coronavirus vaccine – Page 6 – Communicable Diseases Research

COVID-19 Coronavirus Vaccine Design Using Reverse Vaccinology and Machine Learning

역백신학 및 기계 학습을 사용한 COVID-19 코로나바이러스 백신 설계

Immunology

Published on 2020-07-032022-09-11
Journal: Frontiers in Immunology
[Category] MERS, SARS, 비임상,

[키워드] adhesins Analysis antigenicity applied breath Candidates caused clinical trial complementary Complete conserved contagious contagious disease coronavirus coronavirus coronavirus vaccine COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccine development develop disease effective Epitopes FIVE Host human coronavirus immune responses induce infecting Invasion lack linear B-cell epitope linear B-cell epitopes machine learning membrane MERS MERS-CoV MHC-I MHC-II mild symptoms N protein non-structural protein non-structural protein 3 non-structural proteins NSP Nsp3 NSP8 nucleocapsid predict predicted Protective Protein Proteins proteome reverse vaccinology S protein Safe SARS-CoV SARS-CoV-2 SARS-CoV-2 coronavirus sequence stimulate structural protein T-cell epitopes target tested the S protein the SARS-CoV-2 Vaccine vaccine candidate Vaccine development vaxign vaxign-ML Viral virus was selected
[DOI] 10.3389/fimmu.2020.01581 PMC 바로가기 [Article Type] Immunology

Universal coronavirus vaccines: the time to start is now

Comment

Published on 2020-05-282022-10-30
Journal: NPJ Vaccines
[Category] COVID-19,

Certainty of success: three critical parameters in coronavirus vaccine development

Review Article

Published on 2020-05-252022-10-30
Journal: NPJ Vaccines
[Category] COVID-19,

Coronavirus Non-Structural Protein 1 Is a Major Pathogenicity Factor: Implications for the Rational Design of Coronavirus Vaccines

Research Article

Published on 2007-08-102022-10-29
Journal: PLoS Pathogens
[Category] Coronavirus,

[키워드] acute respiratory syndrome analyzed antigen-presenting cell Author Cell culture Cell-mediated immunity cellular Cellular immune response coding sequence coronavirus Coronavirus infection coronavirus vaccine Coronavirus vaccines Coronaviruses Culture deleting dendritic cell disease elicited Factors Gene Expression genetics Heterologous homolog homologous IFN immune responses implication in vitro in vivo interfere long-lasting low dose macrophages Major MHV mice mouse hepatitis virus murine model mutant mutant virus non-structural protein pathogenicity plasmacytoid dendritic cells prevention Protective protective immune response Protein provide recombinant vaccine reduced replicate Replication replication-competent virus restored retained SARS-coronavirus sequence Spread T cell response tissue Type I IFN type I interferon vaccination Vaccine viral disease viral pathogenicity viral pathogens virus wild-type
[DOI] 10.1371/journal.ppat.0030109 PMC 바로가기 [Article Type] Research Article