Repurposing of the antibiotic nitroxoline for the treatment of mpoxArticle Published on 2023-03-012023-06-10 Journal: Journal of medical virology [Category] 원숭이두창, [키워드] antiviral drugs antiviral therapy chelator Drug repurposing Monkeypox orthopoxvirus poxvirus [DOI] 10.1002/jmv.28652
The management of Babesia, amoeba and other zoonotic diseases provoked by protozoaReview Published on 2023-03-012023-06-22 Journal: Expert opinion on therapeutic patents [Category] 조류인플루엔자, [키워드] antiprotozoal drug Babesia Drug repurposing Entamoeba histolytica, zoonosis Protozoa [DOI] 10.1080/13543776.2023.2205586 [Article Type] Review
Monkeypox and drug repurposing: seven potential antivirals to combat the viral diseaseArticle Published on 2023-02-222023-06-10 Journal: Reviews on environmental health [Category] 원숭이두창, [키워드] antivirals brincidofovir Drug repurposing Monkey Pox mpox orthopoxviruses Pharmaceuticals tecovirimat [DOI] 10.1515/reveh-2023-0001
Drug Repurposing: An Effective Tool in Modern Drug DiscoveryArticle Published on 2023-02-212024-09-05 Journal: Russian Journal of Bioorganic Chemistry [Category] update2024, [키워드] clinical trials Drug discovery Drug repurposing molecular docking post-market safety [DOI] 10.1134/S1068162023020139 PMC 바로가기 [Article Type] Article
DRaW: prediction of COVID-19 antivirals by deep learning—an objection on using matrix factorizationarticle Published on 2023-02-152024-09-05 Journal: BMC Bioinformatics [Category] update2024, [키워드] COVID-19 deep learning Drug repurposing matrix factorization [DOI] 10.1186/s12859-023-05181-8 PMC 바로가기 [Article Type] article
Potential treatments of COVID-19: Drug repurposing and therapeutic interventionsFull Paper Published on 2023-02-152024-09-05 Journal: Journal of pharmacological sciences [Category] update2024, [키워드] clinical trials COVID-19 Drug repurposing SARS-CoV-2 Vaccines [DOI] 10.1016/j.jphs.2023.02.004 PMC 바로가기 [Article Type] Full Paper
Discovery of adapalene and dihydrotachysterol as antiviral agents for the Omicron variant of SARS-CoV-2 through computational drug repurposingArticle Published on 2023-02-012023-07-09 Journal: Molecular diversity [Category] COVID19(2023년), [키워드] Adapalene Drug repurposing Omicron variant SARS-CoV-2 Vitamin D [DOI] 10.1007/s11030-022-10440-6 PMC 바로가기
Methotrexate inhibition of SARS-CoV-2 entry, infection and inflammation revealed by bioinformatics approach and a hamster modelArticle Published on 2022-12-212023-07-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), [키워드] Drug repurposing Inflammation methotrexate multi-target drugs. SARS-CoV-2 [DOI] 10.3389/fimmu.2022.1080897 PMC 바로가기
3D Ex vivo tissue platforms to investigate the early phases of influenza a virus- and SARS-CoV-2-induced respiratory diseasesArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 신약개발, 진단, 치료제, [키워드] animal model animal models Antiviral Cell Cell culture comparable consequence Drug repurposing drug target early phase Ex vivo ex vivo infection Ex vivo infection model Health Host human lung IAV in vitro Infection Inflammatory cytokine Influenza influenza A virus Influenza virus Innate immunity interferon interferon response Intervention introduced lung tissue morbidity and mortality murine outbreak pathophysiological pharmacological platform Respiratory disease respiratory viruses responses SARS-CoV-2 therapy tissue Treatment viral infection viral life cycle viral replication virus while [DOI] 10.1080/22221751.2022.2117101 PMC 바로가기
Genomic variants-driven drug repurposing for tuberculosis by utilizing the established bioinformatic-based approachShort communication Published on 2022-12-012022-10-05 Journal: Biochemistry and Biophysics Reports [Category] 신약개발, [키워드] annotations applied approach bioinformatics biological process CCR5 CD44 cellular component contribute CXCR4 demonstrated deregulation disease disease-associated drug Drug discovery Drug repurposing drug target evaluated Evidence facilitate functional functional annotation Genes genomic genomic variant genomic variants GWAS HLA-B identify implementation in-silico indication involved KEGG Missense mutation molecular overlapped Pathogenesis Pathway analysis provided risk SELP suggested target Treatment Tuberculosis variant [DOI] 10.1016/j.bbrep.2022.101334 [Article Type] Short communication