SARS-CoV-2 Nsp5 Activates NF-κB Pathway by Upregulating SUMOylation of MAVS
Immunology
[키워드] activating
Activation
attenuate
Calu-3
caused
cells
clinical study
COVID-19
cytokine
cytokine expression
cytokine production
effector
ENhance
expression
IL-1β
IL-2
IL-6
increase
induce
infected with SARS-CoV-2
Infectious disease
inhibitor
investigated
knockdown
MAVS
molecular mechanism
NF-κB
NF-κB
NF-κB activation
NF-κB signaling
nsp5
overexpression
pathway
Patient
pro-inflammatory cytokine
promote
Protein
protein level
Research
SARS-CoV-2
SARS-COV-2 infection
stability
SUMOylation
the disease
TNF-α
Treatment
triggering
upstream
[DOI] 10.3389/fimmu.2021.750969 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2021.750969 PMC 바로가기 [Article Type] Immunology