death in COVID-19

[키워드] Analysis baseline blocks pro-inflammatory activity cause of death co-primary endpoints Cohort coronavirus COVID-19 COVID-19 patients dataset death death in COVID-19 drug toxicity effective enrolled EudraCT evaluated expected exploratory greater IL-6 intention-to-treat Interaction interleukin interleukin-6 involved ITT lethality rate lethality rates mechanical respiratory Mortality multicenter multivariable logistic regression NCT04317092 negatively affected null hypothesis Older age PaO2/FiO2 ratio Pathogenesis Patient patients patients with COVID-19 Phase 2 Pneumonia pro-inflammatory activity prognostic variable prognostic variables prospective cohort Prospective trial reduced Registration reported respiratory Respiratory Support Result Safety single-arm statistically significant Steroids subject Support survival Tocilizumab TOCIVID-19 Toxicity Trial use of steroid was used
[DOI] 10.1186/s12967-020-02573-9 PMC 바로가기 [Article Type] Research