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Prevalence of SARS-CoV-2 Antibodies in Laboratory Healthcare Workers at Assiut University Hospital, Egypt

이집트 아시우트 대학 병원의 실험실 의료 종사자에서 SARS-CoV-2 항체의 유병률

Article

Published on 2022-05-062022-09-11
Journal: Journal of Environmental and Public Health [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,

Control of CDH1/E-Cadherin Gene Expression and Release of a Soluble Form of E-Cadherin in SARS-CoV-2 Infected Caco-2 Intestinal Cells: Physiopathological Consequences for the Intestinal Forms of COVID-19

SARS-CoV-2에 감염된 Caco-2 장 세포에서 CDH1/E-Cadherin 유전자 발현 및 가용성 형태의 E-Cadherin 방출 제어: COVID-19의 장 형태에 대한 생리병리학적 결과

Article

Published on 2022-05-042022-09-11
Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 치료기술, 치료제,

[키워드] 24 hour 24 hours 48 hour 48 hours ACE2 ACE2 mRNA Affect AT1 Caco-2 Caco-2 cell Caco-2 cells cadherin CDH1 Cell cell line cells Co-receptor connexin consequence contributing to Control COVID-19 Culture culture supernatant diarrhoea diarrhoea) digestive tract Disruption dissemination down-regulated dysregulation E-cadherin ENCODE epithelial exposure to expresse expression form Gastrointestinal symptom gastrointestinal symptoms gastrointestinal tract HCoV HCoV-OC43 HLA class I human ACE2 illnesses in viral induce infected with SARS-CoV-2 Infection intestinal Intestinal barrier intestinal cells intestinal tissue intranasal involved JAMA junctions leads membrane mRNA mRNA expression OC43 occludin pandemic Patient Physiopathological Post-infection Protein receptor receptor ACE2 Release remained reported respiratory respiratory tract SARS-CoV-2 SARS-COV-2 infection significant increase significantly lower Symptom the disease these symptoms TMPRSS2 Transcription transgenic mice Trigger Viral viral entry virus
[DOI] 10.3389/fcimb.2022.798767 PMC 바로가기 [Article Type] Article

Oral hymecromone decreases hyaluronan in human study participants

경구 hymecromone은 인간 연구 참가자의 hyaluronan을 감소시킵니다

Clinical Trial

Published on 2022-05-022022-09-11
Journal: The Journal of Clinical Investigation [Category] 비임상,

[키워드] 4-methylumbelliferone Accelerator Administered Adults analyzed animal models approved approved drugs Arm asked baseline breath catalyst Concentration conducted COVID-19 infection decrease dose dose-dependent manner doses drug concentration Europe exposure to Extracellular matrix fibrosis glycosaminoglycan greater greater decrease healthy hymecromone hypertension implicated in vitro Inflammation inhibit inhibitor Medicine metabolite NIH Open-label oral other diseases Pathogenesis pathophysiology pulmonary disease pulmonary diseases pulmonary fibrosis pulmonary hypertension reduction in serum significant decrease single-center sputum Stanford study participant subject therapy Tolerability Treatment
[DOI] 10.1172/JCI157983 PMC 바로가기 [Article Type] Clinical Trial

Risk assessment of SARS-CoV-2 infection in free-ranging wild animals in Belgium

벨기에의 방목 야생 동물에서 SARS-CoV-2 감염 위험 평가

Review

Published on 2022-05-012022-09-11
Journal: Transboundary and emerging diseases [Category] COVID19(2023년), SARS, 치료기술,

Shedding light on the toxicity of SARS-CoV-2-derived peptide in non-target COVID-19 organisms: A study involving inbred and outbred mice

비표적 COVID-19 유기체에서 SARS-CoV-2 유래 펩타이드의 독성에 대한 조명: 근친교배 및 근친교배 마우스를 대상으로 한 연구

Article

Published on 2022-05-012022-09-11
Journal: Neurotoxicology [Category] COVID19(2023년), MERS, SARS, 바이오마커, 유전자 메커니즘,

[키워드] acetylcholinesterase activated administration alteration animals antidepressant antioxidant anxiolytic applied biochemical Biomarker Brain C57Bl/6 J mice catalase consequence COVID-19 demonstrated depressive dismutase dispersion Effect Environmental Toxicology evaluate evaluated Evidence evidence of exposure to Field test genetic profile greater homeostasis hydrogen hydrogen peroxide Impact Laboratory locomotor maintain male mammalian mechanism memory memory deficit mice natural environments open oxidative stress Pandemic COVID-19 PCA peptide Principal component principal component analysis Protein Proteins provide reactive reduction in Research response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 particle SARS-CoV-2 particles sensitivity shedding Spike protein Superoxide Superoxide Dismutase Swiss mice. the Spike the vaccine Therapeutic strategies therapeutic strategy Toxicity Viral
[DOI] 10.1016/j.neuro.2022.03.012 PMC 바로가기 [Article Type] Article

Antigen vs RT-PCR Tests for Screening Quarantined Students in Florida During the COVID-19 Pandemic SARS-CoV-2 Delta Variant Surge

COVID-19 팬데믹 SARS-CoV-2 Delta 변종 급증 동안 플로리다에서 격리된 학생을 선별하기 위한 항원 대 RT-PCR 테스트

Article

Published on 2022-05-012022-09-11
Journal: JAMA Pediatrics [Category] COVID19(2023년), SARS, 변종,

[키워드] Antigen Chain Reaction COVID-19 COVID-19 pandemic Delta delta variant exposure to RT-PCR SARS-CoV-2 Screening student Test
[DOI] 10.1001/jamapediatrics.2022.0080 PMC 바로가기 [Article Type] Article

The association between pre-exposure to glucocorticoids and other immunosuppressant drugs with severe COVID-19 outcomes

Research article

Published on 2022-05-012022-10-05
Journal: Clinical microbiology and infection : the official [Category] 치료기술,

[키워드] 1.26 95% CI adjusted Antineoplastic Antineoplastic therapy antineoplastics association Autoimmune diseases baseline biological therapy calculated Cancer cardiac event Chemical cohort study covariate adjustment COVID-19 COVID-19 diagnosis COVID-19 prognosis defined determine diagnosed with COVID-19 dose drug drugs evaluate the effect exposure to glucocorticoid Glucocorticoids High-dose Hospital admission ICU admission Immunocompromised Immunosuppressant immunosuppressants Immunosuppression Immunosuppressive treatment individual individuals Karolinska University Hospital L01 Logistic regression mechanical ventilation Mortality objective outcome outcomes prednisolone equivalent Probability renal Result severe COVID-19 severity stroke Transplant Treatment underlying condition with COVID-19
[DOI] 10.1016/j.cmi.2022.05.014 [Article Type] Research article

Effects of short-term ambient particulate matter exposure on the risk of severe COVID-19

심각한 COVID-19의 위험에 대한 단기 주변 미립자 물질 노출의 영향

Article

Published on 2022-05-012022-09-11
Journal: The Journal of Infection [Category] COVID19(2023년), SARS, 변종,

High T-cell response rate after COVID-19 vaccination in belimumab and rituximab recipients

벨리무맙 및 리툭시맙 수혜자에서 COVID-19 백신 접종 후 높은 T 세포 반응률

Article

Published on 2022-05-012022-09-11
Journal: Journal of autoimmunity [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제,

[키워드] absence All the patient all the patients analyzed anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibody Autoimmune diseases B cell B cells B-cell Belimumab caused circulating comparable completion complex Concentration consecutive patient Control COVID-19 COVID-19 vaccination COVID-19 vaccine detectable anti-SARS-CoV-2 antibodies detectable anti-SARS-CoV-2 antibody diagnostic evaluate evaluated exposure to healthcare personnel immune response immune responses immunogenicity indicate interferon Lupus material median mRNA vaccination mRNA vaccine mRNA vaccines neutralizing capacity Participants Patient patients patients treated positive pseudoviruses RBD receiving recipient recruited retention rituximab RTX SARS-CoV-2 SARS-CoV-2 pseudovirus SARS-CoV-2 pseudoviruses SARS-CoV-2 vaccination significantly lower strain systemic autoimmune disease Systemic autoimmune diseases T cell T-cell Response tested the antibodies the patient therapy Total treated Treatment vaccination Vaccine virus virus-specific cellular immunity
[DOI] 10.1016/j.jaut.2022.102827 PMC 바로가기 [Article Type] Article

Incidence of SARS-CoV-2 infection among COVID-19 vaccinated and unvaccinated healthcare personnel, first responders, and other essential and frontline workers: Eight US locations, January-September 2021

COVID-19 예방 접종 및 예방 접종을 받지 않은 의료 인력, 최초 대응자, 기타 필수 및 최전선 작업자 사이의 SARS-CoV-2 감염 발생: 2021년 1월-9월 미국 8개 지역

Article

Published on 2022-05-012022-09-11
Journal: Influenza and Other Respiratory Viruses [Category] COVID19(2023년), SARS, 변종,