Willingness to participate in COVID-19 vaccine trials; a survey among a population of healthcare workers in UgandaCOVID-19 백신 시험에 참여할 의향, 우간다의 의료 종사자 인구를 대상으로 한 설문 조사Research Article Published on 2021-05-272022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 임상, [키워드] Adverse reaction Adverse reactions affected age altruism analysed aRR attribute binomial Blood candidate vaccine Care chance collected conditions conducted COVID-19 COVID-19 vaccine COVID-19 vaccine trial COVID-19 vaccine trials demographics enrolled evaluate Factor female HCW HCWs Health Health care healthcare worker high risk Hope hospital hypothetical individual information Linear model Local log male Participation Placebo Pregnancy questionnaire receiving reduced Research Result risk SARS-CoV-2 Standard Standard deviation study visit Trial Uganda Vaccine vaccine trial Vaccines [DOI] 10.1371/journal.pone.0251992 PMC 바로가기 [Article Type] Research Article
Mental Health of Young Australians during the COVID-19 Pandemic: Exploring the Roles of Employment Precarity, Screen Time, and Contact with NatureArticle Published on 2021-05-252022-10-30 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] absence affected age assessment association associations Australian confounders Contact contact with contributed core beliefs coronavirus disease COVID-19 COVID-19 pandemic Emerging adulthood employment ENhance Factor Factors flourishing highlight Hope lack less lockdowns Logistic regression Mental mental health mental health problems mental health service mental illness Model Nature pandemic participant potential risk precarity Protective protective factor reported reported symptom Research Risk factors role Screen screen time secure socio-demographic state Stress supported Symptom Symptoms time walking distance were used young people [DOI] 10.3390/ijerph18115630 PMC 바로가기 [Article Type] Article
Investigating the utility of COVID-19 antibody testing in end-stage renal disease patients receiving haemodialysis: a cohort study in the United Kingdom혈액투석을 받는 말기 신질환 환자에서 COVID-19 항체 검사의 유용성 조사: 영국의 코호트 연구Research Published on 2021-04-272022-09-10 Journal: BMC Nephrology [Category] MERS, SARS, 치료기술, [키워드] addition aims Analysis anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG anti-SARS-CoV-2 IgG antibodies anti-SARS-CoV-2 IgG antibody antibodies Antibody Response Antibody testing approved asymptomatic patient asymptomatic patients baseline characteristics Chain Reaction Characteristics Chi-squared test Chi-squared tests cohort study COVID-19 COVID-19 antibody COVID-19 infection death detectable detectable anti-SARS-CoV-2 antibodies determine diagnosis of COVID-19 disease End-stage renal disease epidemiological ESRD groups Haemodialysis help Hope hospital host immunity humoral Humoral response IgG antibodies improvement increased mortality Infection prevention local outbreaks Mann-Whitney U measure median MONITOR number of deaths Other over Patient patients PCR-positive polymerase chain polymerase chain reaction positive Prevent Prevention and control previous diagnosis proportion provide Real-Time Reverse Transcription Polymerase Chain Reaction receiving recruited renal renal disease Result reverse transcription reverse transcription polymerase chain reaction routine clinical practice rRT-PCR SARS-CoV-2 Serological testing Seroprevalence SKS SPSS statistical analysis supplementary material symptomatic Symptoms tested the antibody response the patient the vaccine the vaccines United Kingdom utility was performed were recorded were used with COVID-19 [DOI] 10.1186/s12882-021-02366-2 PMC 바로가기 [Article Type] Research
Editorial: SARS-CoV-2 mRNA Vaccines and the Possible Mechanism of Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT)사설: SARS-CoV-2 mRNA 백신과 백신 유발 면역 혈전성 혈소판 감소증(VITT)의 가능한 메커니즘Editorial Published on 2021-04-262022-09-11 Journal: Medical science monitor : international medical jo [Category] SARS, 유전자 메커니즘, 임상, [키워드] antibody AstraZeneca Autoimmune cavernous sinus cavernous sinus thrombosis ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine clinical trials collaboration coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cross-react death rate editorial Efficacy global pandemic heparin heparin-induced thrombocytopenia Hope morbidity mRNA mRNA vaccine Oxford Platelet platelet factor 4 Prevent safety profile SARS-CoV-2 SARS-CoV-2 spike Science Sinus thrombosis Spread syndrome the SARS-CoV-2 thrombocytopenia thrombosis thrombotic thrombotic event Thrombotic events University of Oxford vaccination virus women [DOI] 10.12659/MSM.932899 PMC 바로가기 [Article Type] Editorial
A human coronavirus evolves antigenically to escape antibody immunity인간 코로나 바이러스는 항체 면역을 피하기 위해 항원 적으로 진화합니다.Research Article Published on 2021-04-082022-08-13 Journal: PLoS Pathogens [Category] Biology and Life Sciences, COVID-19, SARS, [키워드] 229E 229E strain 229E strains 229E viral strain 229E viruses accumulate anti-SARS-CoV-2 titer anti-SARS-CoV-2 titers antibody antibody immunity antigenic evolution common-cold comparable coronavirus coronavirus 229E coronavirus vaccine Coronavirus vaccines Coronaviruses degrade elicited Evolution Hope human coronavirus human coronavirus 229E human sera Hypothesis identify Immunity in some individuals Infection less Mutation neutralization neutralize Neutralizing titer neutralizing titers NTD occur Older other coronaviruses pace PROTECT question re-infect Re-infection Re-infections Receptor-binding domain Region SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccines seasonal coronavirus sera Spike protein strain Strains subsequent the RBD the receptor-binding domain titers vaccination variants of SARS-CoV-2 Viral viral evolution viral mutation Viral mutations viral spike viral strains virus viruses was collected [DOI] 10.1371/journal.ppat.1009453 PMC 바로가기 [Article Type] Research Article
International policies and challenges on the legalization of traditional medicine/herbal medicines in the fight against COVID-19COVID-19와의 싸움에서 전통 의학/한약의 합법화에 대한 국제 정책 및 과제Review Published on 2021-04-012022-08-31 Journal: Pharmacological research [Category] MERS, 신약개발, 치료제, [키워드] analyzed Care China coronavirus disease Coronavirus disease 2019 country COVID-19 Culture develop discrepancy effective Epidemics European example global public health Government Health Health care Herbal herbal medicines Hope in some India knowledge Legalization medication medication history Medicine North outbreak Pneumonia Policy Regulation resource response Safe selected Seven silent South Korea Spread Support theory therapy Traditional Traditional medicine treat Treatment treatment of COVID-19 [DOI] 10.1016/j.phrs.2021.105472 PMC 바로가기 [Article Type] Review
mRNA Vaccines to Prevent COVID-19 Disease and Reported Allergic Reactions: Current Evidence and Suggested ApproachCOVID-19 질병 및 보고된 알레르기 반응을 예방하기 위한 mRNA 백신: 현재 증거 및 제안된 접근 방식Review Published on 2021-04-012022-09-11 Journal: The journal of allergy and clinical immunology. In [Category] 임상, [키워드] administer allergic allergic reaction Allergic reactions allergy American Americans anaphylaxis authorization Care CDC center clinics conjunction Control coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccination COVID-19 vaccine current develop disease control drug effective Emergency Emergency use authorization Epidemiology EUA FDA first dose food global pandemic glycol Guidance guidelines Hope identify individual information Moderna mRNA offer Pfizer-BioNTech Phase 3 trials polyethylene Polyethylene glycol Polysorbate prevention public health raised reaction reassurance receive recommendation regulatory agencies Regulatory Authorities risk stratification staff Support the vaccine U.S. Food and Drug Administration vaccination Vaccine widespread [DOI] 10.1016/j.jaip.2020.12.047 PMC 바로가기 [Article Type] Review
Old drug, new Trick? The rationale for the treatment of COVID-19 with activated protein C오래된 약, 새로운 트릭? 활성화된 단백질 C로 코로나19를 치료하는 근거Article Published on 2021-04-012022-09-11 Journal: Medical Hypotheses [Category] 치료법, 치료제, [키워드] activated activated protein C adaptive Antiviral agents antiviral treatments apixaban approach Aspirin clinical trial Coagulation consequence convalescent plasma COVID-19 COVID-19 pandemic COVID-19 patients COVID-19 therapeutics COVID-19 therapeutics. current described dysregulated immune response evaluated followed by heparin heparins Hope Hypothesis identify immune immune response immunomodulator immunomodulators Infection Inflammatory mechanism monoclonal antibodies Protein protein C researcher steroid Steroids therapeutic interventions therapeutic target Therapies therapy treating COVID-19 patient Treatment [DOI] 10.1016/j.mehy.2021.110537 PMC 바로가기 [Article Type] Article
Temperature dependence of COVID-19 transmissionCOVID-19 전염의 온도 의존성Article Published on 2021-04-012022-09-11 Journal: The Science of the total environment [Category] SARS, 치료기술, [키워드] Affect analyzed average base capita country COVID-19 COVID-19 pandemic COVID-19 transmission dataset decrease doubling early stage Environmental risk factors Epidemic Epidemiology Evidence exponential growth fitting GDP growth growth rate homogeneous Hope initial less linear lockdown policies Masks measure P-value Prevent regions risk Safe second wave significantly social distancing Spread temperature the epidemic threshold Ventilation warm [DOI] 10.1016/j.scitotenv.2020.144390 PMC 바로가기 [Article Type] Article
Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics고 처리량 스크리닝 데이터베이스의 마이닝은 COVID-19 치료제의 잠재적 표적으로서 AP-1 및 자가포식 경로를 나타냅니다Article Published on 2021-03-242022-09-10 Journal: Scientific Reports [Category] SARS, 신약개발, 유전자 메커니즘, 임상, 치료제, [키워드] addition Anti-SARS-CoV-2 Activity Antiviral AP-1 approved approved drug approved drugs autophagy autophagy pathway Candidates caused class coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 therapeutics CPE Cytopathic effect Data mining database drug drug activity drug library effective effort global pandemic High-throughput screening Hope house human clinical trials in vivo mechanism New coronavirus new coronavirus SARS-CoV-2 phenotypic Potential treatment potential treatments profile pursuit reveal SARS-CoV-2 SARS-COV-2 infection signaling pathway significantly target Target identification therapeutic Viral [DOI] 10.1038/s41598-021-86110-8 PMC 바로가기 [Article Type] Article