Vaccination against SARS-CoV-2 in Haemodialysis Patients: Spike’s Ab Response and the Influence of BMI and Age혈액 투석 환자의 SARS-CoV-2 예방 접종: Spike의 Ab 반응과 BMI 및 연령의 영향Multicenter Study Published on 2022-08-152022-09-12 Journal: International Journal of Environmental Research an [Category] SARS, 진단, [키워드] age antibody BMI BNT162b2 mRNA body mass index carried Chronic kidney disease Cohort cohort of patient Complete composed control group correlation COVID-19 declined dialysis Elderly patient faster greater groups humoral Humoral response identify IgG IgG antibody immune response immune system Immunity influence median multicenter older patient participant Patient Pfizer-BioNTech Portugal response SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection selected serum significantly spike the median titres vaccination Vaccine younger patient [DOI] 10.3390/ijerph191610091 PMC 바로가기 [Article Type] Multicenter Study
Context-specific emergence and growth of the SARS-CoV-2 Delta variant Research Published on 2022-08-112022-10-05 Journal: Nature [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] Analysis Contact Contact tracing COVID-19 Delta delta variant Delta wave dissemination England faster genomic data global genome growth heterogeneity heterogeneous Immunity Increasing India Intervention introduced Invasion Lineage Local occurred omicron onward transmission quarantine receiving reduce reduced relative growth SARS-CoV-2 Spread the SARS-CoV-2 Transmission Travel variant virus virus genome [DOI] 10.1038/s41586-022-05200-3 [Article Type] Research
Factors Associated with Burnout among Resident Physicians Responding to the COVID-19 Pandemic: A 2-Month Longitudinal Observation StudyObservational Study Published on 2022-08-072022-10-05 Journal: International Journal of Environmental Research an [Category] 임상, [키워드] Burnout COVID-19 COVID-19 pandemic demographic characteristics Effect emotional examined Factor faster graduate medical education hospital implication IMPROVE initial Intervention less longitudinal participant Period physical physician predictor prevalent promote prospective design recruited repeated reported required resident resident burnout resident wellness. Responding Self-efficacy severity Sociodemographic Stage Support variables [DOI] 10.3390/ijerph19159714 PMC 바로가기 [Article Type] Observational Study
Piezoelectric point-of-care biosensor for the detection of SARS-COV-2 (COVID-19) antibodiesResearch article Published on 2022-08-012022-10-05 Journal: Sensing and Bio-Sensing Research [Category] 진단, 치료기술, [키워드] analyzed antibodies antibody Antigen assays caused changes COVID-19 diagnose diagnostic diagnostics different disease disease facilitate faster feature Frequency global pandemic high mortality In-vitro Novel coronavirus Piezoelectric biosensor platform POC biosensor point-of-care resulting SARS SAW selective sensitivity sensor specific disease Surface acoustic waves tested the disease the vaccine Vaccine development [DOI] 10.1016/j.sbsr.2022.100510 [Article Type] Research article
CLEVER assay: A visual and rapid RNA extraction-free detection of SARS-CoV-2 based on CRISPR-Cas integrated RT-LAMP technologyCLEVER 분석: CRISPR-Cas 통합 RT-LAMP 기술을 기반으로 하는 SARS-CoV-2의 시각적이고 신속한 RNA 추출 없는 검출Article Published on 2022-08-012022-09-11 Journal: Journal of Applied Microbiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 clinical sensitivity clustered regularly interspaced short palindromic repeats coronavirus COVID-19 COVID-19 diagnosis COVID-19 outbreak COVID-19 pandemic CRISPR CRISPR-Ca CRISPR-Cas12 develop diagnose Diagnosis epidemiological equipment extraction-free method faster guide RNA hospital human body infected patients integration Internal control involved Isolation isothermal amplification lab LAMP lateral flow lateral flow readout. limit logistics Loop-mediated isothermal amplification major defect management nasopharyngeal offer Oropharyngeal overcome Palindromic point-of-care POP7 Region Repeat reverse transcription RNA RNA extraction RNA isolation RNase P RT-LAMP SARS-CoV-2 SARS-CoV-2 detection severe acute respiratory syndrome Coronavirus Significance specificity stick the patient urgency Visual with COVID-19 [DOI] 10.1111/jam.15571 PMC 바로가기 [Article Type] Article
A novel multi-scale based deep convolutional neural network for detecting COVID-19 from X-raysResearch article Published on 2022-08-012022-10-05 Journal: Applied Soft Computing [Category] 진단, 치료기술, [키워드] Accuracy airway epithelial cell Antibody test Antigen baseline Chest computed tomography chest X-ray conducted COVID-19 COVID-19 diagnosis COVID-19 dissemination COVID-19 pandemic COVIDx CXR deep neural network develop diagnose Efficacy evaluate faster feature FIVE global public health infecting Internet of Things knowledge less limitation lung Lung infection molecular test MONITOR pandemic Patient Radiography researcher respiratory tract severity of COVID-19 Treatment variety X-ray [DOI] 10.1016/j.asoc.2022.109109 [Article Type] Research article
Plant formulation ATRICOV 452 in improving the level of COVID-19 specific inflammatory markers in patientsResearch article Published on 2022-08-012022-10-05 Journal: Contemporary Clinical Trials Communications [Category] 바이오마커, 신약개발, 임상, [키워드] adverse event assigned Care clinical trial conducted COVID-19 COVID-19 patient CTRI determine dose dropped effective Efficacy evaluate faster Frequency healthcare healthy healthy volunteer hospital Human Importance IMPROVE Inflammatory marker inflammatory markers objective organ system oxygen Patient phase Phase 1 Phase 2 phase 2 trial Placebo plant Plant formulation (ATRICOV 452) primary analysis population randomization receive reduce Registration Result Safe setting Standard of care Support therapeutic intervention Tolerability treatment group Trial Volunteer [DOI] 10.1016/j.conctc.2022.100961 [Article Type] Research article
Effect of Molnupiravir on Biomarkers, Respiratory Interventions, and Medical Services in COVID-19 : A Randomized, Placebo-Controlled Trial코로나19의 바이오마커, 호흡기 중재 및 의료 서비스에 대한 몰누피라비르의 효과 : 무작위, 위약 대조 시험Randomized Controlled Trial Published on 2022-08-012022-09-11 Journal: Annals of internal medicine [Category] COVID19(2023년), MERS, SARS, 바이오마커, 임상, [키워드] 95% CI Analysis assigned baseline benefit C-reactive protein C-reactive protein (CRP Care change clinical benefit clinically Concentration COVID-19 CRP death discharge discharged double-blind Effect evaluated faster Hospitalization Hospitalized identify immunized improvement Improvements Inc Invasive mechanical ventilation less LLC median medical service medical services Mild mild to moderate Mild to moderate COVID-19 Moderate COVID-19 molnupiravir Older oxygen oxygen saturation participant performed Phase 3 Placebo placebo-controlled placebo-treated participant placebo-treated participants potential clinical benefit progression randomization Randomized Randomly receiving reduction in Relative risk respiratory respiratory intervention respiratory interventions risk risk factor Risk factors risk reduction SARS-CoV-2 secondary service severe disease Sharp subsidiary therapy Trial [DOI] 10.7326/M22-0729 PMC 바로가기 [Article Type] Randomized Controlled Trial
Molecular mechanism of antibiotic resistance induced by mono- and twin-chained quaternary ammonium compounds단쇄 및 쌍쇄 4차 암모늄 화합물에 의한 항생제 내성의 분자 메커니즘Article Published on 2022-08-012022-09-11 Journal: The Science of the total environment [Category] 유전자 메커니즘, [키워드] accelerated Ammonium Antibiotic resistance Antibiotics BAC benzalkonium Benzalkonium chloride Cell chloride Compound Concentration contributed COVID-19 pandemic DDAC Didecyldimethylammonium Didecyldimethylammonium chloride E. coli Evolution exposure to faster FIVE inhibitory inhibitory concentration K-12 mechanism minimum molecular mechanism Multidrug resistance Mutagenesis Mutation outbreak outer membrane phenotypic Protein rifampicin risk RNA polymerase sensitivity Sequencing significantly Usage whole-genome sequencing [DOI] 10.1016/j.scitotenv.2022.155090 PMC 바로가기 [Article Type] Article
The unmitigated profile of COVID-19 infectiousnessCOVID-19 전염성의 완화되지 않은 프로필Observational Study Published on 2022-08-012022-09-11 Journal: eLife [Category] SARS, 변종, [키워드] Alpha alpha and delta variants Analysis assumed China Computational biology COVID-19 delta variant early stage early stages Effectiveness Epidemics epidemiological Epidemiology estimate faster framework generation interval global health growth growth rate help Human individual infected individual infected individuals infected with SARS-CoV-2 infectiousness initial intervals Isolation Measures Mitigation outbreak pandemic quarantine quarantine measures robust SARS-CoV-2 sensitivity analysis spread of COVID-19 statistical Systems biology temporal dynamics thought Transmission variants variants of concern VOCs [DOI] 10.7554/eLife.79134 PMC 바로가기 [Article Type] Observational Study