Impact of age, sex and medical history on adverse reactions to the first and second dose of BNT162b2 mRNA COVID-19 vaccine in Japan: a cross-sectional studyResearch Published on 2022-02-232022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, COVID19(2023년), Fulltext, MERS, SARS, [키워드] acute respiratory syndrome adverse effect Adverse reaction Adverse reactions age analyzed BNT162b2 caused collected coronavirus coronavirus disease correlation COVID-19 COVID-19 vaccine cross-sectional dental dose fatigue female females first vaccination headache Impact incidence injection Japan Logistic regression analysis male mRNA of BNT162b2 Older profile promoted Questionnaires recipients regression analysis Result SARS-CoV-2 second dose second vaccination severity Sex significant negative correlation significantly higher subject university vaccination younger people [DOI] 10.1186/s12879-022-07175-y PMC 바로가기 [Article Type] Research
Decline in Antibody Concentration 6 Months After Two Doses of SARS-CoV-2 BNT162b2 Vaccine in Solid Organ Transplant Recipients and Healthy ControlsSARS-CoV-2 BNT162b2 백신 2회 접종 후 6개월 동안 고형 장기 이식 환자 및 건강한 대조군에서 항체 농도 감소Immunology Published on 2022-02-232022-09-12 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 95% CI acute respiratory syndrome age Anti-RBD IgG anti-receptor-binding domain antibody BNT162b2 Cancer cellular response clinical impact Comorbidity Concentration Control controls Coronavirus-2 Corticosteroid COVID-19 de novo Decline declined determine dose examined Factor first dose first vaccination geometric mean concentration GMC healthy control healthy controls humoral IgG immunogenicity Immunoglobulin indicated kidney lung Month neutralizing capacity of BNT162b2 previous study RBD recipient recipients response Result risk SARS-CoV-2 SARS-CoV-2 BNT162b2 second dose Solid solid organ transplant solid organ transplant recipient SOT T-cell Response Transplant Treatment vaccination Vaccine vaccine response were measured [DOI] 10.3389/fimmu.2022.832501 PMC 바로가기 [Article Type] Immunology
Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in EnglandResearch Article Published on 2022-02-222022-10-29 Journal: PLoS Medicine [Category] COVID-19, COVID19(2023년), SARS, [키워드] absolute increase Accuracy adjusted Adults age age and sex analysed Analysis anticoagulant medication antiplatelet Asian association black blood pressure BNT162b2 BNT162b2 vaccines case finding ChAdOx1 ChAdOx1-S coded cohort study confidence interval confounding factors Coronavirus infection covariate covariates COVID-19 COVID-19 mortality COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines Deprivation diabetes diagnostic dose DVT Effect effort Electronic health record Electronic health records England estimate estimates event first vaccination Frequency hazard ratio healthcare Hospital admission hospitalisation hospitalised HRs hypertension identify IMPROVE incidence incidence rate increase in increased risk increases in limitation medication morbidity morbidity and mortality Myocardial infarction outcome performed Platelet population level population-based cohort Positive predictive value prevaccination Rate reducing reported researcher residual confounding risk selected Sex smoking stroke therapy threshold thrombosis thrombotic event Thrombotic events vaccination Vaccine Vaccines venous Venous thrombosis white William [DOI] 10.1371/journal.pmed.1003926 PMC 바로가기 [Article Type] Research Article
The Humoral Immune Response of the ChAdOx1 nCoV-19 Vaccine in Maintenance Dialysis Patients without Prior COVID-19 InfectionArticle Published on 2022-02-212022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] age anti-receptor-binding-domain antibody antibody Antibody Response AZ vaccine B cell blood test ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 (Oxford-AstraZeneca, AZ) vaccine chronic Chronic dialysis CKD COVID-19 COVID-19 vaccine cytometry analysis delayed response dialysis dose Efficacy eight evaluated first vaccination Flow immune immune response Infection Kidney disease maintenance Oxford-AstraZeneca participant Patient performed positive positive antibody response proliferative RBD reduced responders response SARS-CoV2 significantly lower Spike protein the receptor-binding domain the S1 subunit the SARS-CoV-2 vaccination Vaccine [DOI] 10.3390/vaccines10020338 PMC 바로가기 [Article Type] Article
Decline of Humoral Responses 6 Months after Vaccination with BNT162b2 (Pfizer–BioNTech) in Patients on HemodialysisArticle Published on 2022-02-182022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] absence analyzed anti-SARS-CoV-2 IgG antibody association binding binding antibody BNT162b2 chemiluminescent immunoassay Chronic kidney disease CLIA COVID-19 Decline declined dose first vaccination Hemodialysis humoral immune response Humoral response identify immune response infected with SARS-CoV-2 median Month mRNA vaccines multivariable naïve Neutralizing activity Neutralizing antibodies Neutralizing antibody titer Patient Pfizer–BioNTech receiving Regression model response risk risk factor SARS-CoV-2 SARS-CoV-2 IgG Seroconversion seroconversion rate serum albumin spike glycoprotein vaccination vaccination schedule vaccine response vanishing was tested was used were measured wild-type virus [DOI] 10.3390/vaccines10020327 PMC 바로가기 [Article Type] Article
Intensity and Dynamics of Anti-SARS-CoV-2 Immune Responses after BNT162b2 mRNA Vaccination: Implications for Public Health Vaccination StrategiesArticle Published on 2022-02-172022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] Affect age Antibody responses Autoimmune disease automated BNT162b2 BNT162b2 mRNA cell-mediated immune response cellular response Cellular responses correlation COVID-19 COVID-19 infection COVID-19 vaccination demonstrated dose Dynamics ELISA assays enrolled evaluated first dose first vaccination humoral Humoral response IgA IgA response IgA titer IgG IgG response IgG responses immunization implication individual information intensity Laboratory majority median Microparticle of BNT162b2 Participants positive antibody response positively correlated Public public health required response second vaccination significantly Strategy systemic adverse reaction T cell responses vaccinated individuals vaccination Vaccination strategies were assessed [DOI] 10.3390/vaccines10020316 PMC 바로가기 [Article Type] Article
COVID-19 Vaccination Coverage in Patients with Rheumatic Diseases in a German Outpatient Clinic: An Observational StudyCommunication Published on 2022-02-072022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] 95% CI 95% confidence interval age asked connective tissue disease Coverage COVID-19 COVID-19 pandemic COVID-19 vaccination effective first vaccination Infection Influenza majority medication Odds ratio Outpatient Patient patients pneumococcus Probability raise reason reported rheumatic disease Rheumatic diseases rheumatoid arthritis risk Safe SARS-CoV-2 SARS-CoV-2 vaccination severe COVID-19 Side effects spondyloarthritis Streptococcus pneumoniae susceptibility tested the vaccine unmet need vaccination vaccination rate vaccination rates Vaccine [DOI] 10.3390/vaccines10020253 PMC 바로가기 [Article Type] Communication
mRNA Covid-19 vaccines in pregnancy: A systematic reviewResearch Article Published on 2022-02-022022-10-28 Journal: PLoS ONE [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] adverse event adverse events Adverse reaction antibody Antibody Response antibody transfer article available data booster clinical Cochrane Library conducted Coronavirus disease 2019 criteria database described develop dose elicit European fatigue fetal first vaccination FIVE headache IgG infection rate injection interval investigated latency Local manual Moderna mRNA mRNA vaccine mRNA vaccines mRNA-based vaccine objective observational study Pain Pfizer–BioNTech Pregnancy pregnant women Prevent registry reported Research responses Result risk factor robust Safe SARS-CoV-2 SARS-COV-2 infection searched Seven suggested systematic review systemic adverse events the WHO union vaccination Vaccine vaccine dose were excluded [DOI] 10.1371/journal.pone.0261350 PMC 바로가기 [Article Type] Research Article
Anti-SARS-CoV-2 mRNA vaccines as inducers of humoral response against apolipoprotein A-1?Apolipoprotein A-1에 대한 체액 반응의 유도제로서의 Anti-SARS-CoV-2 mRNA 백신?Article Published on 2022-02-012022-09-12 Journal: European Journal of Clinical Investigation [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] AAA1 Affect anti-SARS-CoV-2 anti-SARS-CoV-2 mRNA vaccines anti-SARS-CoV-2 vaccine apolipoprotein A-1 association autoantibodies Autoimmune Autoimmune response baseline Biomarker collected components COVID-19 density first vaccination fraction healthy control healthy controls humoral IgG IgG level IgG response immunoassays individual individuals induce inducer injection lipoprotein Local median mRNA vaccine mRNA-based observé outcomes Patient patients Population populations Prognosis Protein protocol raised recipient retrieved rheumatoid arthritis SARS-CoV-2 second vaccination serology shown significant increase Symptom systemic translate vaccination were measured were recorded [DOI] 10.1111/eci.13713 PMC 바로가기 [Article Type] Article
SARS-CoV-2 antibody and T cell responses one year after COVID-19 and the booster effect of vaccination: A prospective cohort study코로나19 1년 후 SARS-CoV-2 항체 및 T 세포 반응과 백신 접종의 부스터 효과: 전향적 코호트 연구Article Published on 2022-02-012022-09-11 Journal: The Journal of Infection [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Ad26 Ad26.COV2-S Anti-RBD IgG antibody Antibody Response Blood BNT162b2 booster ChAdOx1 ChAdOx1-S comparable Concentration COVID-19 COVID-19 vaccination COVID-19 vaccine detectable first vaccination healthcare worker Healthcare workers IgG IgG response IgG responses immune response immune responses Immunity Immunoglobulin Immunoglobulin G individual individuals infected individuals IQR Mild mild to moderate Mild to moderate COVID-19 Moderate COVID-19 mononuclear cell mononuclear cells mRNA mRNA-1273 PBMCs Peripheral blood Peripheral blood mononuclear cells prospective cohort prospective cohort study RBD IgG response retained SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection second second vaccination seroconverted spot-forming cell suffered T cell T cell response T cell responses vaccination vaccine-induced immune response vaccine-induced immune responses [DOI] 10.1016/j.jinf.2021.12.003 PMC 바로가기 [Article Type] Article