Gene ontology – Page 6 – Communicable Diseases Research

The risk of pancreatic adenocarcinoma following SARS-CoV family infection

SARS-CoV 가족 감염 후 췌장 선암의 위험

Article

Published on 2021-06-212022-09-10
Journal: Scientific Reports [Category] MERS, SARS, 신종인플루엔자, 유전자 메커니즘, 치료법,

Genome‐wide screening of SARS‐CoV‐2 infection‐related genes based on the blood leukocytes sequencing data set of patients with COVID‐19

Research Article

Published on 2021-05-282022-11-01
Journal: Journal of medical virology [Category] COVID-19, SARS,

[키워드] ACE2 acute respiratory syndrome adverse effect Analysis analyzed AUC AUC value bioinformatics blood leukocyte calculated caused contribute coronavirus Coronavirus disease 2019 COVID‐19 COVID‐19 patient COVID‐19 CTSB CTSL DEGs Diagnosis diagnostic differentially expressed gene disease enrichment analysis Epidemic EPSTI1 expressed expression function Gene ontology GEO database Health IFI27 IFIT3 leukocyte Logistic regression analysis mechanism OASL Patient positively correlated Protein–protein interaction risk ROC Curve SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 screened sequencing data therapeutic therapeutic target TMPRSS2 Treatment USP18 virus XAF1
[DOI] 10.1002/jmv.27093 PMC 바로가기 [Article Type] Research Article

Health monitoring in birds using bio-loggers and whole blood transcriptomics

Article

Published on 2021-05-242023-05-31
Journal: Scientific Reports [Category] Fulltext, 조류인플루엔자,

[키워드] Gene Expression Gene ontology Gene regulatory networks High-throughput screening immunology Infectious diseases Innate immune cells Non-model organisms RNA sequencing
[DOI] 10.1038/s41598-021-90212-8 PMC 바로가기 [Article Type] Article

In silico analysis suggests the RNAi-enhancing antibiotic enoxacin as a potential inhibitor of SARS-CoV-2 infection

In silico 분석은 RNAi 강화 항생제 enoxacin이 SARS-CoV-2 감염의 잠재적 억제제임을 시사합니다.

Article

Published on 2021-05-132022-09-10
Journal: Scientific Reports [Category] SARS, 유전자 메커니즘, 치료제,

[키워드] Analysis anti-SARS-CoV-2 antibiotic antiviral activity component components computational tool COVID-19 COVID-19 treatment Critical Cytokines Data integration Data processing database databases Dicer drug candidate Effects enoxacin Exacerbation Gene ontology Gene regulatory networks highlight host cell identify Infection inhibitor lung mechanism microRNA Molecular biology pathway pro-inflammatory cytokines Protein recent Regulatory Replication reported RNA genome RNAi pathway SARS-CoV-2 SARS-CoV-2 genome SARS-COV-2 infection stem cells the disease the SARS-CoV-2 the SARS-CoV-2 genome transcription factor transcription factors Treatment Viral viral entry viral infection viral replication
[DOI] 10.1038/s41598-021-89605-6 PMC 바로가기 [Article Type] Article

Potential Mechanism Prediction of Herbal Medicine for Pulmonary Fibrosis Associated with SARS-CoV-2 Infection Based on Network Analysis and Molecular Docking

Pharmacology

Published on 2021-04-122022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

[키워드] analyses Analysis approach binding activity CCP Chinese Chinese herbal medicine component components contribute COVID-19 database distribution enrichment analysis exhibited expression finding Gene ontology health-care Herbal high risk IL-6 include indicated Infection inhibit involved KEGG Kyoto MAPK MAPK signaling mechanism Medicine metabolism MMP9 molecular docking molecular mechanism molecular mechanisms multiple pathways network network pharmacology offer pathway Patient Potential PPI predict prediction prescription protein-protein interaction pulmonary pulmonary fibrosis receptor SARS-CoV-2 SARS-COV-2 infection signaling pathway signaling pathways suggested target targets TGF-β1 the disease the SARS-CoV-2 TNF-α treatment for COVID-19 VEGF Version
[DOI] 10.3389/fphar.2021.602218 PMC 바로가기 [Article Type] Pharmacology

Whole-Transcriptome RNA Sequencing Reveals Significant Differentially Expressed mRNAs, miRNAs, and lncRNAs and Related Regulating Biological Pathways in the Peripheral Blood of COVID-19 Patients

전체 전사체 RNA 시퀀싱은 COVID-19 환자의 말초 혈액에서 유의미하게 차별적으로 발현된 mRNA, miRNA, lncRNA 및 관련 조절 생물학적 경로를 나타냅니다

Research Article

Published on 2021-04-012022-09-10
Journal: Mediators of Inflammation [Category] MERS, SARS, 유전자 메커니즘,

[키워드] “cytokine storm” acute respiratory syndrome acute respiratory syndrome coronavirus AKT1 Analysis Antigen antigen processing Biological biosynthetic characterized China coding collected competing control group controls coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients COVID-19 sample COVID-19 samples CXCL8 cytokine cytokine production Cytokine storm cytotoxicity diagnostic biomarker Diagnostic biomarkers differentially expressed downregulated enrichment analysis excessive cytokine production FCGR2A Functional enrichment analyses Gene ontology glycogen ground-glass opacity healthy controls healthy donor healthy donors highlight hub genes indicated Inflammation Interaction involved leukocyte leukocytes lncRNA long noncoding RNA lung tissues lymphocyte Lymphocytes mechanism Messenger RNA messenger RNAs microRNA MicroRNAs Migration miRNA miRNAs mRNA mRNAs noncoding RNA Noncoding RNAs pandemic Pathogenesis peripheral Peripheral blood positive potential mechanism potential mechanisms PPI presenting protein-protein interaction Regulating Regulation Regulatory respiratory resulting RNA SARS-CoV-2 selected Sequencing severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 signaling pathway Significant significantly STAT3 systemic inflammation T cell T cell activation target the healthy therapeutic tissue TLR2 TNFRSF1B upregulated
[DOI] 10.1155/2021/6635925 PMC 바로가기 [Article Type] Research Article

Human coronaviruses in idiopathic Parkinson’s disease: Implications of SARS-CoV-2’s modulation of the host’s transcriptome

특발성 파킨슨병의 인간 코로나바이러스: SARS-CoV-2의 숙주 전사체 조절의 의미

Article

Published on 2021-04-012022-09-11
Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 유전자 메커니즘, 치료기술,

[키워드] among others analyses Analysis comparison Control coronavirus determine disease Diseases Effect enriched pathways enrichment analyses enrichment analysis false discovery rate FDR Gene Expression Gene ontology Gene Set Enrichment Analyses GSEA head Head-to-head comparisons Host Human human coronavirus human coronaviruses Huntington's disease immune response indicated modulation mononuclear cell motor nucleus mRNA NAFLD neurodegeneration neurodegenerative Neuroinvasive nigra not limited Ontology overlap overlapping parasitism parkinson s disease Parkinson's Disease Pathogenesis pathway Patient PBMC performed Peripheral blood Perturbation retrieved SARS-CoV-2 SARS-COV-2 infection scrutiny statistically significant substantia substantia nigra Surveillance tissue tissues Transcriptome transcriptomic Whole blood
[DOI] 10.1016/j.meegid.2021.104733 PMC 바로가기 [Article Type] Article

Quantitative proteomics reveals a broad-spectrum antiviral property of ivermectin, benefiting for COVID-19 treatment

정량적 단백질체학은 COVID-19 치료에 도움이 되는 이버멕틴의 광범위한 항바이러스 특성을 나타냅니다

Article

Published on 2021-04-012022-09-11
Journal: Journal of cellular physiology [Category] SARS, 유전자 메커니즘, 치료기술, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alteration Amino acid amino acids Analysis Antibacterial anticancer Antiviral biological processes Cancer cells Cell Cell culture cells cellular components complex coronavirus COVID-19 COVID-19 treatment cytokine Cytokines cytomegalovirus Diseases EBV Epstein-Barr virus G-protein Gene ontology Gene ontology analysis global public health growth factor HCMV Health HIV HIV1 HLA HPV Human Cytomegalovirus Human immunodeficiency virus human papillomavirus identify immunodeficiency virus IMPROVE in vitro Infection inhibit Interaction Ivermectin labeling molecular functions network analysis offer ovarian cancer papillomavirus pathway Pathways Personalized medicine PPI PPI network Predictive Protein Proteins proteomics Quantitative quantitative proteomics regulated Replication replication of SARS-CoV-2 reported reveal SARS-CoV-2/COVID-19 STABLE stable isotope labeling by amino acids in cell culture statistically significant treated Treatment virus virus infection virus-related pathways. was used
[DOI] 10.1002/jcp.30055 PMC 바로가기 [Article Type] Article

Network-based identification genetic effect of SARS-CoV-2 infections to Idiopathic pulmonary fibrosis (IPF) patients

특발성 폐섬유증(IPF) 환자에 대한 SARS-CoV-2 감염의 네트워크 기반 식별 유전 효과

Article

Published on 2021-03-222022-09-11
Journal: Briefings in Bioinformatics [Category] SARS, 유전자 메커니즘, 치료기술, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Analysis association cause common coronavirus coronavirus disease COVID-19 COVID-19 infections dataset differentially expressed differentially expressed gene Differentially expressed genes drug drug molecule drug target fibrosis Gene ontology Genetic genomes hub gene hub genes identify Idiopathic pulmonary fibrosis increased mortality Infection infections Interaction IPF Kyoto lung epithelium cell lung injuries Lung injury miRNA ontology term pathway Patient patients patients with COVID-19 PPI protein-protein interaction protein–protein interactions risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections selected severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity shared pathway shared pathways Spread suggested synergistic synergistic effect the epidemic the SARS-CoV-2 Transcriptomic analyses transcriptomic analysis virus was performed
[DOI] 10.1093/bib/bbaa235 PMC 바로가기 [Article Type] Article

Identification of biomarkers and pathways for the SARS-CoV-2 infections that make complexities in pulmonary arterial hypertension patients

폐동맥 고혈압 환자에서 복잡성을 만드는 SARS-CoV-2 감염에 대한 바이오마커 및 경로 식별

Article

Published on 2021-03-222022-09-11
Journal: Briefings in Bioinformatics [Category] SARS, 바이오마커, 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis Arterial hypertension Biomarker carried caused Compound conditions coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic diagnosed differentially expressed gene EDN1 effective drugs epithelial cell epithelial cells Evidence evidence of expression level expression profiling Extensive gene expression profile Gene expression profiling Gene ontology genomic Genomic analysis human lung human lung epithelial cells hypertension identification identify immune response Infection infections Inflammatory response Inflammatory responses integration lung observation Ontology PAH pathway Patient performed Phylogenetic tree promoter protein-protein interaction provided pulmonary arterial hypertension Regulatory Research respiratory response Ribonucleic acid RNA virus RNA viruses S100A12 S100A8 S100A9 Saa1 SAA2 SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections severe acute respiratory syndrome Coronavirus Signaling signaling pathway signaling pathways significant interaction the SARS-CoV-2 therapeutic these compound these compounds transcriptomic Transcriptomic analyses transcriptomic analysis Transcriptomic profiling Transferrin viruses
[DOI] 10.1093/bib/bbab026 PMC 바로가기 [Article Type] Article