Prognostic performance of troponin in COVID-19: A diagnostic meta-analysis and meta-regressionCOVID-19에서 트로포닌의 예후 성능: 진단 메타 분석 및 메타 회귀Meta-Analysis Published on 2021-04-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 바이오마커, 진단, [키워드] 95% confidence interval affecting age association cardiac cardiac injury Coronary artery Coronary artery disease coronavirus disease Coronavirus disease 2019 COVID-19 database databases defined diabete diabetes Diagnosis diagnostic elevated Factor Gender heart hypertension inception increased mortality increased risk likelihood ratio male Meta-analysis meta-regression Mortality mortality rate myocardial damage Odds ratio outcome Patient patients patients with COVID-19 positive Predictive Probability Prognosis Prognostic value sensitivity serum troponin specificity systematic review troponin upper reference limit [DOI] 10.1016/j.ijid.2021.02.113 PMC 바로가기 [Article Type] Meta-Analysis
Kawasaki Disease Shock Syndrome in Japan and Comparison With Multisystem Inflammatory Syndrome in Children in European countriesPediatrics Published on 2021-03-192022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] abnormality acute respiratory syndrome agonist Asia Characteristics children clinical feature Clinical sign Clinical symptoms collected data Complete Coronary artery coronavirus Diagnosis disease entity European country greater identify incidence Inflammatory Japan Kawasaki disease MIS-C Mortality multi inflammatory syndrome-children overlap Patient phenotype presenting Prognosis SARS-CoV-2 Shock similarity suggested Symptoms syndrome treated Treatment unlikely Vasoactive [DOI] 10.3389/fped.2021.625456 PMC 바로가기 [Article Type] Pediatrics
Defining Kawasaki disease and pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection during SARS-CoV-2 epidemic in Italy: results from a national, multicenter survey이탈리아에서 SARS-CoV-2 유행 중 SARS-CoV-2 감염과 일시적으로 연관된 가와사키병 및 소아 염증성 다계 증후군 정의: 국가, 다기관 설문조사 결과Observational Study Published on 2021-03-162022-09-01 Journal: Pediatric Rheumatology Online Journal [Category] SARS, 임상, 진단, [키워드] abnormality Acetylsalicylic acid age cardiac Cardiogenic shock characterized Chi square Chi square test Child child health children Clinical characteristics clinical feature Clinical features clinical manifestation clinical manifestations Cohort collected Complication complications Coronary artery Coronary artery abnormalities CRP levels database deaths demographic determine diagnosed disease elevated enrolled Evidence exact Fisher test ferritin Florence glucocorticoid Glucocorticoids group hospital Hypotension ICU admission Immunoglobulin immunoglobulins Inflammatory inflammatory disease Inflammatory diseases information IRCCS Italian IVIG Kawasaki disease laboratory data lymphopenia Mann-Whitney test Maternal multicenter Multisystem inflammatory syndrome associated with coronavirus disease myocarditis National no statistical difference Occurrence Older Older age outcome Patient patients pediatric Pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection PIMS positive relationship respiratory response to treatment Result risk SARS-CoV-2 SARS-CoV-2 epidemic SARS-COV-2 infection Shock significantly similarities similarity Society supplementary material syndrome Treatment Treatment response Trieste troponin Troponin-T two groups were used [DOI] 10.1186/s12969-021-00511-7 PMC 바로가기 [Article Type] Observational Study
Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19중증 급성 COVID-19와 비교한 어린이의 다기관 염증 증후군(MIS-C)이 있는 미국 어린이 및 청소년의 특성 및 결과Comparative Study Published on 2021-03-162022-09-11 Journal: JAMA [Category] 바이오마커, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted Adolescent Aneurysm Antibody test antibody test result antibody test results aRR black C-reactive protein cardiorespiratory Case series case sery Chain Reaction children Clinical characteristics clinical outcomes complications Coronary artery coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 criteria diagnosed Diagnosis died effort Factor female Fever Follow-up Health help hospital Hospitalization Hospitalized IMPROVE Inflammation Inflammatory intensive care intensive care unit laboratory biomarkers lymphocyte median median age MIS-C Multivariable regression neutrophil normalized organ organ system outcome outcomes Patient patients with COVID-19 PCR test Platelet Platelet count positive positive RT-PCR presenting symptoms reduced refinement respiratory reverse transcriptase reverse transcriptase-polymerase chain reaction risk risk difference risk ratio RT-PCR SARS-CoV-2 setting severe coronavirus disease Symptoms syndrome test results ventricular was used white with COVID-19 [DOI] 10.1001/jama.2021.2091 PMC 바로가기 [Article Type] Comparative Study
Cardiometabolic risk factors for COVID-19 susceptibility and severity: A Mendelian randomization analysisCOVID-19 감수성 및 중증도에 대한 심혈관 대사 위험 요소: 멘델식 무작위 분석Research Article Published on 2021-03-042022-08-13 Journal: PLoS Medicine [Category] meta-analysis, SARS, 변종, 유전자 메커니즘, 진단, 치료제, [키워드] Aaron amplified amplify analyses Analysis association associations average BMI body mass body mass index calculated cardiometabolic cardiometabolic condition cardiometabolic conditions cardiometabolic consequence cardiometabolic disease cardiometabolic diseases cardiometabolic exposure cardiometabolic risk factor Cardiometabolic risk factors cardiometabolic trait cardiometabolic traits causal relationship Causality Chronic kidney disease cohorts Conditioning Control controls Coronary artery Coronary artery disease Coronary heart disease correlated COVID-10 COVID-19 COVID-19 disease COVID-19 hospitalization COVID-19 Host Genetics Initiative GWAS meta-analyses COVID-19 illness COVID-19 pandemic COVID-19 severity COVID-19 susceptibility defined described diabetes Effect estimate European evaluate Evidence General population Genetic genetic evidence genetic instrument Genetic variant genetic variants Genome-wide association studies Genome-wide association study GWAS meta-analysis GWASs higher risk hospital Hospitalization hospitalized COVID-19 indirect effect indirect effects individual initiative Intervention Kidney disease mediators mendelian randomization Mendelian randomization analyses Mendelian randomization analysis obesity Obesity-related cardiometabolic diseases Odds ratio on type outcome outcomes p < 0.05/34 tests pairwise multivariable MR performed Pleiotropy population-based cohort population-based cohorts positive raise raising reduce repeated researcher risk risk factor Risk factors risk of COVID-19 selected severe COVID-19 severity statistical significance statistically significant stroke Support susceptibility tested traits type 2 diabetes UK biobank with COVID-19 [DOI] 10.1371/journal.pmed.1003553 PMC 바로가기 [Article Type] Research Article
Association of serum HDL-cholesterol and apolipoprotein A1 levels with risk of severe SARS-CoV-2 infection심각한 SARS-CoV-2 감염 위험과 혈청 HDL-콜레스테롤 및 아포지단백 A1 수치의 연관성Multicenter Study Published on 2021-03-022022-09-10 Journal: Journal of Lipid Research [Category] 바이오마커, 변종, [키워드] 95% CI, 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age allele alleles ApoA1, apolipoprotein A1 APOE4 apolipoprotein A1 association Biomarker CAD, coronary artery disease cholesterol clinical risk factor Clinical risk factors Coronary artery Coronary artery disease coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19, Coronavirus disease 2019 cumulative cumulative effects diabetes Effect elevated evaluated Evidence feature genetic risk score Genetic variant genetic variants GRS, genetic risk scores HDL-cholesterol higher risk homozygous hypertension ICD-10, International Classification of Diseases, Tenth Revision increase in individual Infection investigated Logistic regression analyses Logistic regression analysis mendelian randomization Mendelian randomization analyses Mendelian randomization analysis metabolic syndrome Mortality MR, Mendelian randomization MVMR, multivariate MR negative controls Novel coronavirus obesity OR, odds ratio outcomes PC, principal component reduced risk respiratory Respiratory disease risk SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 serum serum biomarker serum biomarkers severe acute respiratory syndrome Coronavirus Severe COVID-19 Infection severe respiratory disease severe SARS-CoV-2 severity of COVID-19 Sex susceptible syndrome type 2 diabetes UK biobank were used [DOI] 10.1016/j.jlr.2021.100061 PMC 바로가기 [Article Type] Multicenter Study
The effect of hepatic steatosis on COVID-19 severity: Chest computed tomography findings간 지방증이 COVID-19 중증도에 미치는 영향: 흉부 컴퓨터 단층 촬영 결과Article Published on 2021-03-012022-09-11 Journal: Saudi journal of gastroenterology : official journ [Category] SARS, 치료기술, [키워드] 95% CI 95% confidence interval age Analysis analyzed calculated Chest computed tomography Chest CT Chest CT image Chest CT images Chronic kidney disease chronic obstructive chronic obstructive pulmonary disease Clinical course Comorbidities Comorbidity Computed tomography Coronary artery Coronary artery disease COVID-19 COVID-19 patients COVID-19 severity cut-off value diabetes Diabetes Mellitus disease evaluated extension Fatty liver fatty liver disease Gender genders hepatic steatosis hypertension ICU ICU treatment identify independent independent risk factor Infection initial intensive care intensive care unit investigated involved Kidney disease laterality lesions liver lobes location Logistic regression analysis male multivariate logistic regression multivariate logistic regression analysis NAFLD Nasopharyngeal swab no significant difference Non-alcoholic fatty liver disease obstructive pulmonary disease Odds ratio Patient patients predictor Prevalence pulmonary disease required severe COVID-19 severe disease severity significantly lower spleen steatosis the disease the patient were measured were used [DOI] 10.4103/sjg.sjg_540_20 PMC 바로가기 [Article Type] Article
Clinical analysis of chronic active EBV infection with coronary artery dilatation and a matched case–control studyResearch Published on 2021-01-282024-09-02 Journal: Orphanet Journal of Rare Diseases [Category] 대상포진, [키워드] Clinical characteristics Coronary artery Epstein–Barr virus Pathogenesis [DOI] 10.1186/s13023-021-01689-5 PMC 바로가기 [Article Type] Research
Radiological Thoracic Vertebral Fractures are Highly Prevalent in COVID-19 and Predict Disease Outcomes방사선학적 흉추 골절은 COVID-19에서 매우 만연하고 질병 결과를 예측합니다Article Published on 2021-01-232022-09-11 Journal: The Journal of Clinical Endocrinology and Metaboli [Category] 치료기술, [키워드] affected bone metabolism cardiorespiratory Care Chest chest X-rays Clinical characteristics clinical impact Context Coronary artery Coronary artery disease COVID-19 COVID-19 patient COVID-19 patients disease emergency department Fracture fractures fragility Health Health care hospital Hospitalized hypertension investigated Italy marker mechanical ventilation metabolism Mild moderate Mortality noninvasive Older Osteoporosis outcomes Patient patients performed poor prognosis Prevalence reported required retrospective cohort study risk of COVID-19 San Raffaele Hospital SARS-CoV-2 Thoracic Vertebral vertebral fractures. [DOI] 10.1210/clinem/dgaa738 PMC 바로가기 [Article Type] Article
Numbers and phenotype of non-classical CD14dimCD16+ monocytes are predictors of adverse clinical outcome in patients with coronary artery disease and severe SARS-CoV-2 infection비고전적 CD14dimCD16+ 단핵구의 수와 표현형은 관상동맥 질환 및 중증 SARS-CoV-2 감염 환자에서 불리한 임상 결과의 예측인자입니다Article Published on 2021-01-012022-08-31 Journal: Cardiovascular Research [Category] 바이오마커, 진단, [키워드] acute SARS-CoV-2 infection adhesion Admission assessment Blood blood sampling CAD CD14 CD80 classical monocytes clinical assessment Clinical outcome Cohort Complication consecutive patient Coronary artery Coronary artery disease CX3CR1 Decreased decreased expression defined echocardiography Electrocardiography Endpoint Follow-up healthy control healthy controls help HLA-DR identify immune response Immuno-response index Infection infections Kaplan-Meier Kaplan-Meier curve Kaplan-Meier curves life-threatening log-rank Lung injury marker mechanical ventilation median Migration monocyte Monocytes non-classical monocyte Non-classical monocytes number Occurrence participant Patient Peripheral blood phenotype Phenotypes predictor prognostic progressive respiratory failure prospectively studied reached respiratory Respiratory failure risk risk assessments SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 patient SARS-CoV-2 patients severe SARS-CoV-2 significantly more stratified subsequent T-cell activation the median [DOI] 10.1093/cvr/cvaa328 PMC 바로가기 [Article Type] Article