Complex interaction between mutant HNRNPA1 and gE of varicella zoster virus in pathogenesis of multiple sclerosisReview Published on 2018-06-012023-05-31 Journal: Autoimmunity [Category] 두창, 수두, 홍역, [키워드] Demyelination hnRNPA1 M9 domain multiple sclerosis prion-like domain Varicella zoster virus [DOI] 10.1080/08916934.2018.1482883 [Article Type] Review
MicroRNA-155 enhances T cell trafficking and antiviral effector function in a model of coronavirus-induced neurologic diseaseResearch Published on 2016-09-072023-06-13 Journal: Journal of Neuroinflammation [Category] MERS, [키워드] Demyelination miR-155 Neuroinflammation T cells virus [DOI] 10.1186/s12974-016-0699-z PMC 바로가기 [Article Type] Research
Remyelination Is Correlated with Regulatory T Cell Induction Following Human Embryoid Body-Derived Neural Precursor Cell Transplantation in a Viral Model of Multiple SclerosisResearch Article Published on 2016-06-162022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] CD4+ T cell Cell cell line Central nervous system Clinical improvement Clinical outcome clinical recovery comparison conditions correlated Critical Culture Demyelination described determine disease effective Effectiveness embryoid embryonic Factor Gene Expression Genetic Human improvement increase in induction injection lymphatics mice Model mouse hepatitis virus Multiple multiple sclerosis Neural Neuroinflammation neurologic neurotropic NPC precursor reduced Regulatory T cell remyelination sclerosis stem cell sustained therapeutic potential transplantation Tregs unique viral-induced [DOI] 10.1371/journal.pone.0157620 PMC 바로가기 [Article Type] Research Article
Is It worth Considering Circulating microRNAs in Multiple Sclerosis?Review Published on 2016-04-052023-08-30 Journal: Frontiers in Immunology [Category] E형 간염, [키워드] Biomarkers circulating miRNAs Demyelination Exosomes Extracellular vesicles Inflammation multiple sclerosis relapses [DOI] 10.3389/fimmu.2016.00129 PMC 바로가기 [Article Type] Review
Inflammatory Cytokines Are Involved in Focal Demyelination in Leprosy Neuritis염증성 사이토카인이 나병 신경염의 국소 탈수초화에 관여한다journal-article Published on 2016-03-012024-08-01 Journal: Journal of Neuropathology & Experimental Neurology [Category] 한센병, [키워드] Demyelination IL-23 leprosy Mycobacterium leprae Neuropathy Schwann cell tumor necrosis factor [DOI] 10.1093/jnen/nlv027 [Article Type] journal-article
Self-reactive CD4 + T cells activated during viral-induced demyelination do not prevent clinical recoveryResearch Published on 2015-11-112023-06-13 Journal: Journal of Neuroinflammation [Category] MERS, [키워드] antigen-presenting cells Autoimmunity CD4 T cells Central nervous system Demyelination viral infection [DOI] 10.1186/s12974-015-0426-1 PMC 바로가기 [Article Type] Research
Mouse Hepatitis Virus Infection Upregulates Genes Involved in Innate Immune ResponsesResearch Article Published on 2014-10-312022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] activated Activation acute phase Affymetrix Analysis binding calcium ion caused CD11b CD19 CD4 CD52 CD68 CD74 CD8 Cell cellular changes in CNS contribute demonstrated Demyelination expression IFN-γ IL-12 increased expression induce Infection Inflammation inflammatory mediator Innate Local maturation mice microenvironment microglia morphology mouse mRNA expression myelin sheath phagocytosis regulate released response reveal robust significantly turn upregulated viral replication [DOI] 10.1371/journal.pone.0111351 PMC 바로가기 [Article Type] Research Article
Alterations in Nerve-Evoked Bladder Contractions in a Coronavirus-Induced Mouse Model of Multiple SclerosisResearch Article Published on 2014-10-132022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] agonist alteration ATP Bethanechol bladder bladder dysfunction bladder strips blocked cause changes in CNS Combination contractile contraction controls Demyelination disease EFS help male mice Model mouse mucosa Multiple multiple sclerosis muscarinic neurodegenerative not significantly different pathologic pathological change performed physiological receptor receptors reduced removal respond restored Result resulting sclerosis significantly significantly increased Symptom tension underlie urgency urinary frequency Urinary tract [DOI] 10.1371/journal.pone.0109314 PMC 바로가기 [Article Type] Research Article
FTY720 (fingolimod) modulates the severity of viral-induced encephalomyelitis and demyelinationResearch Published on 2014-08-202022-10-30 Journal: Journal of Neuroinflammation [Category] Coronavirus, [키워드] Affect Anti-viral immune response approved CD4+ CD8+ T cell Central nervous system clinical disease CNS correlated cytokine production cytolytic Demyelination disease disease severity disease-causing dose drug Effect effective examined exhibited expression flow cytometry food FTY720 IFN-γ infiltration Inflammatory inhibiting Lymph node lymphocyte mice Migration modulate morbidity and mortality Mortality mouse hepatitis virus multiple sclerosis Neuroinflammation neurologic neurotropic not affect occur Patient Post-infection proliferation recorded reduce reduction in Result S1P receptor severity staining T lymphocyte T lymphocytes Therapeutic benefit TNF-α treated Treatment viral replication viral-induced virus virus-specific T cell was determined were infected [DOI] 10.1186/s12974-014-0138-y PMC 바로가기 [Article Type] Research
The TIM-3 pathway ameliorates Theiler’s murine encephalomyelitis virus-induced demyelinating diseaseTIM-3 경로는 타일러의 쥐 뇌척수염 바이러스 유발 탈수성 질병을 개선합니다.journal-article Published on 2014-07-012024-08-25 Journal: International Immunology [Category] 폴리오, [키워드] Demyelination Galectin-9 multiple sclerosis T-cell immunoglobulin and mucin domain-3 Theiler’s murine encephalomyelitis virus-induced demyelinating disease. [DOI] 10.1093/intimm/dxt056 [Article Type] journal-article