Modelling RT-qPCR cycle-threshold using digital PCR data for implementing SARS-CoV-2 viral load studiesSARS-CoV-2 바이러스 부하 연구를 구현하기 위해 디지털 PCR 데이터를 사용하여 RT-qPCR 주기 임계값 모델링Research Article Published on 2021-12-202022-09-12 Journal: PLoS ONE [Category] SARS, 진단, [키워드] Accuracy age assays calculated Cohort Ct values cycle threshold Cycle threshold value Cycle threshold values dataset Diagnosis diagnostic Diagnostic method digital PCR epidemiological situation expressed feature Gender Health authority high risk Italy Linear regression model logistic regression model objective observational studies observational study Patient platform positive sample Predictive Probability public health randomly divided resource Result Retrospective study RT-qPCR SARS-CoV-2 SARS-CoV-2 viral load sensitivity specificity subset threshold training set Viral load was used [DOI] 10.1371/journal.pone.0260884 PMC 바로가기 [Article Type] Research Article
Limited Sensitivity of a Rapid SARS-CoV-2 Antigen Detection Assay for Surveillance of Asymptomatic Individuals in Thailand태국에서 무증상 개체의 감시를위한 빠른 SARS-COV-2 항원 검출 분석의 제한된 민감도Articles Published on 2021-12-112022-09-10 Journal: The American Journal of Tropical Medicine and Hygi [Category] MERS, SARS, 진단, 치료기술, [키워드] 95% CI Accuracy activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antigen asymptomatic individual caused Chain Reaction community transmission Control coronavirus COVID-19 COVID-19 outbreak Cycle threshold value detection determined by disease disease control evaluated Factor feasibility global pandemic highlight individual Infectious disease Limited Logistic Mass screening National operators Outbreaks performed polymerase chain polymerase chain reaction Prevention and control Public public health Rapid Rapid test respiratory SARS-CoV-2 SARS-CoV-2 antigen second wave sensitivity severe acute respiratory syndrome Coronavirus specificity Surveillance temperature Validity Viral Viral load viral loads [DOI] 10.4269/ajtmh.21-0809 PMC 바로가기 [Article Type] Articles
Changes in peripheral blood in SARS CoV-2 patients and its clinico-pathological correlation: A prospective cross-sectional studyArticle Published on 2021-12-012023-06-19 Journal: International journal of laboratory hematology [Category] MERS, SARS, [키워드] Clinical severity COVID-19 Cycle threshold value morphological changes peripheral blood smear [DOI] 10.1111/ijlh.13720 PMC 바로가기
Cycle threshold values in RT-PCR to determine dynamics of SARS-CoV-2 viral load: An approach to reduce the isolation period for COVID-19 patientsArticle Published on 2021-12-012023-07-02 Journal: Journal of medical virology [Category] SARS, [키워드] COVID 19 Cycle threshold value Isolation RT-PCR SARS-CoV-2 [DOI] 10.1002/jmv.27206 PMC 바로가기
Nanopore metagenomic sequencing for detection and characterization of SARS-CoV-2 in clinical samples임상 샘플에서 SARS-COV-2의 검출 및 특성화를위한 나노 포어 메타 게놈 시퀀싱Research Article Published on 2021-11-182022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 변종, 치료기술, 치료제, [키워드] Alpha Analysis assays characterization Classifier clinical sample clinical samples Complete concern Concordance COVID-19 pandemic Cycle threshold value diagnostic feasibility future work Gamma Genome less Lineage metagenomic sequencing Nanopore objective pathogen Pathogens PCR performed Phylogenetic Phylogenetic analysis positive Result RT-PCR SARS-CoV-2 sensitivity specificity specimen specimens Support variant variants Viral viral pathogens VoC was performed [DOI] 10.1371/journal.pone.0259712 PMC 바로가기 [Article Type] Research Article
Prolonged SARS-CoV-2 Positivity in Immunocompetent Patients: Virus Isolation, Genomic Integrity, and Transmission Risk면역적격 환자에서 장기간 SARS-CoV-2 양성: 바이러스 분리, 게놈 무결성 및 전파 위험Research Article Published on 2021-11-172022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed approach Asymptomatic Cell culture cell cultures coronavirus correlation COVID-19 COVID-19 case COVID-19 nucleic acid testing current Cycle threshold value demonstrated evaluated Genome genomic hospitals humoral immune response Hypothesis immunocompetent implication individual individuals Infectious virus infectious viruses integrity Isolation long-lasting nasopharynx no correlation nursing homes Patient persistence positive positive result Prolonged replication-competent viruses respiratory reverse transcription PCR risk rRT-PCR RT-PCR SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 transmission Sequencing serological response severe acute respiratory syndrome Coronavirus social isolation symptom onset symptomatic tested These data upper respiratory tract virus virus isolation Virus shedding viruses [DOI] 10.1128/Spectrum.00855-21 PMC 바로가기 [Article Type] Research Article
Sampling site for SARS-CoV-2 RT-PCR—An intrapatient four-site comparison from Tampere, FinlandSARS-COV-2 RT-PCR 용 샘플링 사이트-핀란드 탬퍼에서의 4 개 사이트 비교.Research Article Published on 2021-11-162022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료기술, [키워드] analysed anatomical Anterior can be used collected COVID-19 positive patient Cycle threshold value Cycle threshold values Diagnosis heterogeneity nasal Nasal sample nasal swab nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs nasopharynx no significant difference objective Oropharyngeal oropharynx patients positive provided recruited Result RT-PCR Saliva sampling SARS-CoV-2 SARS-CoV-2 detection significant difference situation Swab written Informed Consent [DOI] 10.1371/journal.pone.0260184 PMC 바로가기 [Article Type] Research Article
Symptom- and Prevention-Based Testing of COVID-19 in Nursing Home Residents: A Retrospective Cohort StudyOriginal Manuscript Published on 2021-11-112022-10-31 Journal: Gerontology and Geriatric Medicine [Category] COVID-19, [키워드] clinical contribute COVID-19 cycle Cycle threshold value decrease develop fatigue groups home in both groups increase in increased mortality investigated long-term care facilities measure medical records not differ Nursing nursing home occurred Older adults oxygen saturation remained resident SARS-CoV-2 SARS-CoV-2 RT-PCR somnolence Symptom Symptoms temperature tested Testing threshold Transmission with COVID-19 [DOI] 10.1177/23337214211055338 PMC 바로가기 [Article Type] Original Manuscript
COVID-19 Breakthrough Infections and Transmission Risk: Real-World Data Analyses from Germany’s Largest Public Health Department (Cologne)Article Published on 2021-11-022022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] age Asymptomatic Breakthrough infection breakthrough infections calculated clinical trials close contact combating Complete Control control group Course COVID-19 COVID-19 vaccine Cycle threshold value Department doses explained Factor first vaccination Health Infection Male sex Measures occurred pandemic Patient patients Public R 2 real-world data risk SARS-CoV-2 pandemic SARS-CoV-2 transmission Sex Symptom the SARS-CoV-2 virus Transmission vaccination virus [DOI] 10.3390/vaccines9111267 PMC 바로가기 [Article Type] Article
Anti-spike antibody response to natural SARS-CoV-2 infection in the general population일반 인구에서 자연적인 SARS-CoV-2 감염에 대한 항스파이크 항체 반응Article Published on 2021-10-292022-09-12 Journal: Nature Communications [Category] MERS, SARS, 진단, [키워드] anti-spike antibodies anti-Spike IgG antibody antibody levels Antibody Response Antibody responses average Bayesian booster Community COVID-19 infection Cycle threshold value determinant determinants Epidemiology estimate feature female General population immune response infected with SARS-CoV-2 Infection latent class less linear MOST Older participant PCR tests peak level Planning positive swab Reinfection reported responders risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR test seroconvert seroconverted Severe infection subsequent Symptoms the antibody response trajectory understanding United Kingdom vaccination viral burden viral infection [DOI] 10.1038/s41467-021-26479-2 PMC 바로가기 [Article Type] Article