Clinical manifestations of COVID-19 breakthrough infections: A systematic review and meta-analysisCOVID-19 돌발 감염의 임상 양상: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-09-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval Analysis asymptomatic infection Breakthrough infection breakthrough infections clinical manifestation clinical manifestations Clinical outcome Coronavirus 2019 COVID-19 COVID-19 infection COVID-19 infections Delta delta variant Effect Effectiveness examined groups heterogeneity Hospitalization individual individuals Infection Invasive mechanical ventilation Meta-analysis Mortality need for oxygen other variants oxygen oxygen supplementation Patient Relative risk risk Risk factors risk of infection significantly significantly higher statistically statistically significant difference Still study heterogeneity supplemental oxygen systematic review Treatment strategies Vaccine vaccine effectiveness variant variants Web of Science [DOI] 10.1002/jmv.27871 PMC 바로가기 [Article Type] Meta-Analysis
COVID-19 vaccination, incidence, and mortality rates among indigenous populations compared to the general population in Brazil: Describing trends over timeResearch article Published on 2022-09-012022-10-05 Journal: The Lancet Regional Health - Americas [Category] 진단, [키워드] absence Adults age available data Brazil chronic Coverage COVID-19 COVID-19 incidence COVID-19 pandemic COVID-19 vaccination cumulative cumulative mortality death decrease Describing detrimental Effectiveness extreme finding funding General population health inequities Health inequity heterogeneity implementation incidence incidence rate incidence rates Indigenous populations information Isolation Ministry of Health Mortality mortality rate Older Population populations regions reported resource respond supported the vaccine Trends over time vaccination Vaccination strategy Vaccine [DOI] 10.1016/j.lana.2022.100319 [Article Type] Research article
Exploring the risk factors of COVID-19 Delta variant in the United States based on Bayesian spatio-temporal analysisArticle Published on 2022-09-012022-11-16 Journal: Transboundary and emerging diseases [Category] COVID19(2023년), SARS, 변종, [키워드] Analysis Bayesian Bayesian analysis Cluster coefficient collected contagious contribute coronavirus covariate COVID-19 COVID-19 variant cases delta variant develop Effect Epidemic Factor flexible genetic mutation Government group help heterogeneity Hierarchical identify independent variables measure Region risk factor Risk factors SARS-CoV-2 selected space-time model spatial clusters Spread statistical the United State Transmission variable selection variant worsened [DOI] 10.1111/tbed.14623 PMC 바로가기
Delineating COVID-19 immunological features using single-cell RNA sequencingReview article Published on 2022-09-012022-10-05 Journal: The Innovation [Category] 변종, 유전자 메커니즘, 치료기술, 치료제, [키워드] acute respiratory syndrome Analysis applied cell population cellular coronavirus disease Coronavirus-2 COVID-19 COVID-19 patient dataset feature heterogeneity host response immune immune response immunological Infection limitation molecular mechanism multiple tissue organs Pathogenesis Pathways Perspective reveal RNA sequencing SARS-CoV-2 severity single cells Single-cell RNA sequencing Therapies understanding [DOI] 10.1016/j.xinn.2022.100289 [Article Type] Review article
High-Dose versus Low-Dose Corticosteroids in COVID-19 Patients: a Systematic Review and Meta-analysisResearch article Published on 2022-09-012022-10-05 Journal: Journal of cardiothoracic and vascular anesthesia [Category] COVID19(2023년), SARS, 비임상, 임상, [키워드] Admission Analysis certainty of evidence Clinical efficacy coronavirus Corticosteroid Corticosteroids COVID-19 COVID-19 patients demonstrated Dexamethasone did not reduce dose evaluate Evidence group heterogeneity High-dose higher risk Hospital stay hyperglycemia ICU IMPROVE incidence Inconclusive infection rate intensive care low-dose corticosteroid low-dose corticosteroids measurement mechanical ventilation Meta-analysis Methylprednisolone mortality rate no significant difference objective observational study participant patients positive randomized clinical trial Randomized controlled trial Respiratory Support Result review SARS-CoV-2 SARS-CoV-2 PCR setting significant difference systematic review Trial trial sequential analysis [DOI] 10.1053/j.jvca.2022.05.011 [Article Type] Research article
Immediate reinfection with Omicron variant after clearance of a previous SARS-CoV-2 infectionArticle Published on 2022-09-012022-11-16 Journal: Journal of infection and public health [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha variant clearance Combination COVID-19 Delta epidemic peak heterogeneity Immediate immune evasion individuals Infection Italy Lineage Microbiology omicron Patient Primary infection Regional Reinfection RT-PCR test S gene SARS-CoV-2 SARS-COV-2 infection searched Sequencing Transmissibility variant variants whole genome [DOI] 10.1016/j.jiph.2022.07.013 PMC 바로가기
Bimodal distribution pattern associated with the PCR cycle threshold (Ct) and implications in COVID-19 infectionsPCR 주기 역치(Ct)와 관련된 바이모달 분포 패턴 및 COVID-19 감염에 미치는 영향Article Published on 2022-08-252022-09-11 Journal: Scientific Reports [Category] SARS, 변종, 진단, 치료기술, [키워드] 2019-nCoV age bimodal bimodal distribution cell types Chain Reaction Characteristics clinical sample clinical samples Combination Control COVID-19 COVID-19 infection COVID-19 pandemic Ct values cycle threshold disease control Disease progression dissemination distribution DNA epithelial cells examined explain Gender Genome heterogeneity host response implication Infection infection control Integrated DNA Technologies mucosal notable PCR PCR cycle platform polymerase chain reaction positive prevention ranged real-time RT-PCR respiratory respiratory epithelial cells RT-PCR sample collection SARS-CoV-2 stratified TaqPath ThermoFisher Scientific threshold Transmissibility Transmission Viral Viral load viral replication viral variant Viral variants [DOI] 10.1038/s41598-022-18735-2 PMC 바로가기 [Article Type] Article
Heterogeneous responses in Google Trends measures of well-being to the COVID-19 dynamic quarantines in Chile Research Published on 2022-08-252022-10-05 Journal: Scientific Reports [Category] 치료법, [키워드] changes in Chilean coronavirus COVID-19 dynamic Effect Evidence facilitate Google health authorities heterogeneity induce lockdowns measure Psychological quarantine response Spread trend unique [DOI] 10.1038/s41598-022-18514-z [Article Type] Research
Diffuse alveolar damage patterns reflect the immunological and molecular heterogeneity in fatal COVID-19Research article Published on 2022-08-242022-10-05 Journal: EBioMedicine [Category] SARS, 진단, 치료기술, [키워드] alveolar damage Analysis Autopsy Bacteria Candida parapsilosis CD8+ T cells CD8+T cells Cell changes in complex correlated COVID-19 COVID-19 case COVID-19 patients DAD diffuse Diffuse alveolar damage disease eight elevated enriched pathway exhibit Extracellular matrix Factor fatal COVID-19 feature fibroblasts finding foundation funding fungi heart heterogeneity histological humoral immune immune cells immunohistochemistry immunological immunopathology implication innate immune response Lung disease lung tissue Lungs Macrophage macrophages management Melinda Gate modulate molecular multiplex occur Patient performed progression quantified Regeneron Pharmaceuticals response SARS-CoV-2 Secondary infection subsequent Support Swedish the disease Transcriptome Treatment strategies [DOI] 10.1016/j.ebiom.2022.104229 [Article Type] Research article
Poor Antibody Response to BioNTech/Pfizer Coronavirus Disease 2019 Vaccination in Severe Acute Respiratory Syndrome Coronavirus 2-Naive Residents of Nursing HomesBioNTech/Pfizer 코로나바이러스 질병 2019 중증 급성 호흡기 증후군 코로나바이러스 백신 접종에 대한 항체 반응 불량Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus administration age antibody Antibody Response B.1.351 B.1.351 variant Belgium binding antibodies binding antibody BNT162b2 BNT162b2 mRNA BNT162b2 mRNA vaccination Breakthrough infection cluster analysis comorbid conditions comparable coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 death detectable disease domain domains dose General population heterogeneity high risk home immunization Immunoglobulin immunosenescence IMPROVE in some Infection involved Messenger RNA mRNA mRNA vaccination mRNA vaccine Neutralizing Nursing nursing homes old age Poor RBD RBD IgG recruited related disease resident respiratory respond poorly Responder response S1 and S2 SARS-CoV-2 severe acute respiratory syndrome Coronavirus Support the vaccine These data vaccination Vaccine vaccine strain variants variants of concern were assessed wild type [DOI] 10.1093/cid/ciab998 PMC 바로가기 [Article Type] Article