protracted Fever in an Otherwise Healthy Adult건강한 성인의 재발성 및 지속성 발열의 병인으로서의 COVID-19 관련 심근염 의심Review Published on 2021-04-012022-09-11 Journal: The American journal of the medical sciences [Category] MERS, SARS, 바이오마커, [키워드] Acute myocarditis Admission cardiovascular complications Clinical finding concerning COVID-19 current diagnosis of COVID-19 disease Fever followed by healthy initial Laboratory male myocardial injury myocarditis novel corona virus presenting Recurrent SARS-CoV-2 Suspected Troponin-I Viral Viral cardiovascular complications. Virus Disease [DOI] 10.1016/j.amjms.2020.11.001 PMC 바로가기 [Article Type] Review
Subacute cerebellar ataxia following respiratory symptoms of COVID-19: a case reportCase Report Published on 2021-03-242022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, [키워드] absence acute respiratory syndrome Anosmia/ageusia antibody production assumed Ataxia Atypical Autoimmune Case report cause cell count cerebral cerebrospinal fluid Clinical finding clinician Coronavirus disease 2019 corticosteroid treatment COVID-19 described disease Dizziness excluded fatigue Fever headache High-dose high-dose methylprednisolone Immune-mediated Laboratory less magnetic resonance imaging mechanism Mild Miller fisher syndrome neurological Neurological deficit Neurological symptom occur Other Post-infectious cerebellar ataxia Post-infectious neurological disease respiratory symptom respiratory symptoms SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA Seizures Subacute symptomatic SARS-CoV-2 infection syndrome therapy upper airways viral infections virus [DOI] 10.1186/s12879-021-05987-y PMC 바로가기 [Article Type] Case Report
Undetected Causes of Death in Hospitalized Elderly with COVID-19: Lessons from AutopsyArticle Published on 2021-03-242022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] alveolar damage Autopsy cardiovascular disease Care cause causes Clinical finding Comorbidities Comorbidity Complication complications conducted contributed coronavirus disease correlation COVID-19 death diagnose Diagnosis died elderly elderly patients FIVE heart failure Hospitalized hypertension hypoxemic lesson median median age Mortality occurred Older older patient Organizing pneumonia Pathological examination Patient patients died performed positive Post-mortem proliferative Respiratory failure retrospective SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pneumonia [DOI] 10.3390/jcm10071337 PMC 바로가기 [Article Type] Article
Impact of COVID-19 outbreak on hospital admissions and outcome of acute coronary syndromes in a single high-volume centre in southeastern EuropeOriginal Article Published on 2021-03-112022-10-30 Journal: Netherlands Heart Journal [Category] COVID-19, [키워드] 95% confidence interval Acute coronary syndrome Acute heart failure Admission affected analysed changes in Clinical finding Complication coronary syndrome coronavirus disease country COVID-19 COVID-19 outbreak Europe Frame healthcare services Hospital admission hospitalisation Impact in-hospital mortality increases in morbidity and mortality Mortality mortality rate Myocardial infarction outcome pandemic status parameter Patient patients reached reduced reduction reported Result retrospective subgroup of patients Treatment [DOI] 10.1007/s12471-021-01554-x PMC 바로가기 [Article Type] Original Article
The Centrality of Obesity in the Course of Severe COVID-19Endocrinology Published on 2021-03-112022-10-31 Journal: Frontiers in Endocrinology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory distress acute respiratory syndrome advanced age ARDS cardiovascular disease cascade caused Chronic diseases Chronic kidney disease CKD Clinical finding coronavirus coronavirus disease Course COVID-19 COVID-19 patients CVD Diabetes Mellitus disorder disorders global public health Health hypertension increase individual initiate investigated mechanism Mortality mortality rate Most patient obesity obesity-associated comorbidities pandemic pathophysiology Patient progression risk factor SARS-CoV-2 severe complication severe complications severity of COVID-19 smoking Support susceptibility syndrome Therapeutic strategies therapy [DOI] 10.3389/fendo.2021.620566 PMC 바로가기 [Article Type] Endocrinology
Epidemiological and clinical features in patients with coronavirus disease 2019 outside of Wuhan, China: Special focus in asymptomatic patientsResearch Article Published on 2021-03-102022-10-28 Journal: PLoS Neglected Tropical Diseases [Category] COVID-19, SARS, [키워드] addition affected Asymptomatic asymptomatic patient asymptomatic patients case sery characteristic Characteristics characteristics of patient city Clinical characteristics clinical feature Clinical finding Cluster Contact coronavirus disease cough COVID-19 demographic characteristics disease onset Epidemic epidemiological Fever identify Incubation period Infection initial Laboratory laboratory-confirmed SARS-CoV-2 infection median Mild objective Patient patients with COVID-19 pneumonia cases Population Region reported Result SARS-COV-2 infection Spread Symptom the disease the patient Treatment upper respiratory tract URTI Viral pneumonia were assessed Wuhan [DOI] 10.1371/journal.pntd.0009248 PMC 바로가기 [Article Type] Research Article