Cutoff – Page 6 – Communicable Diseases Research

Patient Outcomes and Lessons Learned From Treating Patients With Severe COVID-19 at a Long-term Acute Care Hospital: Single-Center Retrospective Study

Original Paper

Published on 2022-02-102022-10-30
Journal: JMIR Rehabilitation and Assistive Technologies [Category] COVID-19,

Immunogenicity and Safety of the BNT162b2 mRNA COVID-19 Vaccine Among Actively Treated Cancer Patients

적극적으로 치료받는 암 환자 중 BNT162b2 mRNA COVID-19 백신의 면역원성과 안전성

Article

Published on 2022-02-072022-09-12
Journal: Journal of the National Cancer Institute [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] activity Adults adverse effect antibody Antibody titer anticancer BNT162b2 mRNA BNT162b2 vaccine Cancer cancer patient Chemotherapy combinations conducted control group COVID-19 Cutoff determine dose effective greater healthy immune Immune checkpoint inhibitor immunogenicity Immunoglobulin measure medication MOST Patient patients Patients with cancer proportion Protective questionnaire reported Retrospective study Safe Safety SARS-CoV-2 seronegative seropositive Side effect significantly significantly lower solid tumor statistical test statistically targeted therapy the SARS-CoV-2 titer treated treated patient Treatment vaccination Vaccine was collected were measured
[DOI] 10.1093/jnci/djab174 PMC 바로가기 [Article Type] Article

Development and multi-center clinical trials of an up-converting phosphor technology-based point-of-care (UPT-POCT) assay for rapid COVID-19 diagnosis and prediction of protective effects

신속한 CovID-19 진단 및 보호 효과의 예측을위한 UPT-POCT (Up-Converting Phosphor Technology-CARE) 분석의 개발 및 다중 센터 임상 시험

Clinical Trial

Published on 2022-02-032022-09-01
Journal: BMC Microbiology [Category] COVID19(2023년), Fulltext, MERS, SARS, 임상, 진단, 치료기술, 치료제,

[키워드] Accuracy antibody Chain Reaction China clinical trial clinically Concentration correlation COVID-19 COVID-19 cases COVID-19 diagnosis COVID-19 patient COVID-19 patients Critical cross-reaction cross-reactions Cutoff defined development ELISA evaluated healthy hospital inactivated indicated intensity lateral flow lateral flow strip microneutralization Microneutralization assay NAb titer NAb titers Neutralizing activity neutralizing antibody OD value OD values Patient performed POCT point-of-care Polymerase chain reaction test positive protective effect Protective effects quantitation Quantitative RBD RBD-specific antibodies RBD-specific antibody RBD-specific total antibodies Reactions Receptor-binding domain recovered patient recovered patients Result reveal reverse transcriptase SARS-CoV-2 SARS-CoV-2 spike protein Sensitivity and specificity serum sample serum samples Seven significantly specific antibodies Spike protein supplementary material test results the antibody the receptor-binding domain total antibodies total antibody Up-conversion phosphor technology vaccinee vaccinees viruses was determined
[DOI] 10.1186/s12866-022-02450-z PMC 바로가기 [Article Type] Clinical Trial

Incidental Findings Suggestive of COVID-19 Pneumonia in Oncologic Patients Undergoing 18 F-FDG PET/CT Studies: Association Between Metabolic and Structural Lung Changes

18 F-FDG PET/CT 연구를 받고 있는 종양 환자에서 COVID-19 폐렴을 암시하는 부수적 발견: 대사 및 구조적 폐 변화 사이의 연관성

Clinical Investigation

Published on 2022-02-012022-09-12
Journal: Journal of Nuclear Medicine [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] ¹⁸F-FDG PET/CT 95% CI Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 added Analysis association Asymptomatic Cancer cancer patient Cancer patients categories category Cell change changes in characteristic clinical forms coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pneumonia CT scans CT sign CT signs Cutoff described diagnose diagnosis of COVID-19 diagnostic value early diagnosis finding gold gold standard help high risk host response identify implication information knowledge lung lung infiltrate lung infiltrates lung parenchyma metabolic metabolic activity molecular Mortality nonspecific Novel coronavirus novel coronavirus disease pandemic pathogenic Patient patients pet PET/CT Pneumonia prognostic pulmonary pulmonary infiltrate pulmonary infiltrates pulmonary involvement radiologic Reporting Research selected severe acute respiratory syndrome Coronavirus specificity subpopulation SUV System Transmission Visual
[DOI] 10.2967/jnumed.121.261915 PMC 바로가기 [Article Type] Clinical Investigation

Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial

보조제 서브유닛 단백질 COVID-19 백신, SCB-2019의 효능: 2상 및 3상 다기관, 이중 맹검, 무작위 배정, 위약 대조 시험

Clinical Trial

Published on 2022-01-292022-09-11
Journal: Lancet (London, England) [Category] 변종, 임상,

[키워드] 1:1 95% CI alum assigned baseline Belgium biopharmaceutical Brazil caused chloride circulating Clover Coalition country COVID 19 COVID-19 COVID-19 case COVID-19 vaccine CpG Cutoff dose doses double-blind effective vaccine Effective vaccines Efficacy efficacy analysis elicited Endpoint enrolled EudraCT exclusion FIVE follow-up period groups Health health condition injection injection site pain intramuscular dose Local median Mild-to-moderate moderate-to-severe COVID-19 MOST multicentre notable Older pandemic participant per-protocol per-protocol population Phase 2 Placebo placebo recipients placebo-controlled trial predominant primary endpoints Protein provide randomisation randomised Randomly receive Registered RT-PCR Safe SAR-CoV-2 SARS CoV SARS-CoV-2 SCB-2019 second dose seronegative participant Seropositivity severe COVID-19 severity Sodium chloride South Africa subset subunit systemic adverse event systemic adverse events Vaccine vaccine efficacy vaccinee vaccinees variant virus virus variants viruses was done
[DOI] 10.1016/S0140-6736(22)00055-1 PMC 바로가기 [Article Type] Clinical Trial

Components of the Mediterranean Diet and Risk of COVID-19

Nutrition

Published on 2022-01-242022-10-31
Journal: Frontiers in Nutrition [Category] COVID-19,

Serological evaluation of patients with coronavirus disease-2019 in Daegu, South Korea

코로나 바이러스 질병 환자의 혈청 학적 평가, 2019 년 대구, 한국 Daegu

Research Article

Published on 2022-01-202022-09-10
Journal: PLoS ONE [Category] 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Admission affecting analyzed anti-SARS-CoV-2 antibody antibody Antibody Response Antibody test assays average calculated Chain Reaction Clinical characteristics collected conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critical Cutoff descending diagnostic died disease course elapsed evaluate Factor healthcare identify Infection information introduced MONITOR onset of symptoms Patient patients with COVID-19 polymerase chain polymerase chain reaction poor prognosis Prevent Quantitative analysis Real-Time Reverse Transcription Polymerase Chain Reaction respiratory response reverse transcription RT-PCR SARS-CoV-2 SARS-CoV-2 antibody test serological response serum sample severe acute respiratory syndrome Coronavirus Sex significant difference significantly more South Korea Spread symptom onset the antibody response Treatment understanding utility Vaccine without symptoms
[DOI] 10.1371/journal.pone.0262820 PMC 바로가기 [Article Type] Research Article

Association between plasma glycocalyx component levels and poor prognosis in severe influenza type A (H1N1)

Article

Published on 2022-01-072022-10-04
Journal: Scientific Reports [Category] 바이오마커, 신종인플루엔자,

[키워드] 28-day mortality acute lung injury Admission albumin levels Analysis APACHE II association blood sample cause Clinical data collected component contribute correlated Cutoff demonstrated determine disease severity Diseases Disruption endothelial Factor H1N1 H1N1 influenza healthy control hospital indicated Influenza influenza A influenza type A interleukin-6 Lactate mild cases organ dysfunction Patient patients with influenza plasma poor prognosis positively correlated Predictive Predictive markers prospective observational study sensitivity Sepsis severity significantly higher SOFA score specificity survival Syndecan-1 tumor necrosis factor-α viral infection virus infection were measured
[DOI] 10.1038/s41598-021-04146-2 PMC 바로가기 [Article Type] Article

Analytical Performance of Quantitative DiaSorin Liaison SARS-COV-2 Antigen Test for the Asymptomatic Population

무증상 집단에 대한 정량적 DiaSorin 연락 SARS-COV-2 항원 테스트의 분석 성능

Public Health

Published on 2022-01-072022-09-11
Journal: Frontiers in Public Health [Category] MERS, SARS, 치료기술,

[키워드] Antigen antigen detection Asymptomatic asymptomatic patients automated chemiluminescence conducted coronavirus coronavirus 2 correlation COVID-19 infection Cutoff cycle threshold Diagnosis DiaSorin evaluate exceeded facilitate flexibility group identify material milliliter molecular monitoring population nasal swab nasal swabs negative sample NPs pandemic Patient performance Population positive Rapid reached respiratory Retrospective study reverse transcriptase risk RT-PCR Sample SARS-CoV-2 sensitivity Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specificity TCID Test tested tissue culture Tissue Culture Infectious Dose Variability Viral Viral load
[DOI] 10.3389/fpubh.2021.788581 PMC 바로가기 [Article Type] Public Health

The Predictive Role of NLR, d-NLR, MLR, and SIRI in COVID-19 Mortality

Article

Published on 2022-01-062022-10-31
Journal: Diagnostics [Category] COVID-19,