Clinical characteristics of the Omicron variant – results from a Nationwide Symptoms Survey in the Faroe IslandsArticle Published on 2022-09-012022-11-16 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] acute phase appear asked Asymptomatic Characteristics chill clinical Clinical characteristics, Faroe Islands conducted confidence interval Control control group controls COVID COVID-19 cross-sectional dominant fatigue Fever illness individual Infection infections island less Mild moderate MOST omicron Patient Positive test question questionnaire reported risk SARS-CoV-2 severe disease severity survey Symptom Symptoms variant variants [DOI] 10.1016/j.ijid.2022.07.005 PMC 바로가기
Whole-genome sequencing of SARS-CoV-2 reveals diverse mutations in circulating Alpha and Delta variants during the first, second, and third waves of COVID-19 in South Kivu, east of the Democratic Republic of the CongoResearch article Published on 2022-09-012022-10-05 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] A.23.1 Analysis B.1.351 B.1.617.2 circulating circulation coding sequence consensus genome COVID-19 D614G Delta delta variant Diagnosis disease severity dominant Genes Genetic evolution Genetic variation genome coverage genomic global pandemic highlight identify include information isolate Lineage management mapped molecular MOST Mutation nucleocapsid protein objective ORF1ab ORF3 outbreak Oxford P.1 pandemic pangolin Phylogenetic analysis Point mutation processed reference genome responsible Result reveal SARS-CoV-2 SARS-CoV-2 isolate sequence sequenced Sequencing Seven South South Kivu subsequent Surveillance synonymous the SARS-CoV-2 genome Treatment variant variants were used whole-genome sequencing Wuhan [DOI] 10.1016/j.ijid.2022.05.041 [Article Type] Research article
High Sensitivity and NPV for BinaxNOW Rapid Antigen Test in Children at a Mass Testing Site during Prevalent Delta Variant PeriodArticle Published on 2022-08-312022-11-16 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI Abbott Antigen Asymptomatic children COVID-19 COVID-19 test Delta develop dominant Efficacy evaluated increasingly mass nare Negative predictive value NPV participant Participants PCR pediatric pediatric rapid antigen testing. performed Period positive Positive predictive value PPV predominant presenting Rapid reported RT-PCR Safe SARS-CoV-2 sensitivity Site specificity swabs symptom status symptomatic and asymptomatic symptomatic participants Test tested Testing variant Viral load [DOI] 10.1128/spectrum.00236-22 PMC 바로가기
Dysregulated naïve B cells and de novo autoreactivity in severe COVID-19Article Published on 2022-08-312022-10-05 Journal: Nature [Category] SARS, 변종, 진단, 치료법, [키워드] Activation Analysis antibody antibody secreting cell Antigen ASC Autoantigens autoreactive antibody B cell breadth clinically COVID-19 de novo dominant feature Frequency glomerular identify IgG1 immune activation implication Inflammatory Intervention membrane Mild naïve B cell nuclear pathogenic autoantibody pathologic pathway Patient persist Proteins question raising remained response reveal SARS-CoV-2 selective serological severe COVID-19 severe disease single-cell specificity subset symptom onset Tolerance Treatment [DOI] 10.1038/s41586-022-05273-0 [Article Type] Article
Differential Impact of SARS-CoV-2 Isolates, Namely, the Wuhan Strain, Delta, and Omicron Variants on ErythropoiesisArticle Published on 2022-08-312022-11-16 Journal: Microbiology Spectrum [Category] SARS, 변종, [키워드] ACE2 Affect Blood blood circulation Bone marrow CD45 CD8 Cell COVID-19 patient COVID-19 patients degranulation Delta disease severity dominant erythropoiesis erythropoiesis. Express expressing expression Frequency function functions granzyme hallmark Hematopoiesis hypoxia immature immunosuppressive immunosuppressive properties Impact impair in vitro investigated omicron oxygen Patient prevalent provide RBC RBCs reactive oxygen specy receptor red blood cell reversed ROS SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant SARS-CoV-2 variants significantly strain subpopulation suppress T cell the SARS-CoV-2 these cell tissues TMPRSS2 Transmissibility variant variants Wuhan Wuhan strain [DOI] 10.1128/spectrum.01730-22 PMC 바로가기
Increased transmissibility of SARS-CoV-2 alpha variant (B.1.1.7) in children: three large primary school outbreaks revealed by whole genome sequencing in the NetherlandsArticle Published on 2022-08-292022-11-16 Journal: BMC Infectious Diseases [Category] SARS, 변종, [키워드] affected Alpha Antigen Asymptomatic attack attack rate B.1.1.7 B.1.1.7 variant B.1.617.2 children contributed defined described dominant Evidence Genotype household contact household contacts incidence Increased infected children Infection prevention Infection prevention and control investigated lack majority mandatory Netherland Netherlands outbreak Outbreaks peak physical distancing polymerase chain positive primary school promote provide Public random SAR SARS-CoV-2 School secondary attack rate Sequencing service South Specific Transmissibility Transmissibility in children. transmissibility of SARS-CoV-2 Transmission urgency variant variants Ventilation VoC was performed whole genome Whole genome sequencing [DOI] 10.1186/s12879-022-07623-9 PMC 바로가기
Charlson comorbidity index, neutrophil-to-lymphocyte ratio and undertreatment with renin-angiotensin-aldosterone system inhibitors predict in-hospital mortality of hospitalized COVID-19 patients during the omicron dominant periodArticle Published on 2022-08-252022-11-15 Journal: Frontiers in Immunology [Category] 진단, [키워드] 95%CI absence analyzed Angiotensin-converting enzyme angiotensin-converting enzyme inhibitor angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers ARBs blocker Care CCI Charlson comobidity index clinician Comorbidity Coronavirus disease 2019 COVID-19 COVID-19 patient cut-off value died discharged dominant echocardiographic Endpoint greater help high-risk patient Hospital admission Hospitalization Hospitalized hospitalized COVID-19 patient hospitalized patient in-hospital mortality Infection inhibitor Laboratory laboratory-confirmed males Mortality mortality risk Neutrophil-to-lymphocyte ratio NLR Older omicron Patient physical predict predicted predictor Prevalence prognostic indicator Radiographic receptor reduce risk stratification significantly the primary endpoint therapy [DOI] 10.3389/fimmu.2022.958418 PMC 바로가기
SARS-CoV-2 Genetic Diversity and Lineage Dynamics in Egypt during the First 18 Months of the PandemicArticle Published on 2022-08-252022-11-16 Journal: Viruses [Category] SARS, 변종, [키워드] adaptive analyzed COVID-19 death diagnosed Diversity dominant Dynamics Egypt Epidemiology Genome genomic Genomic epidemiology highlight Immunity Infection introduced Lineage lineages Month Mutation National pandemic Phylogenetic predominant Prevent public health measure Region reported responsible SARS-CoV-2 sequence subset Surveillance Vaccinations VoC whole-genome [DOI] 10.3390/v14091878 PMC 바로가기
Managing an evolving pandemic: Cryptic circulation of the Delta variant during the Omicron rise진화하는 전염병 관리: 오미크론 상승 중 Delta 변종의 비밀 순환Article Published on 2022-08-252022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Chain Reaction Characteristics circulation decrease Delta delta variant diminishe dominant eliminated Epidemiology expected Increases indicated initial maintain managing morbidity Mutation omicron Omicron variant pandemic polymerase chain polymerase chain reaction Quantitative real time reverse transcriptase Reverse transcriptase quantitative polymerase chain reaction RT-qPCR SARS-CoV-2 side Spread Susceptible-infected-recovered model variant variants variants of concern Wastewater-based epidemiology [DOI] 10.1016/j.scitotenv.2022.155599 PMC 바로가기 [Article Type] Article
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Naturally Acquired Immunity versus Vaccine-induced Immunity, Reinfections versus Breakthrough Infections: A Retrospective Cohort Study중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 자연 획득 면역 대 백신 유도 면역, 재감염 대 돌발 감염: 후향적 코호트 연구Observational Study Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 임상, [키워드] 95% CI 95% confidence interval Acquired acquired immunity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 applied BNT162b2 BNT162b2 vaccine Breakthrough infection caused coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 delta variant demonstrated dominant dose Evidence evidence of examined Hospitalization Immunity increased risk individual individuals induced immunity infected individual infected individuals Infection inoculation mRNA BNT162b2 vaccine multivariate logistic regression Naturally naturally acquired immunity observational study occur occurred regimen Reinfection respiratory retrospective SARS-CoV-2 severe acute respiratory syndrome Coronavirus symptomatic disease vaccination Vaccine Vaccine-induced immunity vaccinee [DOI] 10.1093/cid/ciac262 PMC 바로가기 [Article Type] Observational Study